AutismKB 2.0

Annotation Detail for CREM


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Basic Information Top
Gene Symbol:CREM ( ICER,MGC111110,MGC17881,MGC41893,hCREM-2 )
Gene Full Name: cAMP responsive element modulator
Band: 10p11.21
Quick LinksEntrez ID:1390; OMIM: 123812; Uniprot ID:CREM_HUMAN; ENSEMBL ID: ENSG00000095794; HGNC ID: 2352
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
136Phosphoserine (By similarity).
145Phosphoserine (By similarity).
287Phosphoserine.
290Phosphoserine.
293Phosphoserine.
Location(AA) Modifications Resource
116PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
19Phosphothreonine(PKC)HMM predict
42O-linkedHMM predict
48Phosphothreonine(PKC)HMM predict
52Phosphoserine(CDC2)HMM predict
99Phosphoserine(CK2)HMM predict
102Phosphoserine(CK1)HMM predict
120Phosphoserine(PKC)HMM predict
120Phosphoserine(PKB)HMM predict
120PhosphoserineHMM predict
120Phosphoserine(PKA)HMM predict
121PhosphotyrosineHMM predict
143Phosphoserine(CK2)HMM predict
143Phosphoserine(CK1)HMM predict
143PhosphoserineHMM predict
151Phosphoserine(IKK)HMM predict
151O-linkedHMM predict
154O-linkedHMM predict
274Phosphoserine(IKK)HMM predict
334Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001881
  • Location:chr10 35455806-35508779
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 35449323 35449564 241 6363
CTCF CD4SISSRdata 35449323 35449564 241 6363
Oct1 H2O2-HelaGSE14283 35440446 35440489 43 15339
Oct1 HelaGSE14283 35440445 35440488 43 15340
Oct1 HelaGSE14283 35441448 35441485 37 14340
PHF8 293TGSE20725 35454950 35456407 1457 128
hScc1 BcellGSE12603 35449332 35449516 184 6383
hScc1 CdLSGSE12603 35448825 35449516 691 6636
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 35457072 35457421 349 0
H3ac HepG2E 35457072 35457421 349 0
NFkBII GM15510GSE19485 35455001 35456965 1964 0
PHF8 HeLaGSE20725 35455253 35456833 1580 0
PHF8 Hs68minusFBSGSE20725 35455452 35457121 1669 0
PHF8 Hs68plusFBSGSE20725 35455079 35457109 2030 0
TAF HelaGSE8489 35457072 35457421 349 0
TAF k562GSE8489 35456539 35456748 209 0
TAF k562GSE8489 35457072 35457421 349 0
TAF k562GSE8489 35457766 35458638 872 0
hScc1 BcellGSE12603 35455491 35456539 1048 0
hScc1 BcellGSE12603 35478247 35478788 541 0
hScc1 CdLSGSE12603 35455491 35456559 1068 0
hScc1 CdLSGSE12603 35461162 35461383 221 0
hScc1 CdLSGSE12603 35478211 35478788 577 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-34b hsa-mir-34b 11 19960054
hsa-miR-34b* hsa-mir-34b 11 19960054
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
2999 mRNA CREM chr10 35455806 35508780 153 EST chr10 35429831 35456008Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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