AutismKB 2.0

Annotation Detail for VCAN


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Basic Information Top
Gene Symbol:VCAN ( CSPG2,DKFZp686K06110,ERVR,GHAP,PG-M,WGN,WGN1 )
Gene Full Name: versican
Band: 5q14.2-q14.3
Quick LinksEntrez ID:1462; OMIM: 118661; Uniprot ID:CSPG2_HUMAN; ENSEMBL ID: ENSG00000038427; HGNC ID: 2464
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
57N-linked (GlcNAc...) (Potential).
330N-linked (GlcNAc...).
615N-linked (GlcNAc...) (Potential).
782N-linked (GlcNAc...) (Potential).
809N-linked (GlcNAc...) (Potential).
1332N-linked (GlcNAc...) (Potential).
1398N-linked (GlcNAc...) (Potential).
1442N-linked (GlcNAc...) (Potential).
1468N-linked (GlcNAc...) (Potential).
1663N-linked (GlcNAc...) (Potential).
1898N-linked (GlcNAc...) (Potential).
2112Phosphoserine.
2116Phosphoserine.
2179N-linked (GlcNAc...) (Potential).
2272N-linked (GlcNAc...) (Potential).
2280N-linked (GlcNAc...) (Potential).
2360N-linked (GlcNAc...) (Potential).
2385N-linked (GlcNAc...) (Potential).
2392N-linked (GlcNAc...) (Potential).
2496N-linked (GlcNAc...) (Potential).
2628N-linked (GlcNAc...) (Potential).
2934N-linked (GlcNAc...) (Potential).
3067N-linked (GlcNAc...) (Potential).
3369N-linked (GlcNAc...) (Potential).
3379N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
57N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
330N-linked (GlcNAc...).Swiss-Prot 53.0
615N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
782N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
809N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1332N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1398N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1442N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1468N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1663N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1898N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2179N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2272N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2280N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2360N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2385N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2392N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2496N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2628N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2934N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3067N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3369N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3379N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
29Phosphoserine(CDC2)HMM predict
57N-linkedHMM predict
102Phosphoserine(PKG)HMM predict
116Phosphothreonine(PKC)HMM predict
234Phosphoserine(CDC2)HMM predict
239Phosphotyrosine(Syk)HMM predict
279Phosphothreonine(PKC)HMM predict
296SulfotyrosineHMM predict
330N-linkedHMM predict
364Phosphoserine(MAPK)HMM predict
364Phosphoserine(CDK)HMM predict
364Phosphoserine(IKK)HMM predict
366O-linkedHMM predict
368Phosphoserine(CK1)HMM predict
421O-linkedHMM predict
425O-linkedHMM predict
425Phosphothreonine(MAPK)HMM predict
425PhosphothreonineHMM predict
429Phosphoserine(PKC)HMM predict
440Phosphoserine(IKK)HMM predict
483Phosphothreonine(PKC)HMM predict
500Phosphothreonine(PKC)HMM predict
516O-linkedHMM predict
518Phosphothreonine(MAPK)HMM predict
518Phosphothreonine(CDK)HMM predict
544Phosphothreonine(PKC)HMM predict
586O-linkedHMM predict
599Phosphoserine(CK1)HMM predict
599Phosphoserine(IKK)HMM predict
605Phosphothreonine(PKC)HMM predict
607Phosphoserine(CDC2)HMM predict
607Phosphoserine(IKK)HMM predict
615N-linkedHMM predict
617Phosphoserine(CK2)HMM predict
627Phosphothreonine(PKC)HMM predict
675O-linkedHMM predict
699SulfotyrosineHMM predict
716Phosphothreonine(CK2)HMM predict
729Phosphoserine(CK1)HMM predict
729Phosphoserine(IKK)HMM predict
773O-linkedHMM predict
773Phosphothreonine(MAPK)HMM predict
782N-linkedHMM predict
809N-linkedHMM predict
821O-linkedHMM predict
823O-linkedHMM predict
824O-linkedHMM predict
880Phosphothreonine(PKC)HMM predict
886O-linkedHMM predict
886O-linkedHMM predict
896Phosphothreonine(PKC)HMM predict
917Phosphotyrosine(INSR)HMM predict
917Phosphotyrosine(Abl)HMM predict
917Phosphotyrosine(Syk)HMM predict
960O-linkedHMM predict
964O-linkedHMM predict
965PhosphothreonineHMM predict
1001Phosphoserine(ATM)HMM predict
1017Phosphoserine(ATM)HMM predict
1027O-linkedHMM predict
1051O-linkedHMM predict
1052O-linkedHMM predict
1055Phosphothreonine(MAPK)HMM predict
1061Phosphothreonine(MAPK)HMM predict
1073Phosphotyrosine(INSR)HMM predict
1076Phosphoserine(CAMK2)HMM predict
1131Phosphoserine(PKG)HMM predict
1133O-linkedHMM predict
1133Phosphoserine(CDC2)HMM predict
1133Phosphoserine(ATM)HMM predict
1133PhosphoserineHMM predict
1140Phosphotyrosine(SRC)HMM predict
1140Phosphotyrosine(Syk)HMM predict
1142Phosphothreonine(PKC)HMM predict
1145O-linkedHMM predict
1145Phosphoserine(CK1)HMM predict
1147O-linkedHMM predict
1153O-linkedHMM predict
1155Phosphoserine(CDC2)HMM predict
1155Phosphoserine(ATM)HMM predict
1208O-linkedHMM predict
1256O-linkedHMM predict
1261O-linkedHMM predict
1283O-linkedHMM predict
1284O-linkedHMM predict
1284Phosphoserine(CDC2)HMM predict
1284Phosphoserine(IKK)HMM predict
1291O-linkedHMM predict
1291O-linkedHMM predict
1295Phosphothreonine(PKC)HMM predict
1308O-linkedHMM predict
1308Phosphoserine(IKK)HMM predict
1309O-linkedHMM predict
1309Phosphothreonine(CDK)HMM predict
1332N-linkedHMM predict
1351Phosphoserine(CK2)HMM predict
1351PhosphoserineHMM predict
1358Phosphoserine(CK2)HMM predict
1386Phosphoserine(CK2)HMM predict
1398N-linkedHMM predict
1403O-linkedHMM predict
1442N-linkedHMM predict
1446Phosphoserine(CK2)HMM predict
1447Phosphoserine(IKK)HMM predict
1449Phosphoserine(CK1)HMM predict
1449Phosphoserine(ATM)HMM predict
1468N-linkedHMM predict
1494Phosphoserine(ATM)HMM predict
1523Phosphothreonine(PKC)HMM predict
1548Phosphoserine(CK1)HMM predict
1581O-linkedHMM predict
1583O-linkedHMM predict
1585O-linkedHMM predict
1594Phosphotyrosine(INSR)HMM predict
1596Phosphoserine(CK2)HMM predict
1614Phosphoserine(CK1)HMM predict
1631Phosphoserine(CK2)HMM predict
1635Phosphoserine(IKK)HMM predict
1642Phosphoserine(CK2)HMM predict
1663N-linkedHMM predict
1664Phosphothreonine(PKA)HMM predict
1664Phosphothreonine(CK2)HMM predict
1690SulfotyrosineHMM predict
1697O-linkedHMM predict
1743Phosphoserine(CDK)HMM predict
1763O-linkedHMM predict
1764O-linkedHMM predict
1775Phosphoserine(IKK)HMM predict
1823Phosphothreonine(PKC)HMM predict
1827Phosphoserine(CDC2)HMM predict
1847O-linkedHMM predict
1848O-linkedHMM predict
1853O-linkedHMM predict
1877O-linkedHMM predict
1879O-linkedHMM predict
1898N-linkedHMM predict
1917Phosphotyrosine(EGFR)HMM predict
1917Phosphotyrosine(INSR)HMM predict
1943Phosphothreonine(PKC)HMM predict
1967O-linkedHMM predict
1970O-linkedHMM predict
1970Phosphoserine(CDC2)HMM predict
1970Phosphoserine(CDK)HMM predict
1972O-linkedHMM predict
1990O-linkedHMM predict
1991O-linkedHMM predict
1992O-linkedHMM predict
2006Phosphoserine(CK2)HMM predict
2017O-linkedHMM predict
2017Phosphothreonine(PKC)HMM predict
2034O-linkedHMM predict
2081Phosphoserine(PKG)HMM predict
2112Phosphoserine(CK1)HMM predict
2112Phosphoserine(CK2)HMM predict
2115Phosphothreonine(CK2)HMM predict
2116Phosphoserine(CK1)HMM predict
2128Phosphoserine(CDC2)HMM predict
2146Phosphothreonine(CK2)HMM predict
2162MethyllysineHMM predict
2176Phosphoserine(IKK)HMM predict
2179N-linkedHMM predict
2225Phosphoserine(CDC2)HMM predict
2272N-linkedHMM predict
2280N-linkedHMM predict
2281N-linkedHMM predict
2288O-linkedHMM predict
2295Phosphoserine(CK1)HMM predict
2316Phosphoserine(ATM)HMM predict
2326O-linkedHMM predict
2326Phosphoserine(IKK)HMM predict
2328O-linkedHMM predict
2329O-linkedHMM predict
2330O-linkedHMM predict
2345O-linkedHMM predict
2360N-linkedHMM predict
2371Phosphothreonine(PKC)HMM predict
2382O-linkedHMM predict
2385N-linkedHMM predict
2392N-linkedHMM predict
2395O-linkedHMM predict
2399O-linkedHMM predict
2425Phosphotyrosine(Syk)HMM predict
2455Phosphoserine(PKG)HMM predict
2478O-linkedHMM predict
2496N-linkedHMM predict
2499O-linkedHMM predict
2499Phosphoserine(CDC2)HMM predict
2503O-linkedHMM predict
2504Phosphoserine(IKK)HMM predict
2505O-linkedHMM predict
2509O-linkedHMM predict
2608PhosphoserineHMM predict
2612Phosphoserine(CK2)HMM predict
2623Phosphotyrosine(EGFR)HMM predict
2656Phosphothreonine(PKC)HMM predict
2657Phosphotyrosine(Syk)HMM predict
2726Phosphoserine(CK1)HMM predict
2751Phosphotyrosine(Syk)HMM predict
2751SulfotyrosineHMM predict
2779Phosphotyrosine(Syk)HMM predict
2806PhosphotyrosineHMM predict
2810O-linkedHMM predict
2811O-linkedHMM predict
2821Phosphoserine(PKG)HMM predict
2822Phosphoserine(ATM)HMM predict
2824Phosphothreonine(CDC2)HMM predict
2826Phosphoserine(IKK)HMM predict
2827Phosphoserine(CDC2)HMM predict
2838Phosphoserine(CK2)HMM predict
2856O-linkedHMM predict
2864Phosphoserine(CK2)HMM predict
2883Phosphotyrosine(Jak)HMM predict
2883Phosphotyrosine(Syk)HMM predict
2891O-linkedHMM predict
2893Phosphoserine(CDC2)HMM predict
2893Phosphoserine(CDK)HMM predict
2934N-linkedHMM predict
2953Phosphothreonine(CDK)HMM predict
2977O-linkedHMM predict
2979Phosphoserine(IKK)HMM predict
3003O-linkedHMM predict
3003O-linkedHMM predict
3003Phosphothreonine(PKC)HMM predict
3007Phosphoserine(CDC2)HMM predict
3007Phosphoserine(ATM)HMM predict
3067N-linkedHMM predict
3153S-palmitoylHMM predict
3171SulfotyrosineHMM predict
3189Phosphothreonine(PKA)HMM predict
3209Phosphoserine(CK2)HMM predict
3247SulfotyrosineHMM predict
3293Phosphothreonine(PKA)HMM predict
3354N-linkedHMM predict
3358Phosphotyrosine(EGFR)HMM predict
3363Phosphoserine(PKA)HMM predict
3369N-linkedHMM predict
3377Phosphoserine(IKK)HMM predict
3379N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004385
  • Location:chr5 82803338-82912736
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
P300 T0-glioblastomaGSE21026 82915176 82916981 1805 3342
P300 T30-glioblastomaGSE21026 82915196 82915824 628 2774
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF JurkatGSE12889 82805232 82805433 201 0
CTCF G2GSE9613 82804160 82804330 170 0
CTCF G2GSE9613 82804644 82806339 1695 0
CTCF G2GSE9613 82895782 82896105 323 0
ER MCF7GSE19013 82804458 82805014 556 0
FOXA1 MCF7GSE15244 82894552 82895718 1166 0
Fos K562GSE19551 82847400 82847820 420 0
FoxA1 MCF7MACSdata 82839047 82839204 157 0
FoxA1 MCF7MACSdata 82895202 82895495 293 0
H3K27me3 colorectalcancer 82802180 82805738 3558 0
Myc K562GSE19551 82847628 82847800 172 0
NRSF JurkatGSE13047 82870337 82870654 317 0
NRSF JurkatSISSRdata 82870425 82870654 229 0
NRSF-mono JurkatQuESTdata 82870356 82870653 297 0
NRSF-poly JurkatQuESTdata 82870337 82870729 392 0
Nanog hESGSE18292 82807464 82808277 813 0
Nanog hESGSE18292 82895672 82896043 371 0
Oct1 H2O2-HelaGSE14283 82895139 82895168 29 0
Oct1 HelaGSE14283 82807758 82807791 33 0
Oct1 HelaGSE14283 82895135 82895168 33 0
Oct1 HelaGSE14283 82896621 82896688 67 0
P300 T0-glioblastomaGSE21026 82899104 82900217 1113 0
P300 T30-glioblastomaGSE21026 82899428 82900382 954 0
Pol3 K562GSE19551 82847515 82847833 318 0
RARA MCF7GSE15244 82894442 82895846 1404 0
Rb QuiescentGSE19898 82804274 82804533 259 0
TFAP2C MCF7GSE21234 82841153 82841494 341 0
hScc1 BcellGSE12603 82804644 82805888 1244 0
hScc1 BcellGSE12603 82817754 82817935 181 0
hScc1 BcellGSE12603 82895652 82896028 376 0
hScc1 CdLSGSE12603 82804884 82805626 742 0
hScc1 CdLSGSE12603 82895548 82896028 480 0
hScc1 G2GSE9613 82804742 82806395 1653 0
hScc1 G2GSE9613 82895476 82896139 663 0
p130 shRbQuiescentGSE19898 82804733 82805082 349 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-138 hsa-mir-138-2 16 19004786
hsa-miR-138 hsa-mir-138-1 3 19004786
hsa-miR-143 hsa-mir-143 5 20489207
hsa-miR-143* hsa-mir-143 5 20489207
hsa-miR-21 hsa-mir-21 17 21063030
hsa-miR-21* hsa-mir-21 17 21063030
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
21192 mRNA CSPG2 chr5 82803338 82912737 430 EST chr5 82872916 82912895Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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