AutismKB 2.0

Annotation Detail for CR1


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Basic Information Top
Gene Symbol:CR1 ( C3BR,C4BR,CD35,KN )
Gene Full Name: complement component (3b/4b) receptor 1 (Knops blood group)
Band: 1q32.2
Quick LinksEntrez ID:1378; OMIM: 120620; Uniprot ID:CR1_HUMAN; ENSEMBL ID: ENSG00000203710; HGNC ID: 2334
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
42Pyrrolidone carboxylic acid (Potential).
56N-linked (GlcNAc...) (Potential).
252N-linked (GlcNAc...) (Potential).
410N-linked (GlcNAc...) (Potential).
447N-linked (GlcNAc...) (Potential).
509N-linked (GlcNAc...) (Potential).
578N-linked (GlcNAc...) (Potential).
702N-linked (GlcNAc...) (Potential).
860N-linked (GlcNAc...) (Potential).
897N-linked (GlcNAc...) (Potential).
959N-linked (GlcNAc...) (Potential).
1028N-linked (GlcNAc...) (Potential).
1152N-linked (GlcNAc...) (Potential).
1310N-linked (GlcNAc...) (Potential).
1481N-linked (GlcNAc...) (Potential).
1504N-linked (GlcNAc...) (Potential).
1534N-linked (GlcNAc...) (Potential).
1540N-linked (GlcNAc...) (Potential).
1605N-linked (GlcNAc...) (Potential).
1763N-linked (GlcNAc...) (Potential).
1908N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
42Pyrrolidone carboxylic acid (Potential).Swiss-Prot 53.0
56N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
252N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
410N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
447N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
509N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
578N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
702N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
860N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
897N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
959N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1028N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1152N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1310N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1481N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1504N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1534N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1540N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1605N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1763N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1908N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
5Phosphoserine(CDC2)HMM predict
5Phosphoserine(CDK)HMM predict
8Phosphoserine(CDC2)HMM predict
8O-linkedHMM predict
8Phosphoserine(MAPK)HMM predict
56N-linkedHMM predict
156N-linkedHMM predict
239Phosphothreonine(CDC2)HMM predict
252N-linkedHMM predict
294O-linkedHMM predict
309Phosphothreonine(PKC)HMM predict
347Phosphoserine(IKK)HMM predict
410N-linkedHMM predict
447N-linkedHMM predict
482Phosphoserine(CDC2)HMM predict
509N-linkedHMM predict
578N-linkedHMM predict
689Phosphothreonine(CDC2)HMM predict
702N-linkedHMM predict
744O-linkedHMM predict
759Phosphothreonine(PKC)HMM predict
797Phosphoserine(IKK)HMM predict
860N-linkedHMM predict
897N-linkedHMM predict
932Phosphoserine(CDC2)HMM predict
959N-linkedHMM predict
1028N-linkedHMM predict
1139Phosphothreonine(CDC2)HMM predict
1152N-linkedHMM predict
1194O-linkedHMM predict
1209Phosphothreonine(MAPK)HMM predict
1217Phosphoserine(ATM)HMM predict
1241Phosphothreonine(CDC2)HMM predict
1310N-linkedHMM predict
1311N-linkedHMM predict
1335Phosphothreonine(PKA)HMM predict
1382Phosphoserine(CDC2)HMM predict
1406Phosphoserine(CDC2)HMM predict
1474O-linkedHMM predict
1493Phosphoserine(CDC2)HMM predict
1504N-linkedHMM predict
1534N-linkedHMM predict
1540N-linkedHMM predict
1605N-linkedHMM predict
1670Phosphoserine(ATM)HMM predict
1694Phosphothreonine(CDC2)HMM predict
1763N-linkedHMM predict
1835Phosphoserine(CDC2)HMM predict
1908N-linkedHMM predict
1935Phosphothreonine(PKC)HMM predict
1950Phosphoserine(IKK)HMM predict
2017Phosphoserine(CAMK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000573
  • Location:chr1 205736095-205881731
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 205733180 205734880 1700 2066
H3K27me3 colorectalcancer 205735441 205736231 790 260
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 205898403 205898761 358 16851
Fos K562GSE19551 205884671 205885600 929 3404
H3ac HepG2E 205885627 205885862 235 4013
TAF k562GSE8489 205885471 205886371 900 4190
TAF k562GSE8489 205886712 205887552 840 5401
TAF k562GSE8489 205888206 205890561 2355 7652
hScc1 BcellGSE12603 205885124 205885828 704 3745
hScc1 BcellGSE12603 205898403 205899211 808 17076
p130 QuiescentGSE19898 205884978 205885209 231 3362
p130 SenescentGSE19898 205884968 205885222 254 3364
p130 shRbQuiescentGSE19898 205884993 205885345 352 3438
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 205739527 205739793 266 0
CTCF CD4SISSRdata 205739527 205739793 266 0
CTCF G2GSE9613 205768116 205768868 752 0
CTCF G2GSE9613 205786819 205787461 642 0
CTCF G2GSE9613 205805272 205805840 568 0
CTCF G2GSE9613 205819142 205819340 198 0
ER MCF7GSE19013 205768004 205768802 798 0
Gata1 K562GSE18868 205760151 205760599 448 0
Gata2 K562GSE18868 205760043 205760667 624 0
Gata2 K562GSE18868 205866060 205866700 640 0
Gata2 K562GSE18868 205875327 205876104 777 0
Myc K562GSE19551 205760048 205760659 611 0
Myc K562GSE19551 205819399 205819717 318 0
Myc K562GSE19551 205866119 205866824 705 0
P300 T30-glioblastomaGSE21026 205843688 205844269 581 0
STAT1 IFNSISSRdata 205819126 205819913 787 0
TAF k562GSE8489 205789590 205789743 153 0
hScc1 BcellGSE12603 205768222 205768906 684 0
hScc1 BcellGSE12603 205786777 205787423 646 0
hScc1 BcellGSE12603 205805119 205805974 855 0
hScc1 CdLSGSE12603 205768298 205768906 608 0
hScc1 CdLSGSE12603 205786610 205787461 851 0
hScc1 CdLSGSE12603 205805308 205805974 666 0
hScc1 CdLSGSE12603 205819105 205819340 235 0
hScc1 G2GSE9613 205768055 205768802 747 0
hScc1 G2GSE9613 205786853 205787357 504 0
p63 keratinocytesGSE17611 205846032 205846819 787 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
2258 mRNA CR1 chr1 204057896 204202381 280 EST chr1 204095109 204096164Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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