Annotation Detail for LYPD2

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Basic Information Top

Gene Symbol:	LYPD2 ( LYPDC2,MGC148106,UNQ430 )
Gene Full Name:	LY6/PLAUR domain containing 2
Band:	8q24.3
Quick Links	Entrez ID:137797; OMIM: NA; Uniprot ID:LYPD2_HUMAN; ENSEMBL ID: ENSG00000197353; HGNC ID: 25215
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:1 results
Experimental PTM Sites from dbPTM:2 results
Predicted PTM Sites by profile HMM from dbPTM:7 results

Location(AA)	Modification
46	N-linked (GlcNAc...) (Potential).

Location(AA)	Modification	Resource
42	O-linked	HMM predict
46	N-linked	HMM predict
48	O-linked	HMM predict
72	Phosphoserine(IKK)	HMM predict
75	Phosphoserine(IKK)	HMM predict
92	Phosphoserine(IKK)	HMM predict
125	Leucine	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_205545
Location:chr8 143828630-143830953
strand:-

Upstream the gene:8 results
Downstream the gene:1 results
Inside the gene:3 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
H3ac	HepG2	E	143832961	143833545	584	2300
RARA	MCF7	GSE15244	143832961	143833545	584	2300
RARA	MCF7	GSE15244	143835509	143835814	305	4708
RARG	MCF7	GSE15244	143832961	143833609	648	2332
RARG	MCF7	GSE15244	143835483	143835840	357	4708
TFAP2C	MCF7	GSE21234	143835004	143835925	921	4511
USF1	HepG2	E	143832793	143833572	779	2229
hScc1	Bcell	GSE12603	143834722	143835267	545	4041

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
NRSF	pAb	Jurkat	143827510	143827972	462	890

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
NRSF	pAb	Jurkat	143828646	143829558	912	0
NRSF	pAb	Jurkat	143830378	143831377	999	0
hScc1	Bcell	GSE12603	143830306	143831265	959	0

Validated miRNA targets

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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