AutismKB 2.0

Annotation Detail for CRY2


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Basic Information Top
Gene Symbol:CRY2 ( FLJ10332,HCRY2,KIAA0658,PHLL2 )
Gene Full Name: cryptochrome 2 (photolyase-like)
Band: 11p11.2
Quick LinksEntrez ID:1408; OMIM: 603732; Uniprot ID:CRY2_HUMAN; ENSEMBL ID: ENSG00000121671; HGNC ID: 2385
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
266Phosphoserine; by MAPK (By similarity).
558Phosphoserine; by MAPK (By similarity).
Location(AA) Modifications Resource
266Phosphoserine (by MAPK) (By similarity).Swiss-Prot 53.0
558Phosphoserine (by MAPK) (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
19O-linkedHMM predict
119SulfotyrosineHMM predict
209PhosphotyrosineHMM predict
209Phosphotyrosine(Syk)HMM predict
209Phosphotyrosine(INSR)HMM predict
266Phosphoserine(CDK)HMM predict
266Phosphoserine(MAPK)HMM predict
266Phosphoserine(CDC2)HMM predict
278S-palmitoylHMM predict
298N-linkedHMM predict
300Phosphothreonine(PKA)HMM predict
441Phosphothreonine(PKA)HMM predict
507Phosphotyrosine(EGFR)HMM predict
539Phosphoserine(ATM)HMM predict
539Phosphoserine(CK1)HMM predict
539O-linkedHMM predict
543Phosphoserine(IKK)HMM predict
554O-linkedHMM predict
554O-linkedHMM predict
558Phosphoserine(CDK)HMM predict
558Phosphoserine(CDK)HMM predict
558Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_021117
  • Location:chr11 45825604-45861371
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 45821334 45821667 333 4104
CTCF CD4SISSRdata 45821334 45821667 333 4104
FOXA1 MCF7GSE15244 45821263 45821803 540 4072
NRSF pAbJurkat 45810781 45811004 223 14712
Oct1 H2O2-HelaGSE14283 45808449 45808490 41 17135
Oct1 HelaGSE14283 45808449 45808492 43 17134
Oct1 HelaGSE14283 45809932 45809992 60 15643
RARA MCF7GSE15244 45821300 45821839 539 4035
Rb GrowingGSE19898 45821311 45821632 321 4133
Rb QuiescentGSE19898 45821328 45821589 261 4146
Rb SenescentGSE19898 45821254 45821531 277 4212
hScc1 BcellGSE12603 45821263 45821581 318 4183
hScc1 BcellGSE12603 45825183 45825552 369 237
hScc1 CdLSGSE12603 45821263 45821658 395 4144
hScc1 G2GSE9613 45821263 45821694 431 4126
p130 QuiescentGSE19898 45821432 45821797 365 3990
p130 SenescentGSE19898 45821355 45821636 281 4109
p130 shRbSenescentGSE19898 45821412 45821749 337 4024
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 45850953 45851118 165 0
CTCF CD4SISSRdata 45850953 45851118 165 0
FOXA1 MCF7GSE15244 45826636 45827143 507 0
Fos K562GSE19551 45858126 45858848 722 0
GATA3 MCF7GSE15244 45840946 45841701 755 0
H3K4me3 colorectalcancer 45826519 45826820 301 0
KLF4 hESGSE17917 45825648 45826052 404 0
NRSF mAbJurkat 45858243 45863615 5372 0
NRSF pAbJurkat 45843955 45844331 376 0
Oct1 H2O2-HelaGSE14283 45836611 45836669 58 0
Oct1 HelaGSE14283 45836611 45836652 41 0
Oct1 HelaGSE14283 45840559 45840588 29 0
Oct1 HelaGSE14283 45845931 45845996 65 0
Oct1 HelaGSE14283 45850558 45850585 27 0
PHF8 293TGSE20725 45825166 45826397 1231 0
PHF8 HeLaGSE20725 45825185 45826125 940 0
PHF8 Hs68plusFBSGSE20725 45824608 45826635 2027 0
RARA MCF7GSE15244 45826492 45827631 1139 0
RARG MCF7GSE15244 45826636 45827252 616 0
TAF HelaGSE8489 45826711 45827491 780 0
hScc1 BcellGSE12603 45858894 45859560 666 0
hScc1 G2GSE9613 45850777 45851584 807 0
p130 QuiescentGSE19898 45825877 45826269 392 0
p130 SenescentGSE19898 45825308 45826253 945 0
p130 shRbQuiescentGSE19898 45825667 45826172 505 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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