AutismKB 2.0

Annotation Detail for SESN3


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Basic Information Top
Gene Symbol:SESN3 ( MGC29667,SEST3 )
Gene Full Name: sestrin 3
Band: 11q21
Quick LinksEntrez ID:143686; OMIM: 607768; Uniprot ID:SESN3_HUMAN; ENSEMBL ID: ENSG00000149212; HGNC ID: 23060
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
7Phosphoserine(CDC2)HMM predict
54Phosphothreonine(PKC)HMM predict
68Phosphothreonine(PKC)HMM predict
74N-linkedHMM predict
92Phosphoserine(ATM)HMM predict
184N-linkedHMM predict
245N-linkedHMM predict
260Phosphoserine(CK1)HMM predict
282Phosphoserine(CK2)HMM predict
282Phosphoserine(ATM)HMM predict
282PhosphoserineHMM predict
312Phosphoserine(CK2)HMM predict
384N-linkedHMM predict
387Phosphotyrosine(INSR)HMM predict
388N-linkedHMM predict
422SulfotyrosineHMM predict
436Phosphotyrosine(Jak)HMM predict
441O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_144665
  • Location:chr11 94545780-94603893
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 94603773 94604608 835 297
Nanog hESGSE18292 94607913 94608596 683 4361
Oct1 H2O2-HelaGSE14283 94617165 94617193 28 13286
hScc1 BcellGSE12603 94604896 94605089 193 1099
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 94543149 94543183 34 2615
Gata1 K562GSE18868 94526002 94526763 761 19398
Gata2 K562GSE18868 94525591 94526865 1274 19553
NRSF pAbJurkat 94529064 94529199 135 16649
TFAP2C MCF7GSE21234 94527394 94527789 395 18189
hScc1 BcellGSE12603 94527354 94527867 513 18170
hScc1 CdLSGSE12603 94527354 94527867 513 18170
hScc1 G2GSE9613 94527354 94527867 513 18170
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 94596250 94596286 36 0
ER E2-MCF7GSE14664 94603161 94603193 32 0
H3K4me3 colorectalcancer 94602710 94603218 508 0
NRSF pAbJurkat 94603662 94604041 379 0
Oct1 H2O2-HelaGSE14283 94570884 94570923 39 0
Oct1 HelaGSE14283 94570884 94570922 38 0
Oct1 HelaGSE14283 94587429 94587457 28 0
hScc1 BcellGSE12603 94603296 94604183 887 0
hScc1 CdLSGSE12603 94603139 94604295 1156 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018