AutismKB 2.0

Annotation Detail for COMP


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Basic Information Top
Gene Symbol:COMP ( EDM1,EPD1,MED,MGC131819,MGC149768,PSACH,THBS5 )
Gene Full Name: cartilage oligomeric matrix protein
Band: 19p13.11
Quick LinksEntrez ID:1311; OMIM: 600310; Uniprot ID:COMP_HUMAN; ENSEMBL ID: ENSG00000105664; HGNC ID: 2227
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
121N-linked (GlcNAc...) (Potential).
369Cell attachment site (Potential).
742N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
121N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
742N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
24Phosphoserine(CDC2)HMM predict
24Phosphoserine(IKK)HMM predict
114S-palmitoylHMM predict
121N-linkedHMM predict
158Phosphotyrosine(Abl)HMM predict
159O-linkedHMM predict
209S-palmitoylHMM predict
339Phosphothreonine(CK2)HMM predict
596SulfotyrosineHMM predict
741CysteineHMM predict
742N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000095
  • Location:chr19 18754582-18763113
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 18763071 18763331 260 88
H3K27me3 colorectalcancer 18768054 18768443 389 5135
P300 T30-glioblastomaGSE21026 18781107 18781765 658 18323
RARA MCF7GSE15244 18770296 18770938 642 7504
hScc1 BcellGSE12603 18772207 18772938 731 9459
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 18752299 18752901 602 1983
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 18757382 18757977 595 0
CTCF G2GSE9613 18760313 18760547 234 0
H3K27me3 colorectalcancer 18762085 18762651 566 0
SRF GMOGSE8489 18761906 18762686 780 0
hScc1 BcellGSE12603 18756687 18757298 611 0
hScc1 BcellGSE12603 18757837 18758196 359 0
hScc1 BcellGSE12603 18760011 18760764 753 0
hScc1 BcellGSE12603 18762051 18763298 1247 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-199a-3p hsa-mir-199a-1 19 19251704
hsa-miR-199a-3p hsa-mir-199a-2 1 19251704
hsa-miR-200b hsa-mir-200b 1 18573151
hsa-miR-200b* hsa-mir-200b 1 18573151
hsa-miR-25 hsa-mir-25 7 18573151
hsa-miR-25* hsa-mir-25 7 18573151
hsa-miR-26a hsa-mir-26a-1 3 18573151
hsa-miR-26a hsa-mir-26a-2 12 18573151
hsa-miR-30d hsa-mir-30d 8 18573151
hsa-miR-30d* hsa-mir-30d 8 18573151
hsa-miR-337-3p hsa-mir-337 14 18573151
hsa-miR-337-5p hsa-mir-337 14 18573151
hsa-miR-377 hsa-mir-377 14 18573151
hsa-miR-377* hsa-mir-377 14 18573151
hsa-miR-423-3p hsa-mir-423 17 18573151
hsa-miR-423-5p hsa-mir-423 17 18573151
hsa-miR-489 hsa-mir-489 7 18573151
hsa-miR-496 hsa-mir-496 14 18573151
hsa-miR-515-3p hsa-mir-515-1 19 18573151
hsa-miR-515-3p hsa-mir-515-2 19 18573151
hsa-miR-9 hsa-mir-9-1 1 18573151
hsa-miR-9 hsa-mir-9-2 5 18573151
hsa-miR-9 hsa-mir-9-3 15 18573151
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018