AutismKB 2.0

Annotation Detail for CYP11B1


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Basic Information Top
Gene Symbol:CYP11B1 ( CPN1,CYP11B,DKFZp686B05283,FHI,FLJ36771,P450C11 )
Gene Full Name: cytochrome P450, family 11, subfamily B, polypeptide 1
Band: 8q24.3
Quick LinksEntrez ID:1584; OMIM: 610613; Uniprot ID:C11B1_HUMAN; ENSEMBL ID: ENSG00000160882; HGNC ID: 2591
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
61Phosphotyrosine(EGFR)HMM predict
61Phosphotyrosine(Syk)HMM predict
169Phosphoserine(ATM)HMM predict
360O-linkedHMM predict
439Phosphotyrosine(Syk)HMM predict
448MethylarginineHMM predict
450S-palmitoylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000497
  • Location:chr8 143950776-143958237
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 143943351 143943681 330 7261
CTCF CD4SISSRdata 143943351 143943681 330 7261
CTCF HelaGSE12889 143943378 143943598 220 7289
TFAP2C MCF7GSE21234 143943887 143944556 669 6555
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF JurkatGSE13047 143951973 143953434 1461 0
NRSF mAbJurkat 143951514 143953433 1919 0
NRSF-mono JurkatQuESTdata 143952340 143953484 1144 0
NRSF pAbJurkat 143951853 143953292 1439 0
NRSF pAbJurkat 143953817 143954606 789 0
NRSF-poly JurkatQuESTdata 143952082 143953613 1531 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
26049 EST chr8 143912664 143994934 7462 mRNA CYP11B1 chr8 143950776 143958238 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018