AutismKB 2.0

Annotation Detail for CSNK1E


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Basic Information Top
Gene Symbol:CSNK1E ( HCKIE,MGC10398 )
Gene Full Name: casein kinase 1, epsilon
Band: 22q13.1
Quick LinksEntrez ID:1454; OMIM: 600863; Uniprot ID:KC1E_HUMAN; ENSEMBL ID: ENSG00000213923; HGNC ID: 2453
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
323Phosphoserine.
343Phosphoserine.
350Phosphoserine.
351Phosphothreonine.
354Phosphoserine.
362Phosphothreonine.
363Phosphoserine.
389Phosphoserine.
391Phosphoserine.
405Phosphoserine.
407Phosphothreonine.
408Phosphoserine.
Location(AA) Modifications Resource
323Phosphoserine (CK1 epsilon;)Phospho.ELM 6.0
325Phosphothreonine (CK1 epsilon;)Phospho.ELM 6.0
334Phosphothreonine (CK1 epsilon;)Phospho.ELM 6.0
337Phosphothreonine (CK1 epsilon;)Phospho.ELM 6.0
362Phosphothreonine.Swiss-Prot 53.0
362PhosphothreoninePhospho.ELM 6.0
363PhosphoserinePhospho.ELM 6.0
363Phosphoserine.Swiss-Prot 53.0
368Phosphoserine (CK1 epsilon;)Phospho.ELM 6.0
405Phosphoserine (CK1 epsilon;)Phospho.ELM 6.0
407Phosphothreonine (CK1 epsilon;)Phospho.ELM 6.0
408Phosphoserine (CK1 epsilon;)Phospho.ELM 6.0
Location(AA) Modification Resource
56Phosphotyrosine(Syk)HMM predict
77Phosphotyrosine(SRC)HMM predict
77Phosphotyrosine(INSR)HMM predict
101Phosphoserine(PKG)HMM predict
101Phosphoserine(PKA)HMM predict
101Phosphoserine(PKA)HMM predict
172N-linkedHMM predict
201Phosphotyrosine(Jak)HMM predict
201Phosphotyrosine(INSR)HMM predict
350O-linkedHMM predict
351Phosphothreonine(CDK)HMM predict
351Phosphothreonine(MAPK)HMM predict
351Phosphothreonine(CDC2)HMM predict
351O-linkedHMM predict
354O-linkedHMM predict
361N-linkedHMM predict
363Phosphoserine(CDC2)HMM predict
387N-linkedHMM predict
389O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001894
  • Location:chr22 37016643-37044034
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 37043767 37044317 550 8
Nanog hESGSE18292 37051460 37051858 398 7625
P300 T30-glioblastomaGSE21026 37053580 37054495 915 10003
Rb QuiescentGSE19898 37044281 37044454 173 333
Sox2 hESGSE18292 37051456 37051851 395 7619
TFAP2C MCF7GSE21234 37043543 37044707 1164 91
hScc1 BcellGSE12603 37045229 37045733 504 1447
p130 SenescentGSE19898 37044212 37044631 419 387
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 37043471 37043698 227 0
p130 QuiescentGSE19898 37043518 37043764 246 0
p130 SenescentGSE19898 37043496 37043727 231 0
p130 shRbQuiescentGSE19898 37043413 37044174 761 0
p130 shRbSenescentGSE19898 37043420 37043978 558 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018