Annotation Detail for CRK
Basic Information Top
| Gene Symbol: | CRK ( CRKII ) |
|---|---|
| Gene Full Name: | v-crk sarcoma virus CT10 oncogene homolog (avian) |
| Band: | 17p13.3 |
| Quick Links | Entrez ID:1398; OMIM: 164762; Uniprot ID:CRK_HUMAN; ENSEMBL ID: ENSG00000167193; HGNC ID: 2362 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 2 | N-acetylalanine. | |
| 41 | Phosphoserine (By similarity). | |
| 42 | Phosphothreonine (By similarity). | |
| 74 | Phosphoserine. | |
| 83 | Phosphoserine. | |
| 136 | Phosphotyrosine. | |
| 221 | Phosphotyrosine. | |
| 239 | Phosphotyrosine. | |
| 251 | Phosphotyrosine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 41 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
| 42 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 |
| 221 | Phosphotyrosine. | Swiss-Prot 53.0 |
| 221 | Phosphotyrosine (Abl;EGFR;IGF) | Phospho.ELM 6.0 |
| 239 | Phosphotyrosine. | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 19 | Phosphoserine(PKG) | HMM predict |
| 63 | N-linked | HMM predict |
| 74 | O-linked | HMM predict |
| 74 | Phosphoserine(CDC2) | HMM predict |
| 74 | Phosphoserine(IKK) | HMM predict |
| 83 | Phosphoserine(CDC2) | HMM predict |
| 136 | Phosphotyrosine(EGFR) | HMM predict |
| 196 | Phosphoserine(IKK) | HMM predict |
| 221 | Phosphotyrosine(INSR) | HMM predict |
| 221 | Phosphotyrosine(Abl) | HMM predict |
| 225 | O-linked | HMM predict |
| 228 | Phosphothreonine(CDK) | HMM predict |
| 239 | Phosphotyrosine(EGFR) | HMM predict |
| 270 | N-linked | HMM predict |
| 283 | Methylarginine | HMM predict |
- RefSeq ID: NM_016823
- Location:chr17 1272209-1306293
- strand:-
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| NFkBII | GM18526 | GSE19485 | 1305797 | 1306956 | 1159 | 83 |
| P300 | T0-glioblastoma | GSE21026 | 1306057 | 1306752 | 695 | 111 |
| PHF8 | 293T | GSE20725 | 1305719 | 1306985 | 1266 | 59 |
| Rb | Senescent | GSE19898 | 1306115 | 1306591 | 476 | 60 |
| p130 | Senescent | GSE19898 | 1306064 | 1306741 | 677 | 109 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| ETS1 | Jurkat | GSE17954 | 1305764 | 1306722 | 958 | 0 |
| FoxA1 | MCF7 | MACSdata | 1299594 | 1299691 | 97 | 0 |
| H3K4me2 | HCT116 | GSE10453 | 1304585 | 1305356 | 771 | 0 |
| H3K4me3 | colorectal | cancer | 1304880 | 1305394 | 514 | 0 |
| H3ac | HepG2 | E | 1304622 | 1305719 | 1097 | 0 |
| NFkBII | GM12892 | GSE19485 | 1281258 | 1282397 | 1139 | 0 |
| NFkBII | GM15510 | GSE19485 | 1305611 | 1306844 | 1233 | 0 |
| P300 | T30-glioblastoma | GSE21026 | 1304964 | 1306887 | 1923 | 0 |
| PHF8 | HeLa | GSE20725 | 1305455 | 1307117 | 1662 | 0 |
| RARG | MCF7 | GSE15244 | 1304657 | 1305308 | 651 | 0 |
| Rb | Growing | GSE19898 | 1305312 | 1305580 | 268 | 0 |
| Rb | Senescent | GSE19898 | 1272933 | 1273294 | 361 | 0 |
| hScc1 | Bcell | GSE12603 | 1305308 | 1306272 | 964 | 0 |
| p130 | Quiescent | GSE19898 | 1273059 | 1273226 | 167 | 0 |
| p130 | Senescent | GSE19898 | 1272940 | 1273466 | 526 | 0 |
| p130 | shRbSenescent | GSE19898 | 1273220 | 1273453 | 233 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-miR-126 | hsa-mir-126 | 9 | 19767772 |
| hsa-miR-126 | hsa-mir-126 | 9 | 18602365 |
| hsa-miR-126* | hsa-mir-126 | 9 | 19767772 |
| hsa-miR-126* | hsa-mir-126 | 9 | 18602365 |
| hsa-miR-218 | hsa-mir-218-1 | 4 | 19767772 |
| hsa-miR-218 | hsa-mir-218-2 | 5 | 19767772 |
| hsa-miR-224 | hsa-mir-224 | X | 19767772 |
| No data |
Cis-Nats regulation