Annotation Detail for ADSS
Basic Information Top
| Gene Symbol: | ADSS ( ADEH,MGC20404 ) |
|---|---|
| Gene Full Name: | adenylosuccinate synthase |
| Band: | 1q44 |
| Quick Links | Entrez ID:159; OMIM: 103060; Uniprot ID:PURA2_HUMAN; ENSEMBL ID: ENSG00000035687; HGNC ID: 292 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 2 | N-acetylalanine. | |
| Location(AA) | Modifications | Resource |
|---|
| Location(AA) | Modification | Resource |
|---|---|---|
| 22 | Methylarginine | HMM predict |
| 90 | N-linked | HMM predict |
| 223 | Phosphotyrosine(INSR) | HMM predict |
| 270 | O-linked | HMM predict |
| 272 | Phosphoserine(IKK) | HMM predict |
| 273 | N-linked | HMM predict |
| 275 | O-linked | HMM predict |
| 332 | Phosphothreonine(PKC) | HMM predict |
| 428 | Phosphotyrosine(EGFR) | HMM predict |
- RefSeq ID: NM_001126
- Location:chr1 242638419-242682035
- strand:-
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| E2F4 | G0 | GSE7516 | 242681929 | 242682448 | 519 | 153 |
| ETS1 | Jurkat | GSE17954 | 242681608 | 242682776 | 1168 | 157 |
| LIN9 | G0 | GSE7516 | 242681929 | 242682448 | 519 | 153 |
| Rb | Quiescent | GSE19898 | 242682132 | 242682263 | 131 | 162 |
| Rb | Senescent | GSE19898 | 242681750 | 242682361 | 611 | 20 |
| p130 | Quiescent | GSE19898 | 242681918 | 242682397 | 479 | 122 |
| p130 | Senescent | GSE19898 | 242681890 | 242682403 | 513 | 111 |
| p130 | shRbSenescent | GSE19898 | 242681721 | 242682388 | 667 | 19 |
| p130 | G0 | GSE7516 | 242681965 | 242682448 | 483 | 171 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 242681144 | 242682060 | 916 | 0 |
| H3K4me3 | colorectal | cancer | 242679913 | 242681593 | 1680 | 0 |
| H3ac | HepG2 | E | 242680380 | 242681248 | 868 | 0 |
| PHF8 | HeLa | GSE20725 | 242680703 | 242682134 | 1431 | 0 |
| Rb | Quiescent | GSE19898 | 242681841 | 242682104 | 263 | 0 |
| TAF | k562 | GSE8489 | 242678996 | 242679879 | 883 | 0 |
| TAF | k562 | GSE8489 | 242680344 | 242680983 | 639 | 0 |
| hScc1 | Bcell | GSE12603 | 242681018 | 242682198 | 1180 | 0 |
| hScc1 | CdLS | GSE12603 | 242681144 | 242682448 | 1304 | 0 |
| hScc1 | G2 | GSE9613 | 242680983 | 242682060 | 1077 | 0 |
| p130 | shRbQuiescent | GSE19898 | 242681806 | 242682264 | 458 | 0 |
| p63 | keratinocytes | GSE17611 | 242674736 | 242675357 | 621 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-let-7b | hsa-let-7b | 22 | 18668040 |
| hsa-let-7b* | hsa-let-7b | 22 | 18668040 |
| hsa-miR-1 | hsa-mir-1-2 | 18 | 18668040 |
| hsa-miR-1 | hsa-mir-1-1 | 20 | 18668040 |
| hsa-miR-155 | hsa-mir-155 | 21 | 18668040 |
| hsa-miR-155* | hsa-mir-155 | 21 | 18668040 |
| hsa-miR-16 | hsa-mir-16-1 | 13 | 18668040 |
| hsa-miR-16 | hsa-mir-16-2 | 3 | 18668040 |
| hsa-miR-30a | hsa-mir-30a | 6 | 18668040 |
| hsa-miR-30a* | hsa-mir-30a | 6 | 18668040 |
| hsa-miR-30b | hsa-mir-30b | 8 | 18668040 |
| hsa-miR-30b* | hsa-mir-30b | 8 | 18668040 |
| hsa-miR-30c | hsa-mir-30c-2 | 6 | 18668040 |
| hsa-miR-30c | hsa-mir-30c-1 | 1 | 18668040 |
| hsa-miR-30c-1* | hsa-mir-30c-1 | 1 | 18668040 |
| hsa-miR-30c-2* | hsa-mir-30c-2 | 6 | 18668040 |
| hsa-miR-30d | hsa-mir-30d | 8 | 18668040 |
| hsa-miR-30d* | hsa-mir-30d | 8 | 18668040 |
| hsa-miR-30e | hsa-mir-30e | 1 | 18668040 |
| hsa-miR-30e* | hsa-mir-30e | 1 | 18668040 |
| ID in Tarbase | Data Type | Support Type | miRNA | Gene | Direct Support | Publication |
|---|---|---|---|---|---|---|
| 1026 | Unknown | pSILAC | miR-16 | ADSS | down 75-50% | 18668040 |
| Ensembl | Protein Type | Differentially expressed in | Pathology or Event | Mis Regulation | Gene Expression | Tumour Involvement |
| ENSG00000035687 | n_a | n_a | n_a | n_a | n_a |
Cis-Nats regulation