AutismKB 2.0

Annotation Detail for FGD5


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Basic Information Top
Gene Symbol:FGD5 ( ZFYVE23 )
Gene Full Name: FYVE, RhoGEF and PH domain containing 5
Band: 3p25.1
Quick LinksEntrez ID:152273; OMIM: NA; Uniprot ID:FGD5_HUMAN; ENSEMBL ID: ENSG00000154783; HGNC ID: 19117
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
632Phosphoserine (By similarity).
635Phosphoserine (By similarity).
Location(AA) Modifications Resource
632Phosphoserine (By similarity).Swiss-Prot 53.0
635Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
28N-linkedHMM predict
32N-linkedHMM predict
59Phosphoserine(CK2)HMM predict
65Phosphotyrosine(Syk)HMM predict
91Phosphoserine(MAPK)HMM predict
94Phosphoserine(CK2)HMM predict
95Phosphoserine(CK1)HMM predict
95Phosphoserine(CK2)HMM predict
161PhosphoserineHMM predict
163Phosphoserine(CK2)HMM predict
163Phosphoserine(CK1)HMM predict
163Phosphoserine(CK2)HMM predict
177Phosphoserine(CK1)HMM predict
181Phosphoserine(CK1)HMM predict
181Phosphoserine(ATM)HMM predict
209Phosphothreonine(MAPK)HMM predict
239Phosphothreonine(PKA)HMM predict
294Phosphoserine(ATM)HMM predict
356Phosphoserine(IKK)HMM predict
356O-linkedHMM predict
359O-linkedHMM predict
363Phosphoserine(MAPK)HMM predict
363Phosphoserine(ATM)HMM predict
366Phosphoserine(CK2)HMM predict
478Phosphothreonine(PKC)HMM predict
486O-linkedHMM predict
563Phosphotyrosine(Syk)HMM predict
596Phosphoserine(ATM)HMM predict
603O-linkedHMM predict
607O-linkedHMM predict
607Phosphoserine(IKK)HMM predict
608Phosphothreonine(MAPK)HMM predict
608Phosphothreonine(CDC2)HMM predict
674N-linkedHMM predict
681Phosphoserine(CK1)HMM predict
682Phosphoserine(CK1)HMM predict
684Phosphoserine(CK1)HMM predict
685Phosphoserine(CK1)HMM predict
699Phosphoserine(CK1)HMM predict
701Phosphoserine(PKG)HMM predict
701Phosphoserine(IKK)HMM predict
701Phosphoserine(PKC)HMM predict
703Phosphoserine(CDC2)HMM predict
703Phosphoserine(CDK)HMM predict
716Phosphoserine(CK2)HMM predict
718Phosphoserine(IKK)HMM predict
740Phosphoserine(IKK)HMM predict
765PhosphoserineHMM predict
765Phosphoserine(PKB)HMM predict
774Phosphotyrosine(INSR)HMM predict
774Phosphotyrosine(Syk)HMM predict
784Phosphotyrosine(Syk)HMM predict
784Phosphotyrosine(INSR)HMM predict
812Phosphoserine(PKG)HMM predict
820Phosphotyrosine(EGFR)HMM predict
820Phosphotyrosine(Jak)HMM predict
820Phosphotyrosine(INSR)HMM predict
820SulfotyrosineHMM predict
820Phosphotyrosine(Syk)HMM predict
820PhosphotyrosineHMM predict
844Phosphotyrosine(INSR)HMM predict
844Phosphotyrosine(Syk)HMM predict
844Phosphotyrosine(EGFR)HMM predict
848Phosphotyrosine(Syk)HMM predict
863Phosphothreonine(CK2)HMM predict
864Phosphoserine(CK1)HMM predict
864Phosphoserine(CK2)HMM predict
864PhosphoserineHMM predict
870PhosphoserineHMM predict
870Phosphoserine(CK2)HMM predict
870Phosphoserine(CK1)HMM predict
871Phosphoserine(CK1)HMM predict
871Phosphoserine(CK2)HMM predict
876Phosphoserine(CK1)HMM predict
902Phosphoserine(CK1)HMM predict
907Phosphotyrosine(INSR)HMM predict
907Phosphotyrosine(SRC)HMM predict
1011Phosphoserine(MAPK)HMM predict
1031Phosphothreonine(PKC)HMM predict
1064Phosphotyrosine(INSR)HMM predict
1064Phosphotyrosine(Syk)HMM predict
1165Phosphoserine(PKG)HMM predict
1210Phosphotyrosine(Syk)HMM predict
1238Phosphothreonine(PKC)HMM predict
1274N-linkedHMM predict
1278N-linkedHMM predict
1319Phosphoserine(IKK)HMM predict
1324Phosphoserine(CDC2)HMM predict
1338Phosphoserine(IKK)HMM predict
1340N-linkedHMM predict
1360Phosphoserine(CK2)HMM predict
1398Phosphoserine(CAMK2)HMM predict
1422Phosphoserine(CK1)HMM predict
1456MethionineHMM predict
1459AlanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_152536
  • Location:chr3 14835809-14950898
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 14818278 14818524 246 17409
CTCF G2GSE9613 14820168 14820341 173 15555
CTCF G2GSE9613 14821017 14821900 883 14351
CTCF G2GSE9613 14826961 14827471 510 8594
H3K27me3 colorectalcancer 14828310 14829147 837 7081
NFkBII GM12892GSE19485 14817726 14818893 1167 17500
hScc1 BcellGSE12603 14821168 14821832 664 14310
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 14955583 14955955 372 4871
hScc1 BcellGSE12603 14952939 14953308 369 2225
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 14898782 14904711 5929 0
CTCF CD4GSE12889 14932452 14932656 204 0
CTCF CD4GSE12889 14937613 14938059 446 0
CTCF CD4SISSRdata 14932452 14932656 204 0
CTCF CD4SISSRdata 14937613 14938059 446 0
CTCF JurkatGSE12889 14937602 14938032 430 0
CTCF G2GSE9613 14835640 14836910 1270 0
CTCF G2GSE9613 14849946 14850248 302 0
CTCF G2GSE9613 14851549 14851701 152 0
CTCF G2GSE9613 14858661 14858848 187 0
CTCF G2GSE9613 14878155 14878731 576 0
CTCF G2GSE9613 14880114 14880433 319 0
CTCF G2GSE9613 14881332 14881909 577 0
CTCF G2GSE9613 14886601 14887181 580 0
CTCF G2GSE9613 14891272 14892566 1294 0
CTCF G2GSE9613 14904188 14904364 176 0
CTCF G2GSE9613 14918828 14919050 222 0
CTCF G2GSE9613 14919318 14919559 241 0
CTCF G2GSE9613 14923877 14924232 355 0
CTCF G2GSE9613 14928172 14928516 344 0
CTCF G2GSE9613 14929849 14930324 475 0
CTCF G2GSE9613 14932279 14932853 574 0
CTCF G2GSE9613 14934770 14934994 224 0
CTCF G2GSE9613 14937201 14938777 1576 0
CTCF G2GSE9613 14942071 14942709 638 0
ER E2-MCF7GSE14664 14841942 14841991 49 0
ER MCF7GSE19013 14852479 14852900 421 0
FOXA1 MCF7GSE15244 14838651 14839745 1094 0
FOXA1 MCF7GSE15244 14893780 14894563 783 0
FOXA1 MCF7GSE15244 14916159 14917014 855 0
FOXA1 MCF7GSE15244 14917991 14918478 487 0
FoxA1 MCF7MACSdata 14839404 14839641 237 0
Myc K562GSE19551 14937560 14938030 470 0
Nanog hESGSE18292 14880523 14880697 174 0
Oct1 H2O2-HelaGSE14283 14841959 14842004 45 0
Oct1 HelaGSE14283 14841960 14842004 44 0
RARA MCF7GSE15244 14838651 14839745 1094 0
RARA MCF7GSE15244 14877518 14879128 1610 0
RARA MCF7GSE15244 14893265 14894693 1428 0
RARA MCF7GSE15244 14895553 14896464 911 0
RARA MCF7GSE15244 14900187 14901050 863 0
RARA MCF7GSE15244 14917991 14918478 487 0
RARG MCF7GSE15244 14893713 14894634 921 0
RARG MCF7GSE15244 14917991 14918478 487 0
STAT1 IFNSISSRdata 14864158 14865130 972 0
Sox2 hESGSE18292 14942226 14942548 322 0
TFAP2C MCF7GSE21234 14839356 14839939 583 0
TFAP2C MCF7GSE21234 14893181 14894463 1282 0
TFAP2C MCF7GSE21234 14900531 14902250 1719 0
TFAP2C MCF7GSE21234 14934839 14935448 609 0
TFAP2C MCF7GSE21234 14937371 14938002 631 0
TFAP2C MCF7GSE21234 14950450 14950940 490 0
hScc1 BcellGSE12603 14880245 14880695 450 0
hScc1 BcellGSE12603 14937201 14938032 831 0
hScc1 BcellGSE12603 14942071 14942709 638 0
hScc1 CdLSGSE12603 14937468 14938331 863 0
hScc1 CdLSGSE12603 14942071 14942676 605 0
hScc1 G2GSE9613 14932279 14932816 537 0
hScc1 G2GSE9613 14937468 14938526 1058 0
hScc1 G2GSE9613 14942071 14942709 638 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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