AutismKB 2.0

Annotation Detail for PRUNE2


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Basic Information Top
Gene Symbol:PRUNE2 ( A214N16.3,BMCC1,BNIPXL,C9orf65,DKFZp762K117,FLJ50060,FLJ54876,FLJ59118,KIAA0367,RP11-58J3.2,bA214N16.3 )
Gene Full Name: prune homolog 2 (Drosophila)
Band: 9q21.2
Quick LinksEntrez ID:158471; OMIM: 610691; Uniprot ID:PRUN2_HUMAN; ENSEMBL ID: ENSG00000106772; HGNC ID: 25209
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
111DHH motif (By similarity).
576Phosphoserine.
586Phosphoserine.
595Phosphoserine.
597Phosphoserine.
699Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
34O-linkedHMM predict
143Phosphoserine(CK2)HMM predict
178Phosphothreonine(PKC)HMM predict
193Phosphoserine(CK1)HMM predict
236Phosphoserine(CK1)HMM predict
236Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015225
  • Location:chr9 78416112-78518457
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
KLF4 hESGSE17917 78522349 78522644 295 4039
Myc K562GSE19551 78522979 78523193 214 4629
Oct1 HelaGSE14283 78538219 78538255 36 19780
hScc1 BcellGSE12603 78520778 78520987 209 2425
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Myc K562GSE19551 78414659 78415057 398 1255
p130 QuiescentGSE19898 78405698 78405846 148 10341
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 78463422 78463723 301 0
CTCF CD4GSE12889 78509401 78509621 220 0
CTCF CD4SISSRdata 78463422 78463723 301 0
CTCF CD4SISSRdata 78509401 78509621 220 0
FOXA1 MCF7GSE15244 78463112 78463573 461 0
LIN54 G0GSE7516 78497894 78498138 244 0
Myc K562GSE19551 78451072 78451330 258 0
Myc hESGSE17917 78496476 78496871 395 0
Nanog ESGSE20650 78495275 78495721 446 0
PAX3-FKHR Rh4GSE19063 78505888 78507237 1349 0
STAT1 HeLaGSE12783 78509095 78510066 971 0
STAT1 IFNSISSRdata 78509148 78509761 613 0
TFAP2C MCF7GSE21234 78447504 78448063 559 0
hScc1 BcellGSE12603 78463112 78463573 461 0
hScc1 BcellGSE12603 78509277 78509807 530 0
hScc1 CdLSGSE12603 78463112 78463573 461 0
hScc1 CdLSGSE12603 78509277 78509842 565 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018