AutismKB 2.0

Annotation Detail for DAB1


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Basic Information Top
Gene Symbol:DAB1 ( - )
Gene Full Name: disabled homolog 1 (Drosophila)
Band: 1p32.2
Quick LinksEntrez ID:1600; OMIM: 603448; Uniprot ID:DAB1_HUMAN; ENSEMBL ID: ENSG00000173406; HGNC ID: 2661
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
198Phosphotyrosine (By similarity).
220Phosphotyrosine (By similarity).
524Phosphoserine; by CDK5 (By similarity).
Location(AA) Modifications Resource
198Phosphotyrosine (By similarity).Swiss-Prot 53.0
198PhosphotyrosinePhospho.ELM 6.0
220Phosphotyrosine (By similarity).Swiss-Prot 53.0
220PhosphotyrosinePhospho.ELM 6.0
232PhosphotyrosinePhospho.ELM 6.0
491Phosphoserine (by CDK5) (By similarity).Swiss-Prot 53.0
491Phosphoserine (CDK
515Phosphoserine (CDK
Location(AA) Modification Resource
13Phosphothreonine(PKC)HMM predict
128Phosphotyrosine(Jak)HMM predict
198Phosphotyrosine(SRC)HMM predict
220Phosphotyrosine(INSR)HMM predict
220Phosphotyrosine(EGFR)HMM predict
220Phosphotyrosine(SRC)HMM predict
220Phosphotyrosine(Syk)HMM predict
220PhosphotyrosineHMM predict
225Phosphoserine(ATM)HMM predict
232Phosphotyrosine(SRC)HMM predict
237Phosphoserine(ATM)HMM predict
241Phosphoserine(IKK)HMM predict
259O-linkedHMM predict
260Phosphoserine(CDK)HMM predict
260O-linkedHMM predict
263O-linkedHMM predict
266Phosphothreonine(MAPK)HMM predict
276Phosphoserine(ATM)HMM predict
278Phosphothreonine(PKC)HMM predict
298O-linkedHMM predict
385Phosphothreonine(MAPK)HMM predict
393O-linkedHMM predict
397O-linkedHMM predict
399Phosphoserine(CK1)HMM predict
400Phosphoserine(CDC2)HMM predict
428O-linkedHMM predict
439O-linkedHMM predict
440O-linkedHMM predict
468N-linkedHMM predict
473O-linkedHMM predict
474O-linkedHMM predict
474O-linkedHMM predict
476O-linkedHMM predict
476Phosphothreonine(CDK)HMM predict
476Phosphothreonine(MAPK)HMM predict
478O-linkedHMM predict
478Phosphoserine(IKK)HMM predict
478O-linkedHMM predict
481O-linkedHMM predict
481Phosphoserine(CDC2)HMM predict
481Phosphoserine(IKK)HMM predict
481Phosphoserine(CDK)HMM predict
484O-linkedHMM predict
484Phosphothreonine(MAPK)HMM predict
484Phosphothreonine(CDC2)HMM predict
484O-linkedHMM predict
490O-linkedHMM predict
491PhosphoserineHMM predict
491Phosphoserine(PKB)HMM predict
491Phosphoserine(CDC2)HMM predict
491Phosphoserine(IKK)HMM predict
491Phosphoserine(CDK)HMM predict
493Phosphoserine(CK1)HMM predict
493O-linkedHMM predict
498O-linkedHMM predict
498Phosphoserine(CK2)HMM predict
515Phosphoserine(CDC2)HMM predict
515Phosphoserine(CDK)HMM predict
519Phosphoserine(CK1)HMM predict
528Phosphoserine(ATM)HMM predict
532Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_021080
  • Location:chr1 57236166-58488798
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog hESGSE18292 57232259 57232666 407 3704
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 57727517 57728524 1007 0
CTCF CD4GSE12889 58285621 58285813 192 0
CTCF CD4GSE12889 58401369 58401489 120 0
CTCF CD4SISSRdata 58285621 58285813 192 0
CTCF CD4SISSRdata 58401369 58401489 120 0
CTCF JurkatGSE12889 58285496 58285945 449 0
CTCF G2GSE9613 57255859 57256108 249 0
CTCF G2GSE9613 57660541 57661260 719 0
CTCF G2GSE9613 57776829 57777195 366 0
CTCF G2GSE9613 57858918 57859144 226 0
CTCF G2GSE9613 58298189 58298401 212 0
CTCF G2GSE9613 58309038 58309230 192 0
CTCF G2GSE9613 58396937 58397275 338 0
CTCF G2GSE9613 58401610 58401957 347 0
CTCF G2GSE9613 58487978 58488359 381 0
ER E2-MCF7GSE14664 57414752 57414788 36 0
ER E2-MCF7GSE14664 58113076 58113132 56 0
ER E2-MCF7GSE14664 58251967 58252007 40 0
ER E2-MCF7GSE14664 58420659 58420703 44 0
ER E2-MCF7GSE14664 58424993 58425025 32 0
ER E2-MCF7GSE14664 58451467 58451501 34 0
ER Fulvestrant-MCF7GSE14664 57414752 57414785 33 0
ER Fulvestrant-MCF7GSE14664 58414677 58414711 34 0
Fos K562GSE19551 58412814 58413362 548 0
FoxA1 MCF7MACSdata 57518485 57518691 206 0
FoxA1 MCF7MACSdata 58421504 58421907 403 0
Gata1 K562GSE18868 57456800 57457403 603 0
Gata2 K562GSE18868 57456788 57457435 647 0
H3K27me3 colorectalcancer 58486481 58488091 1610 0
H3ac HepG2E 58005899 58006099 200 0
H3ac HepG2E 58294346 58294820 474 0
KLF4 hESGSE17917 57741256 57741505 249 0
Myc K562GSE19551 57467433 57467645 212 0
Myc K562GSE19551 58285548 58285889 341 0
NFkBII GM12892GSE19485 57442088 57443159 1071 0
NRSF JurkatGSE13047 57575804 57576097 293 0
NRSF JurkatGSE13047 58205127 58205829 702 0
NRSF JurkatGSE13047 58447751 58448320 569 0
NRSF JurkatGSE13047 58483083 58483898 815 0
NRSF mAbJurkat 57909831 57910155 324 0
NRSF mAbJurkat 58202803 58204384 1581 0
NRSF mAbJurkat 58205009 58205892 883 0
NRSF mAbJurkat 58206311 58206805 494 0
NRSF mAbJurkat 58443020 58444043 1023 0
NRSF mAbJurkat 58445539 58445935 396 0
NRSF mAbJurkat 58447139 58451414 4275 0
NRSF mAbJurkat 58481160 58482825 1665 0
NRSF mAbJurkat 58483164 58484793 1629 0
NRSF mAbJurkat 58485198 58485878 680 0
NRSF mAbJurkat 58486275 58486807 532 0
NRSF mAbJurkat 58487075 58487400 325 0
NRSF-mono JurkatQuESTdata 57497167 57497520 353 0
NRSF-mono JurkatQuESTdata 57910045 57910401 356 0
NRSF-mono JurkatQuESTdata 58204860 58205839 979 0
NRSF-mono JurkatQuESTdata 58447750 58448278 528 0
NRSF-mono JurkatQuESTdata 58448524 58448733 209 0
NRSF-mono JurkatQuESTdata 58483079 58483604 525 0
NRSF-poly JurkatQuESTdata 57497092 57497524 432 0
NRSF-poly JurkatQuESTdata 57910036 57910420 384 0
NRSF-poly JurkatQuESTdata 58205221 58205795 574 0
NRSF-poly JurkatQuESTdata 58483078 58483787 709 0
Nanog ESGSE20650 57286966 57287449 483 0
Nanog ESGSE20650 57350469 57350860 391 0
Nanog ESGSE20650 57689173 57689662 489 0
Nanog ESGSE20650 58407278 58407976 698 0
Nanog hESGSE18292 57287096 57287382 286 0
Nanog hESGSE18292 57404079 57404638 559 0
Nanog hESGSE18292 58070818 58071087 269 0
Oct1 H2O2-HelaGSE14283 57359755 57359790 35 0
Oct1 H2O2-HelaGSE14283 57458475 57458521 46 0
Oct1 H2O2-HelaGSE14283 57552763 57552791 28 0
Oct1 H2O2-HelaGSE14283 57578606 57578642 36 0
Oct1 H2O2-HelaGSE14283 57721582 57721616 34 0
Oct1 H2O2-HelaGSE14283 57880398 57880430 32 0
Oct1 H2O2-HelaGSE14283 57950920 57950947 27 0
Oct1 H2O2-HelaGSE14283 58163330 58163369 39 0
Oct1 H2O2-HelaGSE14283 58180772 58180803 31 0
Oct1 H2O2-HelaGSE14283 58216872 58216903 31 0
Oct1 H2O2-HelaGSE14283 58325418 58325448 30 0
Oct1 H2O2-HelaGSE14283 58415980 58416012 32 0
Oct1 H2O2-HelaGSE14283 58441461 58441488 27 0
Oct1 HelaGSE14283 57304973 57305009 36 0
Oct1 HelaGSE14283 57356694 57356727 33 0
Oct1 HelaGSE14283 57359755 57359799 44 0
Oct1 HelaGSE14283 57367441 57367473 32 0
Oct1 HelaGSE14283 57419476 57419509 33 0
Oct1 HelaGSE14283 57458478 57458521 43 0
Oct1 HelaGSE14283 57522508 57522553 45 0
Oct1 HelaGSE14283 57541227 57541257 30 0
Oct1 HelaGSE14283 57578606 57578641 35 0
Oct1 HelaGSE14283 57701380 57701432 52 0
Oct1 HelaGSE14283 57721586 57721616 30 0
Oct1 HelaGSE14283 57869906 57869984 78 0
Oct1 HelaGSE14283 57880399 57880432 33 0
Oct1 HelaGSE14283 58051314 58051371 57 0
Oct1 HelaGSE14283 58163330 58163381 51 0
Oct1 HelaGSE14283 58204347 58204379 32 0
Oct1 HelaGSE14283 58205791 58205832 41 0
Oct1 HelaGSE14283 58216875 58216905 30 0
Oct1 HelaGSE14283 58325418 58325448 30 0
Oct1 HelaGSE14283 58415980 58416012 32 0
Oct1 HelaGSE14283 58420649 58420690 41 0
Oct1 HelaGSE14283 58420881 58420919 38 0
Oct1 HelaGSE14283 58424980 58425024 44 0
Oct4 hESGSE17917 58244950 58245481 531 0
Oct4 hESGSE21916 58244710 58245406 696 0
Oct4 hESGSE21916 58269517 58270233 716 0
Oct4 hESGSE21916 58270249 58270762 513 0
P300 T30-glioblastomaGSE21026 57727272 57728618 1346 0
RNAII Tamoxifen-MCF7GSE14664 57880394 57880435 41 0
Rb QuiescentGSE19898 57461348 57461507 159 0
Rb shRbQuiescentGSE19898 57835294 57835561 267 0
STAT1 HeLaGSE12782 57724190 57725241 1051 0
STAT1 HeLaGSE12783 57724250 57725207 957 0
STAT1 HeLaGSE12783 57755754 57758171 2417 0
TFAP2C MCF7GSE21234 58062740 58063150 410 0
TFAP2C MCF7GSE21234 58459569 58459977 408 0
USF1 HepG2E 57751622 57751794 172 0
hScc1 BcellGSE12603 57613223 57613443 220 0
hScc1 BcellGSE12603 57660578 57660784 206 0
hScc1 BcellGSE12603 57662235 57662966 731 0
hScc1 BcellGSE12603 58099208 58099423 215 0
hScc1 BcellGSE12603 58174965 58175214 249 0
hScc1 BcellGSE12603 58299108 58299396 288 0
hScc1 BcellGSE12603 58487978 58488359 381 0
hScc1 G2GSE9613 57756476 57756768 292 0
p130 QuiescentGSE19898 57591875 57592051 176 0
p63 keratinocytesGSE17611 57487717 57488376 659 0
p63 keratinocytesGSE17611 57949285 57950143 858 0
p63 keratinocytesGSE17611 58083003 58084039 1036 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
854 mRNA chr1 57169043 57192210 16492 mRNA DAB1 chr1 57175718 57468759 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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