AutismKB 2.0

Annotation Detail for NRG4


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Basic Information Top
Gene Symbol:NRG4 ( DKFZp779N0541,DKFZp779N1944,HRG4 )
Gene Full Name: neuregulin 4
Band: 15q24.2
Quick LinksEntrez ID:145957; OMIM: 610894; Uniprot ID:NRG4_HUMAN; ENSEMBL ID: ENSG00000169752; HGNC ID: 29862
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
39N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
39N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
15Phosphoserine(IKK)HMM predict
39N-linkedHMM predict
104Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_138573
  • Location:chr15 74022899-74091839
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 74097641 74097680 39 5821
Oct1 HelaGSE14283 74097870 74097900 30 6046
Oct1 HelaGSE14283 74111576 74111605 29 19751
TFAP2C MCF7GSE21234 74103387 74104179 792 11944
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 74022880 74022916 36 2
ER Fulvestrant-MCF7GSE14664 74022878 74022915 37 3
Oct1 H2O2-HelaGSE14283 74022881 74022910 29 4
Oct1 HelaGSE14283 74022880 74022911 31 4
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 74044647 74045324 677 0
FOXA1 eGFPGSE10845 74044647 74045359 712 0
Myc K562GSE19551 74091640 74092023 383 0
PolII HeLaGSE12783 74089854 74092166 2312 0
STAT1 IFNSISSRdata 74065318 74065885 567 0
TAF HelaGSE8489 74091112 74091799 687 0
p63 keratinocytesGSE17611 74026237 74026966 729 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018