AutismKB 2.0

Annotation Detail for STXBP5


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Basic Information Top
Gene Symbol:STXBP5 ( FLJ30922,LGL3,LLGL3,MGC141942,MGC141968,Nbla04300 )
Gene Full Name: syntaxin binding protein 5 (tomosyn)
Band: 6q24.3
Quick LinksEntrez ID:134957; OMIM: 604586; Uniprot ID:STXB5_HUMAN; ENSEMBL ID: ENSG00000164506; HGNC ID: 19665
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
723Phosphoserine; by PKA (By similarity).
759Phosphoserine.
762Phosphothreonine.
782Phosphoserine.
784Phosphothreonine.
785Phosphoserine.
1058Phosphoserine (By similarity).
Location(AA) Modifications Resource
723Phosphoserine (by PKA) (By similarity).Swiss-Prot 53.0
762Phosphothreonine.Swiss-Prot 53.0
782Phosphoserine (By similarity).Swiss-Prot 53.0
785Phosphoserine (By similarity).Swiss-Prot 53.0
1058Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
17Phosphoserine(CK2)HMM predict
21Phosphoserine(IKK)HMM predict
146PhosphothreonineHMM predict
234SulfotyrosineHMM predict
268Phosphoserine(CDC2)HMM predict
363Phosphotyrosine(Abl)HMM predict
447Phosphotyrosine(EGFR)HMM predict
556Phosphothreonine(CDC2)HMM predict
572Phosphoserine(IKK)HMM predict
586O-linkedHMM predict
586Phosphoserine(CK1)HMM predict
605Phosphoserine(CDC2)HMM predict
605Phosphoserine(PKG)HMM predict
684Phosphoserine(CDK)HMM predict
684Phosphoserine(CDC2)HMM predict
684PhosphoserineHMM predict
692Phosphoserine(IKK)HMM predict
712Phosphoserine(IKK)HMM predict
712Phosphoserine(CDC2)HMM predict
715Phosphoserine(IKK)HMM predict
715Phosphoserine(CK2)HMM predict
715O-linkedHMM predict
719Phosphoserine(CDC2)HMM predict
723Phosphoserine(CK2)HMM predict
723PhosphoserineHMM predict
738Phosphothreonine(PKC)HMM predict
744Phosphoserine(PKG)HMM predict
759Phosphoserine(IKK)HMM predict
759Phosphoserine(PKA)HMM predict
759Phosphoserine(PKG)HMM predict
776Phosphoserine(CK1)HMM predict
780Phosphoserine(CK1)HMM predict
782Phosphoserine(PKB)HMM predict
782Phosphoserine(PKA)HMM predict
782Phosphoserine(IKK)HMM predict
782Phosphoserine(CK1)HMM predict
807Phosphothreonine(PKA)HMM predict
809Phosphoserine(IKK)HMM predict
846Phosphoserine(CDC2)HMM predict
900Phosphoserine(PKG)HMM predict
900Phosphoserine(IKK)HMM predict
902Phosphoserine(IKK)HMM predict
902Phosphoserine(CDC2)HMM predict
906Phosphoserine(CK1)HMM predict
906Phosphoserine(ATM)HMM predict
914Phosphotyrosine(SRC)HMM predict
938N-linkedHMM predict
958S-palmitoylHMM predict
1039Phosphothreonine(CDK)HMM predict
1070Phosphoserine(ATM)HMM predict
1091O-linkedHMM predict
1133Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_139244
  • Location:chr6 147566567-147748583
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 147564839 147565974 1135 1161
FOXA1 MCF7GSE15244 147555138 147555984 846 11007
Fos K562GSE19551 147564753 147566548 1795 917
FoxA1 MCF7MACSdata 147555046 147555491 445 11299
H3K4me3 colorectalcancer 147565379 147566516 1137 620
H3ac HepG2E 147565343 147566446 1103 673
LIN9 G0GSE7516 147565084 147565661 577 1195
P300 T0-glioblastomaGSE21026 147564999 147565787 788 1175
PolII HeLaGSE12783 147564744 147567976 3232 208
TAF k562GSE8489 147560092 147560645 553 6199
TAF k562GSE8489 147564682 147566370 1688 1042
TFAP2C MCF7GSE21234 147555034 147555719 685 11191
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 147762944 147762998 54 14388
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 147735074 147735401 327 0
CTCF CD4GSE12889 147647980 147648299 319 0
CTCF CD4SISSRdata 147647980 147648299 319 0
CTCF G2GSE9613 147566858 147567495 637 0
Oct1 H2O2-HelaGSE14283 147625423 147625450 27 0
P300 T0-glioblastomaGSE21026 147735074 147735291 217 0
RNAII Tamoxifen-MCF7GSE14664 147574564 147574664 100 0
Rb shRbSenescenceGSE19898 147623110 147623281 171 0
TAF k562GSE8489 147567570 147573039 5469 0
TFAP2C MCF7GSE21234 147650660 147651221 561 0
hScc1 BcellGSE12603 147566858 147567316 458 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
23291 mRNA STXBP5 chr6 147566567 147748584 202 mRNA chr6 147205942 147567443Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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