AutismKB 2.0

Annotation Detail for ADRBK2


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Basic Information Top
Gene Symbol:ADRBK2 ( BARK2,GRK3 )
Gene Full Name: adrenergic, beta, receptor kinase 2
Band: 22q11|22q12.1
Quick LinksEntrez ID:157; OMIM: 109636; Uniprot ID:ARBK2_HUMAN; ENSEMBL ID: ENSG00000100077; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
23Phosphothreonine(PKA)HMM predict
29O-linkedHMM predict
92Phosphotyrosine(Syk)HMM predict
137Phosphoserine(CK1)HMM predict
284Phosphoserine(ATM)HMM predict
356PhosphotyrosineHMM predict
356Phosphotyrosine(Syk)HMM predict
356Phosphotyrosine(INSR)HMM predict
368Phosphotyrosine(INSR)HMM predict
444Phosphoserine(ATM)HMM predict
506Phosphotyrosine(Syk)HMM predict
526Phosphotyrosine(SRC)HMM predict
553SulfotyrosineHMM predict
608Phosphoserine(CK2)HMM predict
608Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005160
  • Location:chr22 24290945-24449913
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 24289624 24290490 866 889
H3K27me3 colorectalcancer 24287329 24288144 815 3209
H3K27me3 colorectalcancer 24288946 24290234 1288 1356
H3K4me3 colorectalcancer 24289550 24289950 400 1196
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 24428068 24428240 172 0
CTCF CD4SISSRdata 24428068 24428240 172 0
ER Breast-CancerGSE22609 24445176 24445546 370 0
NRSF mAbJurkat 24377691 24377911 220 0
Oct4 hESGSE21916 24346087 24346762 675 0
hScc1 BcellGSE12603 24290662 24291726 1064 0
hScc1 CdLSGSE12603 24290444 24291537 1093 0
hScc1 CdLSGSE12603 24292932 24293638 706 0
p63 keratinocytesGSE17611 24428390 24429353 963 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018