AutismKB 2.0

Annotation Detail for DAB2


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Basic Information Top
Gene Symbol:DAB2 ( DOC-2,DOC2,FLJ26626 )
Gene Full Name: disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
Band: 5p13.1
Quick LinksEntrez ID:1601; OMIM: 601236; Uniprot ID:DAB2_HUMAN; ENSEMBL ID: ENSG00000153071; HGNC ID: 2662
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
151Phosphothreonine.
170Phosphotyrosine.
221Phosphothreonine.
227Phosphoserine.
342Phosphotyrosine.
393Phosphoserine.
394Phosphoserine.
401Phosphoserine.
729Phosphoserine (By similarity).
Location(AA) Modifications Resource
24Phosphoserine (PKC alpha;PK)Phospho.ELM 6.0
221Phosphothreonine.Swiss-Prot 53.0
221PhosphothreoninePhospho.ELM 6.0
227Phosphoserine.Swiss-Prot 53.0
227PhosphoserinePhospho.ELM 6.0
342Phosphotyrosine.Swiss-Prot 53.0
393Phosphoserine.Swiss-Prot 53.0
394Phosphoserine.Swiss-Prot 53.0
401PhosphoserinePhospho.ELM 6.0
401Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
24Phosphoserine(PKC)HMM predict
69Phosphoserine(IKK)HMM predict
69Phosphoserine(ATM)HMM predict
85Phosphoserine(ATM)HMM predict
96N-linkedHMM predict
227Phosphoserine(IKK)HMM predict
307Phosphothreonine(MAPK)HMM predict
310Phosphoserine(IKK)HMM predict
313Phosphoserine(IKK)HMM predict
316Phosphoserine(CDC2)HMM predict
323N-linkedHMM predict
324Phosphoserine(CK1)HMM predict
324Phosphoserine(CK2)HMM predict
325O-linkedHMM predict
325Phosphoserine(CK1)HMM predict
326Phosphoserine(CK1)HMM predict
327O-linkedHMM predict
328Phosphoserine(CK1)HMM predict
329Phosphothreonine(CDK)HMM predict
329O-linkedHMM predict
329Phosphothreonine(MAPK)HMM predict
352N-linkedHMM predict
367O-linkedHMM predict
367O-linkedHMM predict
368O-linkedHMM predict
368Phosphoserine(CDK)HMM predict
371O-linkedHMM predict
371Phosphothreonine(PKC)HMM predict
390Phosphoserine(ATM)HMM predict
401Phosphoserine(CDC2)HMM predict
418Phosphoserine(CK1)HMM predict
423Phosphoserine(IKK)HMM predict
441MethylarginineHMM predict
445Phosphothreonine(PKC)HMM predict
467Phosphoserine(CK2)HMM predict
467O-linkedHMM predict
471Phosphoserine(CAMK2)HMM predict
471Phosphoserine(CDC2)HMM predict
471Phosphoserine(IKK)HMM predict
471Phosphoserine(CDK)HMM predict
471O-linkedHMM predict
541Phosphoserine(ATM)HMM predict
564O-linkedHMM predict
565O-linkedHMM predict
565O-linkedHMM predict
565Phosphothreonine(MAPK)HMM predict
585Phosphoserine(IKK)HMM predict
586Phosphothreonine(PKC)HMM predict
588Phosphoserine(CDC2)HMM predict
605O-linkedHMM predict
610Phosphoserine(IKK)HMM predict
618Phosphothreonine(CDK)HMM predict
625MethylarginineHMM predict
676Phosphoserine(IKK)HMM predict
678O-linkedHMM predict
745Phosphoserine(CDK)HMM predict
749Phosphoserine(IKK)HMM predict
749O-linkedHMM predict
749Phosphoserine(CAMK2)HMM predict
753Phosphoserine(ATM)HMM predict
761Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001343
  • Location:chr5 39408502-39460702
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 39460264 39461286 1022 73
p130 SenescentGSE19898 39460525 39461450 925 285
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 39405849 39408940 3091 1108
FoxA1 MCF7MACSdata 39406489 39406696 207 1910
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 39434992 39436132 1140 0
CTCF CD4GSE12889 39412238 39412431 193 0
CTCF CD4SISSRdata 39412238 39412431 193 0
CTCF G2GSE9613 39411783 39413235 1452 0
Fos K562GSE19551 39435172 39435963 791 0
H3ac HepG2E 39458493 39460741 2248 0
Myc K562GSE19551 39412111 39412476 365 0
NRSF mAbJurkat 39436405 39436543 138 0
Nanog hESGSE18292 39412217 39412608 391 0
Nanog hESGSE18292 39449040 39449472 432 0
P300 T30-glioblastomaGSE21026 39434399 39436166 1767 0
P300 T30-glioblastomaGSE21026 39446668 39447576 908 0
STAT1 HeLaGSE12783 39433548 39436247 2699 0
STAT1 IFNSISSRdata 39434706 39436209 1503 0
Sox2 hESGSE18292 39412118 39412609 491 0
TAF HelaGSE8489 39459466 39460471 1005 0
hScc1 BcellGSE12603 39411815 39412645 830 0
hScc1 CdLSGSE12603 39412030 39412713 683 0
hScc1 G2GSE9613 39411783 39413307 1524 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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