Annotation Detail for CRKL
Basic Information Top
| Gene Symbol: | CRKL ( - ) |
|---|---|
| Gene Full Name: | v-crk sarcoma virus CT10 oncogene homolog (avian)-like |
| Band: | 22q11.21 |
| Quick Links | Entrez ID:1399; OMIM: 602007; Uniprot ID:CRKL_HUMAN; ENSEMBL ID: ENSG00000099942; HGNC ID: 2363 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 107 | Phosphoserine (By similarity). | |
| 127 | Phosphotyrosine. | |
| 132 | Phosphotyrosine. | |
| 198 | Phosphotyrosine. | |
| 207 | Phosphotyrosine. | |
| 251 | Phosphotyrosine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 107 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
| 207 | Phosphotyrosine. | Swiss-Prot 53.0 |
| 207 | Phosphotyrosine (Abl) | Phospho.ELM 6.0 |
| 251 | Phosphotyrosine. | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 8 | Phosphoserine(PKA) | HMM predict |
| 26 | O-linked | HMM predict |
| 107 | O-linked | HMM predict |
| 185 | Phosphoserine(CDC2) | HMM predict |
| 207 | Phosphotyrosine(Abl) | HMM predict |
| 212 | O-linked | HMM predict |
| 213 | O-linked | HMM predict |
| 214 | O-linked | HMM predict |
| 220 | O-linked | HMM predict |
| 222 | Phosphoserine(CDC2) | HMM predict |
| 228 | Phosphothreonine(MAPK) | HMM predict |
| 228 | Phosphothreonine(CDK) | HMM predict |
| 228 | O-linked | HMM predict |
- RefSeq ID: NM_005207
- Location:chr22 19601713-19637888
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CBP | T30-glioblastoma | GSE21026 | 19588558 | 19589412 | 854 | 12729 |
| ER | MCF7 | GSE19013 | 19600793 | 19601701 | 908 | 467 |
| ETS1 | Jurkat | GSE17954 | 19601098 | 19602145 | 1047 | 92 |
| H3ac | HepG2 | E | 19600989 | 19601279 | 290 | 580 |
| HIF1 | Hypo | HepG2 | 19600989 | 19601592 | 603 | 423 |
| LIN9 | G0 | GSE7516 | 19600989 | 19601486 | 497 | 476 |
| Nanog | ES | GSE20650 | 19595407 | 19595529 | 122 | 6246 |
| Oct4 | ES | GSE20650 | 19595376 | 19595520 | 144 | 6266 |
| P300 | T0-glioblastoma | GSE21026 | 19588913 | 19589524 | 611 | 12495 |
| P300 | T30-glioblastoma | GSE21026 | 19588565 | 19589665 | 1100 | 12599 |
| RARA | MCF7 | GSE15244 | 19588748 | 19589768 | 1020 | 12456 |
| RARA | MCF7 | GSE15244 | 19600989 | 19601279 | 290 | 580 |
| RARG | MCF7 | GSE15244 | 19588785 | 19589404 | 619 | 12619 |
| RARG | MCF7 | GSE15244 | 19600989 | 19601243 | 254 | 598 |
| STAT1 | IFN | SISSRdata | 19601001 | 19601802 | 801 | 312 |
| TFAP2C | MCF7 | GSE21234 | 19600974 | 19601636 | 662 | 409 |
| p130 | Quiescent | GSE19898 | 19600962 | 19601180 | 218 | 643 |
| p130 | Senescent | GSE19898 | 19601038 | 19601819 | 781 | 285 |
| p130 | shRbQuiescent | GSE19898 | 19601187 | 19601463 | 276 | 389 |
| p130 | shRbSenescent | GSE19898 | 19601106 | 19601948 | 842 | 187 |
| p63 | keratinocytes | GSE17611 | 19588614 | 19589485 | 871 | 12664 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| FOXA1 | MCF7 | GSE15244 | 19642438 | 19642708 | 270 | 4685 |
| RARA | MCF7 | GSE15244 | 19642508 | 19642708 | 200 | 4720 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 19601207 | 19602348 | 1141 | 0 |
| FOXA1 | MCF7 | GSE15244 | 19621475 | 19621890 | 415 | 0 |
| FOXA1 | MCF7 | GSE15244 | 19635014 | 19635294 | 280 | 0 |
| H3K4me3 | colorectal | cancer | 19602277 | 19602845 | 568 | 0 |
| H3K4me3 | colorectal | cancer | 19603268 | 19603905 | 637 | 0 |
| H3ac | HepG2 | E | 19602382 | 19602845 | 463 | 0 |
| H3ac | HepG2 | E | 19603268 | 19604396 | 1128 | 0 |
| H3ac | HepG2 | E | 19604809 | 19605333 | 524 | 0 |
| H3ac | HepG2 | E | 19606608 | 19606934 | 326 | 0 |
| PHF8 | HeLa | GSE20725 | 19601147 | 19602564 | 1417 | 0 |
| PHF8 | Hs68plusFBS | GSE20725 | 19601482 | 19602524 | 1042 | 0 |
| RARG | MCF7 | GSE15244 | 19621439 | 19621925 | 486 | 0 |
| RARG | MCF7 | GSE15244 | 19635014 | 19635330 | 316 | 0 |
| SRF | GMO | GSE8489 | 19631269 | 19631504 | 235 | 0 |
| TAF | k562 | GSE8489 | 19602313 | 19602845 | 532 | 0 |
| VDR | GM10861-Unstim | GSE22484 | 19600933 | 19602555 | 1622 | 0 |
| hScc1 | Bcell | GSE12603 | 19601064 | 19602483 | 1419 | 0 |
Validated miRNA targets| Cluster ID | Plue Type | Plus Gene Name | Plus Chromosome | Plus Start | Plus End | Overlap Length | Minus Type | Minus Gene Name | Minus Chromosome | Minus Star | Minus End | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 17177 | mRNA | CRKL | chr22 | 19596267 | 19632443 | 68 | mRNA | chr22 | 19632375 | 19636656 | Sense/Antisense (SA) pairs | |