AutismKB 2.0

Annotation Detail for DAPK1


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Basic Information Top
Gene Symbol:DAPK1 ( DAPK,DKFZp781I035 )
Gene Full Name: death-associated protein kinase 1
Band: 9q21.33
Quick LinksEntrez ID:1612; OMIM: 600831; Uniprot ID:DAPK1_HUMAN; ENSEMBL ID: ENSG00000196730; HGNC ID: 2674
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
308Phosphoserine; by autocatalysis.
Location(AA) Modifications Resource
289Phosphoserine (RSK-2;RSK
308Phosphoserine (by autocatalysis).Swiss-Prot 53.0
308Phosphoserine (DAPK1;DAPK
736Phosphoserine (MAPK1)Phospho.ELM 6.0
Location(AA) Modification Resource
12SulfotyrosineHMM predict
12Phosphotyrosine(Syk)HMM predict
13SulfotyrosineHMM predict
49Phosphothreonine(PKC)HMM predict
49Phosphothreonine(PKA)HMM predict
66Phosphoserine(PKG)HMM predict
83Phosphotyrosine(Syk)HMM predict
85N-linkedHMM predict
110Phosphoserine(CK1)HMM predict
112Phosphothreonine(CK2)HMM predict
228N-linkedHMM predict
233N-linkedHMM predict
265Phosphothreonine(PKC)HMM predict
289Phosphoserine(IKK)HMM predict
289Phosphoserine(PKG)HMM predict
289Phosphoserine(PKB)HMM predict
370Phosphotyrosine(INSR)HMM predict
380Phosphothreonine(CDK)HMM predict
482Phosphothreonine(MAPK)HMM predict
581Phosphothreonine(MAPK)HMM predict
614Phosphothreonine(MAPK)HMM predict
642Phosphothreonine(CK2)HMM predict
671Phosphothreonine(PKA)HMM predict
683O-linkedHMM predict
704Phosphothreonine(PKC)HMM predict
727Phosphoserine(PKB)HMM predict
727Phosphoserine(IKK)HMM predict
729N-linkedHMM predict
730Phosphoserine(CDK)HMM predict
736O-linkedHMM predict
736Phosphoserine(CDC2)HMM predict
740O-linkedHMM predict
743O-linkedHMM predict
848Phosphotyrosine(Syk)HMM predict
1066Phosphotyrosine(INSR)HMM predict
1216Phosphoserine(IKK)HMM predict
1234Phosphothreonine(PKC)HMM predict
1264Phosphothreonine(PKC)HMM predict
1293Phosphotyrosine(Abl)HMM predict
1316Phosphoserine(PKG)HMM predict
1358Phosphoserine(CDC2)HMM predict
1369Phosphothreonine(PKC)HMM predict
1415SerineHMM predict
1419Phosphoserine(IKK)HMM predict
1419Phosphoserine(CK1)HMM predict
1423Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004938
  • Location:chr9 89302575-89513367
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 89300696 89301088 392 1684
hScc1 BcellGSE12603 89302340 89302726 386 43
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 89520973 89521492 519 7865
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 89497501 89498119 618 0
CTCF CD4GSE12889 89467690 89467920 230 0
CTCF CD4GSE12889 89483369 89483750 381 0
CTCF CD4GSE12889 89489395 89489582 187 0
CTCF CD4SISSRdata 89467690 89467920 230 0
CTCF CD4SISSRdata 89483369 89483750 381 0
CTCF CD4SISSRdata 89489395 89489582 187 0
CTCF HelaGSE12889 89467697 89467960 263 0
ER MCF7GSE19013 89480152 89480821 669 0
FOXA1 MCF7GSE15244 89306530 89307758 1228 0
FOXA1 MCF7GSE15244 89374768 89376313 1545 0
FOXA1 MCF7GSE15244 89385474 89386644 1170 0
FOXA1 MCF7GSE15244 89479689 89481363 1674 0
Fos K562GSE19551 89320905 89321459 554 0
Fos K562GSE19551 89408745 89409189 444 0
FoxA1 MCF7MACSdata 89306609 89306939 330 0
FoxA1 MCF7MACSdata 89375456 89375925 469 0
FoxA1 MCF7MACSdata 89385932 89386104 172 0
Gata2 K562GSE18868 89356244 89356931 687 0
Gata2 K562GSE18868 89479281 89479762 481 0
H3K4me3 colorectalcancer 89303837 89304269 432 0
H3ac HepG2E 89490234 89490417 183 0
HIF1 HypoHepG2 89456493 89458005 1512 0
Myc K562GSE19551 89314431 89315170 739 0
Myc K562GSE19551 89340886 89341261 375 0
Myc K562GSE19551 89356345 89356820 475 0
Myc K562GSE19551 89479340 89479962 622 0
NFkBII GM12878GSE19485 89364521 89366027 1506 0
NRSF mAbJurkat 89464882 89465061 179 0
Nanog hESGSE18292 89483481 89483702 221 0
Oct1 H2O2-HelaGSE14283 89310061 89310094 33 0
Oct1 H2O2-HelaGSE14283 89381824 89381855 31 0
Oct1 HelaGSE14283 89310063 89310094 31 0
Oct1 HelaGSE14283 89381822 89381856 34 0
Oct1 HelaGSE14283 89489152 89489182 30 0
Oct4 hESGSE17917 89467571 89468034 463 0
PAX3-FKHR Rh4GSE19063 89384405 89386840 2435 0
PAX3-FKHR Rh4GSE19063 89404002 89405514 1512 0
RARA MCF7GSE15244 89374992 89375976 984 0
Rb QuiescentGSE19898 89461327 89461516 189 0
Rb SenescentGSE19898 89461272 89461569 297 0
STAT1 IFNSISSRdata 89467364 89468004 640 0
Sox2 hESGSE18292 89324420 89324648 228 0
TAF k562GSE8489 89303800 89304811 1011 0
TAF k562GSE8489 89341047 89341686 639 0
TFAP2C MCF7GSE21234 89306450 89307595 1145 0
TFAP2C MCF7GSE21234 89351192 89351866 674 0
TFAP2C MCF7GSE21234 89375510 89376226 716 0
TFAP2C MCF7GSE21234 89445185 89445580 395 0
TFAP2C MCF7GSE21234 89480044 89481149 1105 0
hScc1 BcellGSE12603 89303079 89303416 337 0
hScc1 BcellGSE12603 89328970 89329281 311 0
hScc1 BcellGSE12603 89456455 89457709 1254 0
hScc1 BcellGSE12603 89467640 89468769 1129 0
hScc1 BcellGSE12603 89501842 89502095 253 0
hScc1 BcellGSE12603 89511063 89511676 613 0
hScc1 CdLSGSE12603 89467640 89468201 561 0
hScc1 CdLSGSE12603 89483624 89483923 299 0
hScc1 G2GSE9613 89467640 89468382 742 0
hScc1 G2GSE9613 89483624 89484106 482 0
hScc1 G2GSE9613 89488600 89489788 1188 0
p130 QuiescentGSE19898 89398139 89398299 160 0
p130 shRbSenescentGSE19898 89461213 89461592 379 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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