AutismKB 2.0

Annotation Detail for AP2A2


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Basic Information Top
Gene Symbol:AP2A2 ( ADTAB,CLAPA2,HIP9,HYPJ )
Gene Full Name: adaptor-related protein complex 2, alpha 2 subunit
Band: 11p15.5
Quick LinksEntrez ID:161; OMIM: 607242; Uniprot ID:AP2A2_HUMAN; ENSEMBL ID: ENSG00000183020; HGNC ID: 562
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
35N6-acetyllysine.
808Phosphotyrosine (By similarity).
Location(AA) Modifications Resource
Location(AA) Modification Resource
124N-linkedHMM predict
179Phosphoserine(MAPK)HMM predict
209O-linkedHMM predict
238Phosphothreonine(PKC)HMM predict
250Phosphotyrosine(Syk)HMM predict
302Phosphoserine(IKK)HMM predict
361Phosphoserine(CK1)HMM predict
378Phosphothreonine(PKC)HMM predict
383Phosphoserine(CAMK2)HMM predict
418Phosphoserine(CK2)HMM predict
438SulfotyrosineHMM predict
455Phosphotyrosine(Jak)HMM predict
501Phosphotyrosine(INSR)HMM predict
517Phosphoserine(CDC2)HMM predict
610Phosphoserine(CK1)HMM predict
648Phosphoserine(IKK)HMM predict
648O-linkedHMM predict
649O-linkedHMM predict
650O-linkedHMM predict
650Phosphoserine(IKK)HMM predict
653O-linkedHMM predict
654Phosphothreonine(MAPK)HMM predict
654O-linkedHMM predict
654Phosphothreonine(CDK)HMM predict
654O-linkedHMM predict
656Phosphoserine(CDC2)HMM predict
656Phosphoserine(MAPK)HMM predict
677O-linkedHMM predict
678O-linkedHMM predict
689Phosphoserine(CK1)HMM predict
693Phosphoserine(IKK)HMM predict
744N-linkedHMM predict
752N-linkedHMM predict
928Phosphoserine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_012305
  • Location:chr11 915840-1002238
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 915587 915881 294 107
CTCF CD4SISSRdata 915587 915881 294 107
CTCF JurkatGSE12889 915575 915799 224 154
ETS1 JurkatGSE17954 909015 909527 512 6570
H3ac HepG2E 913788 914725 937 1584
Myc K562GSE19551 909072 909620 548 6495
Myc hESGSE17917 915647 915899 252 68
NFkBII GM10847GSE19485 915128 916507 1379 23
USF1 HepG2E 909382 909565 183 6367
VDR GM10861-UnstimGSE22484 915232 916288 1056 81
hScc1 BcellGSE12603 915154 916071 917 228
hScc1 CdLSGSE12603 915559 916071 512 26
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF-mono JurkatQuESTdata 1015079 1015548 469 13075
NRSF pAbJurkat 1004237 1005101 864 2431
NRSF pAbJurkat 1005782 1007669 1887 4487
NRSF pAbJurkat 1008020 1008698 678 6121
NRSF pAbJurkat 1009135 1009565 430 7112
NRSF pAbJurkat 1009962 1010397 435 7941
NRSF pAbJurkat 1011848 1012730 882 10051
NRSF pAbJurkat 1013505 1014574 1069 11801
NRSF pAbJurkat 1018882 1020165 1283 17285
NRSF pAbJurkat 1021197 1021709 512 19215
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ERG prostate-cancerGSE14092 954465 955087 622 0
FOXA1 MCF7GSE15244 933580 934210 630 0
FOXA1 MCF7GSE15244 954343 955094 751 0
H3ac HepG2E 916381 916897 516 0
H3ac HepG2E 923296 923819 523 0
H3ac HepG2E 930780 931025 245 0
H3ac HepG2E 933580 935317 1737 0
H3ac HepG2E 942908 943117 209 0
KLF4 hESGSE17917 923906 924305 399 0
Myc K562GSE19551 970730 970999 269 0
NRSF pAbJurkat 951107 951422 315 0
NRSF pAbJurkat 954749 955411 662 0
NRSF pAbJurkat 968687 969074 387 0
NRSF pAbJurkat 975294 976057 763 0
NRSF pAbJurkat 981821 983228 1407 0
NRSF pAbJurkat 984412 984958 546 0
Nanog hESGSE18292 924487 924899 412 0
Nanog hESGSE18292 934840 935220 380 0
Oct4 ESGSE20650 954732 954995 263 0
Oct4 hESGSE17917 934682 935258 576 0
Oct4 hESGSE21916 934693 935368 675 0
PHF8 HeLaGSE20725 915486 916506 1020 0
RARG MCF7GSE15244 933580 934210 630 0
RARG MCF7GSE15244 954607 955197 590 0
Sox2 hESGSE18292 934900 935117 217 0
TFAP2C MCF7GSE21234 916437 917016 579 0
TFAP2C MCF7GSE21234 918374 918951 577 0
TFAP2C MCF7GSE21234 927806 928278 472 0
TFAP2C MCF7GSE21234 945092 945898 806 0
TFAP2C MCF7GSE21234 947143 947853 710 0
TFAP2C MCF7GSE21234 956528 956930 402 0
TFAP2C MCF7GSE21234 962774 963271 497 0
TFAP2C MCF7GSE21234 976576 977206 630 0
USF1 HepG2E 930780 931025 245 0
USF2 HepG2E 930852 931025 173 0
hScc1 BcellGSE12603 951107 951392 285 0
hScc1 BcellGSE12603 954785 954920 135 0
hScc1 BcellGSE12603 968440 968757 317 0
hScc1 BcellGSE12603 970212 970666 454 0
hScc1 BcellGSE12603 983065 983546 481 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
3940 mRNA AP2A2 chr11 915880 1000919 2079 mRNA chr11 993791 995870 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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