AutismKB 2.0

Annotation Detail for SPICE1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SPICE1 ( CCDC52,FLJ26064,FLJ44949,SPICE )
Gene Full Name: spindle and centriole associated protein 1
Band: 3q13.2
Quick LinksEntrez ID:152185; OMIM: 613447; Uniprot ID:SPICE_HUMAN; ENSEMBL ID: ENSG00000163611; HGNC ID: 25083
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
235Phosphothreonine.
644Phosphoserine.
760Phosphoserine.
764Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_144718
  • Location:chr3 114644258-114716692
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 114717597 114717776 179 994
H3ac HepG2E 114717597 114717888 291 1050
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 114695604 114695826 222 0
CTCF G2GSE9613 114696538 114696922 384 0
CTCF G2GSE9613 114716497 114716850 353 0
FOXA1 MCF7GSE15244 114715582 114716850 1268 0
H3K4me2 HCT116GSE10453 114715656 114716457 801 0
H3K4me3 colorectalcancer 114714985 114716497 1512 0
H3ac HepG2E 114714985 114716646 1661 0
LIN9 G0GSE7516 114715941 114716829 888 0
Oct1 HelaGSE14283 114707650 114707725 75 0
PHF8 293TGSE20725 114716010 114717334 1324 0
PHF8 HeLaGSE20725 114715839 114717421 1582 0
RARA MCF7GSE15244 114715481 114716850 1369 0
RARG MCF7GSE15244 114715582 114716850 1268 0
Rb QuiescentGSE19898 114716288 114716756 468 0
Rb SenescentGSE19898 114716256 114716815 559 0
TAF k562GSE8489 114716083 114716421 338 0
hScc1 BcellGSE12603 114716154 114716850 696 0
hScc1 CdLSGSE12603 114695569 114695826 257 0
hScc1 CdLSGSE12603 114696430 114696956 526 0
p130 QuiescentGSE19898 114716225 114716811 586 0
p130 SenescentGSE19898 114716323 114716808 485 0
p130 shRbQuiescentGSE19898 114716023 114716561 538 0
p130 shRbSenescentGSE19898 114716186 114716758 572 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018