AutismKB 2.0

Annotation Detail for ADRA1A


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Basic Information Top
Gene Symbol:ADRA1A ( ADRA1C,ADRA1L1,ALPHA1AAR )
Gene Full Name: adrenergic, alpha-1A-, receptor
Band: 8p21.2
Quick LinksEntrez ID:148; OMIM: 104221; Uniprot ID:ADA1A_HUMAN; ENSEMBL ID: ENSG00000120907; HGNC ID: 277
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
7N-linked (GlcNAc...) (Potential).
13N-linked (GlcNAc...) (Potential).
22N-linked (GlcNAc...) (Potential).
215Phosphoserine; by PKA (Potential).
Location(AA) Modifications Resource
7N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
13N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
22N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
215Phosphoserine (by PKA) (Potential).Swiss-Prot 53.0
345S-palmitoyl cysteine (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
7N-linkedHMM predict
12Phosphoserine(IKK)HMM predict
13N-linkedHMM predict
15O-linkedHMM predict
24O-linkedHMM predict
125Phosphotyrosine(Jak)HMM predict
184Phosphotyrosine(INSR)HMM predict
184Phosphotyrosine(EGFR)HMM predict
239MethyllysineHMM predict
347S-palmitoylHMM predict
351Phosphoserine(PKG)HMM predict
417Phosphoserine(IKK)HMM predict
434S-palmitoylHMM predict
435S-palmitoylHMM predict
440Phosphothreonine(MAPK)HMM predict
440Phosphothreonine(CDK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000680
  • Location:chr8 26683138-26778838
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 26778014 26780986 2972 662
Oct1 HelaGSE14283 26782261 26782308 47 3446
Oct1 HelaGSE14283 26793566 26793625 59 14757
Rb GrowingGSE19898 26780676 26780815 139 1907
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 26767869 26768207 338 0
CTCF G2GSE9613 26777720 26778502 782 0
Nanog hESGSE18292 26737940 26738464 524 0
Nanog hESGSE18292 26776962 26777485 523 0
Oct1 HelaGSE14283 26703748 26703776 28 0
Oct1 HelaGSE14283 26706827 26706855 28 0
Oct1 HelaGSE14283 26724863 26724891 28 0
Oct1 HelaGSE14283 26725075 26725115 40 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018