AutismKB 2.0

Annotation Detail for ADORA2B


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Basic Information Top
Gene Symbol:ADORA2B ( ADORA2 )
Gene Full Name: adenosine A2b receptor
Band: 17p12
Quick LinksEntrez ID:136; OMIM: 600446; Uniprot ID:AA2BR_HUMAN; ENSEMBL ID: ENSG00000170425; HGNC ID: 264
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
153N-linked (GlcNAc...) (Potential).
163N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
153N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
163N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
311S-palmitoyl cysteine (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
10Phosphotyrosine(Jak)HMM predict
40Phosphothreonine(MAPK)HMM predict
104Phosphotyrosine(Jak)HMM predict
153N-linkedHMM predict
163N-linkedHMM predict
225Phosphothreonine(PKC)HMM predict
317SerineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000676
  • Location:chr17 15788955-15819934
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
RARA MCF7GSE15244 15770035 15770717 682 18580
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 15802772 15803933 1161 0
CTCF CD4GSE12889 15789184 15789352 168 0
CTCF CD4SISSRdata 15789184 15789352 168 0
CTCF G2GSE9613 15788678 15789528 850 0
Gata2 K562GSE18868 15800092 15800594 502 0
Gata2 K562GSE18868 15802820 15803455 635 0
H3ac HepG2E 15790602 15792214 1612 0
Myc K562GSE19551 15796023 15796367 344 0
Oct1 HelaGSE14283 15807121 15807148 27 0
P300 T30-glioblastomaGSE21026 15802660 15803965 1305 0
RARA MCF7GSE15244 15801122 15801670 548 0
RARA MCF7GSE15244 15807479 15808216 737 0
RARG MCF7GSE15244 15801339 15801742 403 0
Rb shRbSenescenceGSE19898 15789219 15789429 210 0
SRF HelaGSE8489 15816440 15817466 1026 0
TFAP2C MCF7GSE21234 15791287 15792839 1552 0
TFAP2C MCF7GSE21234 15807748 15808435 687 0
TFAP2C MCF7GSE21234 15817001 15817567 566 0
hScc1 BcellGSE12603 15788543 15789601 1058 0
hScc1 CdLSGSE12603 15788648 15789743 1095 0
p130 QuiescentGSE19898 15789409 15789615 206 0
p130 QuiescentGSE19898 15789935 15790090 155 0
p130 SenescentGSE19898 15789309 15789530 221 0
p130 SenescentGSE19898 15789917 15790228 311 0
p130 shRbQuiescentGSE19898 15789909 15790145 236 0
p130 shRbSenescentGSE19898 15789324 15789635 311 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-128 hsa-mir-128-1 2 20388705
hsa-miR-128 hsa-mir-128-2 3 20388705
hsa-miR-27a hsa-mir-27a 19 20388705
hsa-miR-27a* hsa-mir-27a 19 20388705
hsa-miR-27b hsa-mir-27b 9 20388705
hsa-miR-27b* hsa-mir-27b 9 20388705
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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