AutismKB 2.0

Annotation Detail for ADRA2B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ADRA2B ( ADRA2L1,ADRA2RL1,ADRARL1,ALPHA2BAR )
Gene Full Name: adrenergic, alpha-2B-, receptor
Band: 2q11.2
Quick LinksEntrez ID:151; OMIM: 104260; Uniprot ID:ADA2B_HUMAN; ENSEMBL ID: ENSG00000222040; HGNC ID: 282
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
1AcetylmethionineHMM predict
12O-linkedHMM predict
125Phosphothreonine(CDC2)HMM predict
159MethylarginineHMM predict
261Phosphothreonine(MAPK)HMM predict
318O-linkedHMM predict
318Phosphoserine(CDK)HMM predict
318Phosphoserine(IKK)HMM predict
318Phosphoserine(CDC2)HMM predict
324Phosphoserine(MAPK)HMM predict
364Phosphothreonine(PKC)HMM predict
418N-linkedHMM predict
422N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000682
  • Location:chr2 96142352-96145614
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 96145116 96148805 3689 1346
TFAP2C MCF7GSE21234 96147919 96148843 924 2767
hScc1 BcellGSE12603 96145458 96145830 372 30
hScc1 BcellGSE12603 96146218 96146861 643 925
hScc1 G2GSE9613 96145727 96146973 1246 736
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 96128028 96128937 909 13870
CTCF G2GSE9613 96129694 96129933 239 12539
CTCF G2GSE9613 96133967 96134347 380 8196
CTCF G2GSE9613 96138577 96139098 521 3515
CTCF G2GSE9613 96139455 96139906 451 2672
CTCF G2GSE9613 96140285 96140644 359 1888
CTCF G2GSE9613 96141187 96143135 1948 192
Myc K562GSE19551 96124714 96125015 301 17488
Oct1 HelaGSE14283 96135237 96135266 29 7101
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 96144011 96144804 793 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018