AutismKB 2.0

Annotation Detail for KLB


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Basic Information Top
Gene Symbol:KLB ( BKL,MGC142213 )
Gene Full Name: klotho beta
Band: 4p14
Quick LinksEntrez ID:152831; OMIM: 611135; Uniprot ID:KLOTB_HUMAN; ENSEMBL ID: ENSG00000134962; HGNC ID: 15527
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
71N-linked (GlcNAc...) (Potential).
120N-linked (GlcNAc...) (Potential).
125N-linked (GlcNAc...) (Potential).
211N-linked (GlcNAc...) (Potential).
308N-linked (GlcNAc...) (Potential).
391N-linked (GlcNAc...) (Potential).
554N-linked (GlcNAc...) (Potential).
611N-linked (GlcNAc...) (Potential).
702N-linked (GlcNAc...) (Potential).
706N-linked (GlcNAc...) (Potential).
971N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
71N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
120N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
125N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
211N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
308N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
391N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
554N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
611N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
702N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
706N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
971N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
29Phosphothreonine(PKA)HMM predict
66N-linkedHMM predict
71N-linkedHMM predict
120N-linkedHMM predict
125N-linkedHMM predict
131SulfotyrosineHMM predict
211N-linkedHMM predict
252Phosphothreonine(PKC)HMM predict
260O-linkedHMM predict
340SulfotyrosineHMM predict
538Phosphoserine(CK2)HMM predict
538Phosphoserine(IKK)HMM predict
542O-linkedHMM predict
542Phosphoserine(CDC2)HMM predict
554N-linkedHMM predict
558N-linkedHMM predict
702N-linkedHMM predict
706N-linkedHMM predict
709Phosphotyrosine(SRC)HMM predict
843Phosphoserine(CK2)HMM predict
858Phosphoserine(CDK)HMM predict
858Phosphoserine(CDC2)HMM predict
880Phosphotyrosine(INSR)HMM predict
886Phosphotyrosine(INSR)HMM predict
971N-linkedHMM predict
973O-linkedHMM predict
977PhosphoserineHMM predict
977Phosphoserine(ATM)HMM predict
1002S-palmitoylHMM predict
1003S-palmitoylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_175737
  • Location:chr4 39084867-39126747
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 39082487 39082694 207 2277
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 39124785 39125749 964 0
H3ac HepG2E 39084790 39085584 794 0
H3ac HepG2E 39088102 39089024 922 0
Sox2 hESGSE18292 39113986 39114231 245 0
TFAP2C MCF7GSE21234 39124554 39125326 772 0
TFAP2C MCF7GSE21234 39125359 39125628 269 0
hScc1 BcellGSE12603 39124117 39125317 1200 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
19586 mRNA LOC152831 chr4 39231038 39272919 257 mRNA chr4 39267158 39271113Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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