AutismKB 2.0

Annotation Detail for TMC4


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Basic Information Top
Gene Symbol:TMC4 ( MGC39329 )
Gene Full Name: transmembrane channel-like 4
Band: 19q13.42
Quick LinksEntrez ID:147798; OMIM: NA; Uniprot ID:TMC4_HUMAN; ENSEMBL ID: ENSG00000167608; HGNC ID: 22998
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
107N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
101N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
76O-linkedHMM predict
129Phosphothreonine(CK2)HMM predict
198O-linkedHMM predict
199Phosphoserine(IKK)HMM predict
227Phosphotyrosine(INSR)HMM predict
452Phosphoserine(CK2)HMM predict
507S-palmitoylHMM predict
570Phosphoserine(MAPK)HMM predict
575Phosphothreonine(PKC)HMM predict
579Phosphoserine(PKG)HMM predict
632Phosphoserine(CK1)HMM predict
632O-linkedHMM predict
684Phosphothreonine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_144686
  • Location:chr19 59355658-59368663
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
LIN9 SGSE7516 59354921 59356378 1457 9
p130 SenescentGSE19898 59355130 59356075 945 56
p130 shRbQuiescentGSE19898 59355062 59356241 1179 7
p130 G0GSE7516 59355166 59356118 952 17
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 59364037 59364313 276 0
CTCF CD4SISSRdata 59364037 59364313 276 0
CTCF HelaGSE12889 59363996 59364316 320 0
CTCF JurkatGSE12889 59364051 59364349 298 0
CTCF G2GSE9613 59363839 59364284 445 0
CTCF G2GSE9613 59367054 59367486 432 0
E2F4 G0GSE7516 59355239 59356079 840 0
LIN9 G0GSE7516 59355130 59356822 1692 0
Myc K562GSE19551 59363988 59364324 336 0
Oct1 H2O2-HelaGSE14283 59367208 59367243 35 0
Oct1 HelaGSE14283 59367078 59367117 39 0
Oct1 HelaGSE14283 59367210 59367240 30 0
TFAP2C MCF7GSE21234 59367849 59368929 1080 0
hScc1 BcellGSE12603 59359836 59360479 643 0
p130 QuiescentGSE19898 59355439 59356021 582 0
p130 shRbSenescentGSE19898 59355430 59356333 903 0
p130 SGSE7516 59355239 59356079 840 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018