AutismKB 2.0

Annotation Detail for CTSB


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Basic Information Top
Gene Symbol:CTSB ( APPS,CPSB )
Gene Full Name: cathepsin B
Band: 8p23.1
Quick LinksEntrez ID:1508; OMIM: 116810; Uniprot ID:CATB_HUMAN; ENSEMBL ID: ENSG00000164733; HGNC ID: 2527
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
192N-linked (GlcNAc...).
Location(AA) Modifications Resource
192N-linked (GlcNAc...).Swiss-Prot 53.0
Location(AA) Modification Resource
10S-palmitoylHMM predict
38N-linkedHMM predict
48Phosphotyrosine(Syk)HMM predict
104Phosphoserine(IKK)HMM predict
173Phosphotyrosine(INSR)HMM predict
173Phosphotyrosine(Abl)HMM predict
192N-linkedHMM predict
235Phosphoserine(CK2)HMM predict
289N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001908
  • Location:chr8 11737444-11763054
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 11774655 11774953 298 11750
FOXA1 DLD1GSE12801 11771886 11772249 363 9013
FOXA1 MCF7GSE15244 11763712 11763857 145 730
Gata1 K562GSE18868 11774216 11775168 952 11638
Gata2 K562GSE18868 11774184 11775105 921 11590
H3ac HepG2E 11763580 11763857 277 664
H3ac HepG2E 11779382 11779768 386 16521
P300 T30-glioblastomaGSE21026 11771580 11773435 1855 9453
PHF8 Hs68minusFBSGSE20725 11762301 11763868 1567 30
USF1 HepG2E 11763544 11763857 313 646
USF2 HepG2E 11763580 11763857 277 664
hScc1 CdLSGSE12603 11772030 11772249 219 9085
p130 SenescentGSE19898 11772647 11772953 306 9746
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 11740292 11740556 264 0
CTCF G2GSE9613 11742824 11744369 1545 0
CTCF G2GSE9613 11748210 11748796 586 0
CTCF G2GSE9613 11757155 11757790 635 0
CTCF G2GSE9613 11762430 11763273 843 0
FOXA1 MCF7GSE15244 11747920 11748832 912 0
Fos K562GSE19551 11748690 11749346 656 0
Gata2 K562GSE18868 11757131 11758161 1030 0
H3K4me2 HCT116GSE10453 11760980 11761260 280 0
H3ac HepG2E 11760980 11761980 1000 0
Oct1 H2O2-HelaGSE14283 11756131 11756159 28 0
P300 T30-glioblastomaGSE21026 11748558 11749622 1064 0
PHF8 HeLaGSE20725 11762370 11763357 987 0
Pol2 GM12878GSE19551 11741258 11742160 902 0
Pol2 GM12878GSE19551 11762717 11763114 397 0
RARA MCF7GSE15244 11748531 11749383 852 0
RARA MCF7GSE15244 11757155 11757675 520 0
RARG MCF7GSE15244 11748174 11749383 1209 0
RARG MCF7GSE15244 11757155 11757675 520 0
TFAP2C MCF7GSE21234 11743125 11743764 639 0
TFAP2C MCF7GSE21234 11756989 11757903 914 0
USF1 HepG2E 11747449 11748391 942 0
USF1 HepG2E 11760980 11761509 529 0
hScc1 BcellGSE12603 11762042 11763368 1326 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018