AutismKB 2.0

Annotation Detail for SIK1


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Basic Information Top
Gene Symbol:SIK1 ( MSK,SIK,SNF1LK )
Gene Full Name: salt-inducible kinase 1
Band: 21q22.3
Quick LinksEntrez ID:150094; OMIM: 605705; Uniprot ID:SIK1_HUMAN; ENSEMBL ID: ENSG00000142178; HGNC ID: 11142
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
182Phosphothreonine.
186Phosphoserine (By similarity).
435Phosphoserine.
460Phosphothreonine.
479Phosphothreonine.
575Phosphoserine.
578Phosphoserine (By similarity).
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_173354
  • Location:chr21 43658828-43671429
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 43672424 43673096 672 1331
FOXA1 MCF7GSE15244 43674268 43676103 1835 3756
PHF8 293TGSE20725 43670969 43672498 1529 304
RARA MCF7GSE15244 43672533 43672868 335 1271
RARA MCF7GSE15244 43674374 43675915 1541 3715
RARG MCF7GSE15244 43673209 43675991 2782 3171
Rb SenescentGSE19898 43671553 43671709 156 202
TFAP2C MCF7GSE21234 43672280 43672902 622 1162
TFAP2C MCF7GSE21234 43674083 43674911 828 3068
hScc1 BcellGSE12603 43671559 43672501 942 601
hScc1 BcellGSE12603 43676781 43677231 450 5577
hScc1 CdLSGSE12603 43671559 43671910 351 305
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 43649088 43649469 381 9550
ER MCF7GSE19013 43641800 43643145 1345 16356
ER MCF7GSE19013 43653638 43654315 677 4852
NFkBII GM10847GSE19485 43653768 43655649 1881 4120
NFkBII GM18526GSE19485 43642727 43644726 1999 15102
RARA MCF7GSE15244 43653986 43654314 328 4679
RARG MCF7GSE15244 43653986 43654314 328 4679
Rb GrowingGSE19898 43654496 43654708 212 4227
Rb QuiescentGSE19898 43645554 43645725 171 13189
TFAP2C MCF7GSE21234 43640740 43641856 1116 17531
TFAP2C MCF7GSE21234 43656305 43657152 847 2100
hScc1 BcellGSE12603 43641149 43641406 257 17551
hScc1 BcellGSE12603 43642589 43643447 858 15811
hScc1 BcellGSE12603 43643694 43644251 557 14856
hScc1 BcellGSE12603 43644630 43645242 612 13893
hScc1 BcellGSE12603 43647408 43648506 1098 10872
hScc1 BcellGSE12603 43654813 43655465 652 3690
hScc1 BcellGSE12603 43656212 43657028 816 2209
p130 shRbSenescentGSE19898 43645550 43645698 148 13205
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 43663682 43664159 477 0
CTCF G2GSE9613 43664660 43665331 671 0
H3K4me3 colorectalcancer 43668970 43670073 1103 0
H3ac HepG2E 43668312 43669460 1148 0
H3ac HepG2E 43669789 43670324 535 0
Myc hESGSE17917 43660185 43660480 295 0
Pol2 GM12878GSE19551 43671277 43671547 270 0
PolII HeLaGSE12783 43654410 43675482 21072 0
TAF HelaGSE8489 43666958 43667289 331 0
TAF HelaGSE8489 43667727 43667960 233 0
TAF HelaGSE8489 43668312 43670284 1972 0
TAF k562GSE8489 43668312 43668642 330 0
hScc1 BcellGSE12603 43661479 43661788 309 0
hScc1 BcellGSE12603 43664624 43665030 406 0
hScc1 BcellGSE12603 43665969 43666224 255 0
hScc1 BcellGSE12603 43670201 43671194 993 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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