AutismKB 2.0

Annotation Detail for CPE


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Basic Information Top
Gene Symbol:CPE ( - )
Gene Full Name: carboxypeptidase E
Band: 4q32.3
Quick LinksEntrez ID:1363; OMIM: 114855; Uniprot ID:CBPE_HUMAN; ENSEMBL ID: ENSG00000109472; HGNC ID: 2303
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
139N-linked (GlcNAc...) (Potential).
390N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
139N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
390N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
78Phosphothreonine(PKC)HMM predict
139N-linkedHMM predict
144N-linkedHMM predict
167Phosphoserine(ATM)HMM predict
269Phosphotyrosine(Jak)HMM predict
271Phosphoserine(CK2)HMM predict
272Phosphoserine(CDC2)HMM predict
272Phosphoserine(ATM)HMM predict
390N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001873
  • Location:chr4 166519543-166638925
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog hESGSE18292 166508901 166509110 209 10538
RUNX JurkatGSE17954 166505879 166505968 89 13620
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF-mono JurkatQuESTdata 166657886 166658104 218 19070
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 166605385 166605717 332 0
CTCF CD4GSE12889 166634001 166634183 182 0
CTCF CD4SISSRdata 166605385 166605717 332 0
CTCF CD4SISSRdata 166634001 166634183 182 0
CTCF G2GSE9613 166519347 166520019 672 0
CTCF G2GSE9613 166557256 166557419 163 0
CTCF G2GSE9613 166571600 166571920 320 0
CTCF G2GSE9613 166605404 166605770 366 0
CTCF G2GSE9613 166633895 166634337 442 0
ER MCF7GSE19013 166562963 166563431 468 0
FOXA1 MCF7GSE15244 166574327 166574666 339 0
FOXA1 eGFPGSE10845 166574327 166574666 339 0
Fos K562GSE19551 166616981 166617708 727 0
FoxA1 MCF7MACSdata 166574166 166574443 277 0
H3ac HepG2E 166520318 166520841 523 0
Myc K562GSE19551 166617197 166617719 522 0
TAF HelaGSE8489 166559696 166559930 234 0
TFAP2C MCF7GSE21234 166581026 166581642 616 0
hScc1 BcellGSE12603 166605367 166605770 403 0
hScc1 BcellGSE12603 166633938 166634266 328 0
hScc1 CdLSGSE12603 166604810 166605917 1107 0
hScc1 G2GSE9613 166605367 166605770 403 0
hScc1 G2GSE9613 166633938 166634472 534 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018