AutismKB 2.0

Annotation Detail for ADORA2A


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Basic Information Top
Gene Symbol:ADORA2A ( ADORA2,RDC8,hA2aR )
Gene Full Name: adenosine A2a receptor
Band: 22q11.23
Quick LinksEntrez ID:135; OMIM: 102776; Uniprot ID:AA2AR_HUMAN; ENSEMBL ID: ENSG00000100014,ENSG00000128271; HGNC ID: 263
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
154N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
154N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
9Phosphotyrosine(EGFR)HMM predict
39N-linkedHMM predict
42N-linkedHMM predict
103Phosphotyrosine(Jak)HMM predict
213Phosphoserine(ATM)HMM predict
223Phosphoserine(PKG)HMM predict
224Phosphothreonine(PKC)HMM predict
259S-palmitoylHMM predict
319Phosphothreonine(PKC)HMM predict
329Phosphoserine(CK2)HMM predict
348N-linkedHMM predict
374Phosphoserine(IKK)HMM predict
399GlycineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000675
  • Location:chr22 23159091-23168323
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 23151741 23154881 3140 5781
hScc1 BcellGSE12603 23153757 23154250 493 5088
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 23171492 23171756 264 3301
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 23159776 23162294 2518 0
NFkBII GM12878GSE19485 23159580 23161443 1863 0
TFAP2C MCF7GSE21234 23163750 23164312 562 0
TFAP2C MCF7GSE21234 23167029 23167879 850 0
hScc1 BcellGSE12603 23159189 23159786 597 0
hScc1 BcellGSE12603 23166971 23167415 444 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
17259 mRNA ADORA2A chr22 23153645 23162878 150 EST chr22 23158809 23162663Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018