AutismKB 2.0

Annotation Detail for ADRBK1


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Basic Information Top
Gene Symbol:ADRBK1 ( BARK1,BETA-ARK1,FLJ16718,GRK2 )
Gene Full Name: adrenergic, beta, receptor kinase 1
Band: 11q13.1
Quick LinksEntrez ID:156; OMIM: 109635; Uniprot ID:ARBK1_HUMAN; ENSEMBL ID: ENSG00000173020; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
350Phosphoserine.
353Phosphothreonine.
670Phosphoserine.
Location(AA) Modifications Resource
29Phosphoserine (PKC alpha)Phospho.ELM 6.0
670Phosphoserine (MAPK
685Phosphoserine (PKA
Location(AA) Modification Resource
23Phosphothreonine(PKA)HMM predict
86Phosphotyrosine(Syk)HMM predict
97Phosphothreonine(PKC)HMM predict
284Phosphoserine(ATM)HMM predict
356PhosphotyrosineHMM predict
356Phosphotyrosine(Syk)HMM predict
356Phosphotyrosine(INSR)HMM predict
506PhosphotyrosineHMM predict
553SulfotyrosineHMM predict
599Phosphoserine(IKK)HMM predict
608Phosphoserine(CK2)HMM predict
608Phosphoserine(CK1)HMM predict
670Phosphoserine(MAPK)HMM predict
670Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001619
  • Location:chr11 66790668-66810932
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 66786724 66787132 408 3741
CTCF CD4GSE12889 66790180 66790466 286 346
CTCF CD4SISSRdata 66786724 66787132 408 3741
CTCF CD4SISSRdata 66790180 66790466 286 346
CTCF HelaGSE12889 66786745 66787014 269 3789
FOXA1 MCF7GSE15244 66786181 66787666 1485 3745
H3ac HepG2E 66788392 66790052 1660 1447
RARA MCF7GSE15244 66786731 66787196 465 3705
USF1 HepG2E 66786030 66786841 811 4233
hScc1 BcellGSE12603 66786424 66787127 703 3893
hScc1 BcellGSE12603 66790086 66790416 330 418
hScc1 CdLSGSE12603 66786619 66787492 873 3613
hScc1 CdLSGSE12603 66789757 66790416 659 582
hScc1 G2GSE9613 66790122 66790416 294 400
p130 shRbSenescentGSE19898 66790216 66790443 227 339
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 66811278 66812413 1135 913
VDR GM10861-stimGSE22484 66810267 66813615 3348 1009
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 66800225 66802746 2521 0
ER E2-MCF7GSE14664 66807547 66807584 37 0
ER MCF7GSE19013 66797275 66797741 466 0
ETS1 JurkatGSE17954 66801198 66802694 1496 0
FOXA1 DLD1GSE12801 66791465 66792078 613 0
FOXA1 MCF7GSE15244 66791432 66792012 580 0
NRSF pAbJurkat 66790923 66792048 1125 0
NRSF pAbJurkat 66799324 66799908 584 0
Oct1 H2O2-HelaGSE14283 66795160 66795208 48 0
Oct1 HelaGSE14283 66795181 66795209 28 0
RARG MCF7GSE15244 66795249 66795697 448 0
Rb GrowingGSE19898 66797214 66797478 264 0
Rb SenescentGSE19898 66801582 66801823 241 0
TFAP2C MCF7GSE21234 66795541 66796285 744 0
TFAP2C MCF7GSE21234 66799668 66800457 789 0
hScc1 BcellGSE12603 66790735 66791296 561 0
hScc1 BcellGSE12603 66804136 66804290 154 0
hScc1 BcellGSE12603 66810417 66811161 744 0
p130 QuiescentGSE19898 66801908 66802093 185 0
p130 SenescentGSE19898 66800221 66800401 180 0
p130 shRbQuiescentGSE19898 66801053 66801986 933 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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