AutismKB 2.0

Annotation Detail for IRAK1BP1


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Basic Information Top
Gene Symbol:IRAK1BP1 ( AIP70,MGC138458,MGC138460,SIMPL )
Gene Full Name: interleukin-1 receptor-associated kinase 1 binding protein 1
Band: 6q14.1
Quick LinksEntrez ID:134728; OMIM: NA; Uniprot ID:IKBP1_HUMAN; ENSEMBL ID: ENSG00000146243; HGNC ID: 17368
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
56Phosphoserine (By similarity).
62Phosphoserine (By similarity).
235Phosphoserine (By similarity).
237Phosphothreonine (By similarity).
242Phosphoserine (By similarity).
247Phosphothreonine (By similarity).
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001010844
  • Location:chr6 79633907-79665037
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 79633576 79633936 360 152
TAF k562GSE8489 79633305 79633969 664 271
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 79677158 79677371 213 12227
Oct1 H2O2-HelaGSE14283 79678492 79678529 37 13473
Oct1 HelaGSE14283 79678491 79678529 38 13473
TAF HelaGSE8489 79673814 79674119 305 8929
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 79634146 79634356 210 0
ETS1 JurkatGSE17954 79633504 79634788 1284 0
H3ac HepG2E 79634255 79634661 406 0
Nanog ESGSE20650 79633911 79634606 695 0
PHF8 Hs68plusFBSGSE20725 79633472 79634500 1028 0
hScc1 BcellGSE12603 79633720 79634319 599 0
hScc1 CdLSGSE12603 79633675 79634511 836 0
p130 shRbQuiescentGSE19898 79633884 79634598 714 0
p130 shRbSenescentGSE19898 79634054 79634406 352 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018