AutismKB 2.0

Annotation Detail for CRH


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Basic Information Top
Gene Symbol:CRH ( CRF )
Gene Full Name: corticotropin releasing hormone
Band: 8q13.1
Quick LinksEntrez ID:1392; OMIM: 122560; Uniprot ID:CRF_HUMAN; ENSEMBL ID: ENSG00000147571; HGNC ID: 2355
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
194Isoleucine amide.
Location(AA) Modifications Resource
194Isoleucine amide (G-195 provides amidegroup).Swiss-Prot 53.0
Location(AA) Modification Resource
19S-palmitoylHMM predict
80N-linkedHMM predict
82Phosphoserine(CDC2)HMM predict
82Phosphoserine(CDK)HMM predict
88Phosphoserine(MAPK)HMM predict
88Phosphoserine(ATM)HMM predict
88Phosphoserine(IKK)HMM predict
194IsoleucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000756
  • Location:chr8 67251172-67253251
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 67271580 67271772 192 18425
CTCF CD4SISSRdata 67271580 67271772 192 18425
NRSF mAbJurkat 67252155 67255435 3280 544
NRSF pAbJurkat 67251882 67254933 3051 156
Nanog hESGSE18292 67261379 67261985 606 8431
Sox2 hESGSE18292 67261281 67261759 478 8269
Stat6 IL-4-hr4GSE17850 67269254 67269841 587 16296
TFAP2C MCF7GSE21234 67265491 67266106 615 12547
TFAP2C MCF7GSE21234 67270304 67270862 558 17332
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 67251744 67251964 220 0
CTCF CD4SISSRdata 67251744 67251964 220 0
CTCF G2GSE9613 67251742 67252553 811 0
NRSF JurkatGSE13047 67251522 67254015 2493 0
NRSF-mono JurkatQuESTdata 67251662 67253547 1885 0
NRSF-poly JurkatQuESTdata 67251639 67253957 2318 0
hScc1 BcellGSE12603 67251778 67252655 877 0
hScc1 CdLSGSE12603 67251549 67252553 1004 0
hScc1 G2GSE9613 67251708 67252590 882 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018