AutismKB 2.0

Annotation Detail for DIRAS1


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Basic Information Top
Gene Symbol:DIRAS1 ( Di-Ras1,FLJ42681,GBTS1,RIG )
Gene Full Name: DIRAS family, GTP-binding RAS-like 1
Band: 19p13.3
Quick LinksEntrez ID:148252; OMIM: 607862; Uniprot ID:DIRA1_HUMAN; ENSEMBL ID: ENSG00000176490; HGNC ID: 19127
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
44Effector region (Potential).
195Cysteine methyl ester (Potential).
Location(AA) Modifications Resource
195S-geranylgeranyl cysteine (Bysimilarity).Swiss-Prot 53.0
Location(AA) Modification Resource
8Phosphotyrosine(Jak)HMM predict
44Phosphotyrosine(EGFR)HMM predict
93Phosphoserine(PKG)HMM predict
188Phosphothreonine(PKA)HMM predict
195CysteineHMM predict
195S-farnesylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_145173
  • Location:chr19 2665564-2672363
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 2673854 2674638 784 1883
P300 T30-glioblastomaGSE21026 2673687 2674519 832 1740
Rb SenescentGSE19898 2674096 2674405 309 1887
p130 SenescentGSE19898 2674399 2674656 257 2164
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 2662531 2662887 356 2856
Rb GrowingGSE19898 2662620 2662781 161 2864
p130 QuiescentGSE19898 2662171 2662340 169 3309
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 2665498 2665875 377 0
NRSF JurkatGSE13047 2672042 2672240 198 0
NRSF-mono JurkatQuESTdata 2671917 2672252 335 0
NRSF-poly JurkatQuESTdata 2672012 2672224 212 0
hScc1 BcellGSE12603 2668527 2668903 376 0
Validated miRNA targets Top
Cis-Nats regulation Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018