AutismKB 2.0

Annotation Detail for ADRA1B


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Basic Information Top
Gene Symbol:ADRA1B ( ADRA1,ALPHA1BAR )
Gene Full Name: adrenergic, alpha-1B-, receptor
Band: 5q33.3
Quick LinksEntrez ID:147; OMIM: 104220; Uniprot ID:ADA1B_HUMAN; ENSEMBL ID: ENSG00000170214; HGNC ID: 278
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
10N-linked (GlcNAc...) (Potential).
24N-linked (GlcNAc...) (Potential).
29N-linked (GlcNAc...) (Potential).
34N-linked (GlcNAc...) (Potential).
264Phosphothreonine (By similarity).
267Phosphoserine (By similarity).
Location(AA) Modifications Resource
10N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
24N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
29N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
34N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
264Phosphothreonine (By similarity).Swiss-Prot 53.0
267Phosphoserine (By similarity).Swiss-Prot 53.0
365S-palmitoyl cysteine (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
10N-linkedHMM predict
24N-linkedHMM predict
29N-linkedHMM predict
32O-linkedHMM predict
34N-linkedHMM predict
233Phosphothreonine(PKC)HMM predict
266Phosphoserine(CK1)HMM predict
365S-palmitoylHMM predict
396Phosphoserine(PKC)HMM predict
396Phosphoserine(PKA)HMM predict
400Phosphoserine(ATM)HMM predict
406Phosphoserine(CAMK2)HMM predict
406Phosphoserine(IKK)HMM predict
423O-linkedHMM predict
425O-linkedHMM predict
425Phosphoserine(CDC2)HMM predict
425Phosphoserine(CDK)HMM predict
427Phosphoserine(MAPK)HMM predict
433MethylarginineHMM predict
465MethylarginineHMM predict
484Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000679
  • Location:chr5 159276317-159332596
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF JurkatGSE12889 159275963 159276113 150 280
P300 T30-glioblastomaGSE21026 159264841 159265585 744 11105
RARA MCF7GSE15244 159272449 159273426 977 3380
Rb GrowingGSE19898 159264858 159265012 154 11383
TFAP2C MCF7GSE21234 159272509 159273024 515 3551
hScc1 BcellGSE12603 159275582 159276316 734 369
hScc1 CdLSGSE12603 159275517 159276401 884 359
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 159347031 159347248 217 14543
CTCF CD4SISSRdata 159347031 159347248 217 14543
CTCF HelaGSE12889 159347025 159347238 213 14535
CTCF JurkatGSE12889 159346996 159347261 265 14532
CTCF G2GSE9613 159332729 159333178 449 357
CTCF G2GSE9613 159335079 159335535 456 2711
CTCF G2GSE9613 159336910 159337104 194 4411
P300 T30-glioblastomaGSE21026 159334431 159335857 1426 2548
P300 T30-glioblastomaGSE21026 159341005 159342034 1029 8923
hScc1 BcellGSE12603 159332591 159333073 482 236
hScc1 BcellGSE12603 159346403 159347465 1062 14338
hScc1 CdLSGSE12603 159346875 159347465 590 14574
p130 shRbQuiescentGSE19898 159334458 159335079 621 2172
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 159275845 159276790 945 0
CTCF G2GSE9613 159299311 159299723 412 0
CTCF G2GSE9613 159310230 159310648 418 0
CTCF G2GSE9613 159331663 159332051 388 0
hScc1 BcellGSE12603 159331699 159331949 250 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
21762 mRNA ADRA1B chr5 159276317 159332129 1106 mRNA chr5 159296204 159297310 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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