AutismKB 2.0

Annotation Detail for C14orf21


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Basic Information Top
Gene Symbol:C14orf21 ( KIAA2021 )
Gene Full Name: chromosome 14 open reading frame 21
Band: 14q12
Quick LinksEntrez ID:161424; OMIM: NA; Uniprot ID:CN021_HUMAN; ENSEMBL ID: ENSG00000196943; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
7Phosphoserine.
Location(AA) Modifications Resource
7Phosphoserine.Swiss-Prot 53.0
7PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
7Phosphoserine(CDC2)HMM predict
21MethylarginineHMM predict
47O-linkedHMM predict
70Phosphoserine(PKG)HMM predict
103N-linkedHMM predict
117Phosphoserine(CDC2)HMM predict
229Phosphoserine(ATM)HMM predict
229PhosphoserineHMM predict
237Phosphothreonine(MAPK)HMM predict
309Phosphothreonine(PKC)HMM predict
313Phosphoserine(PKB)HMM predict
313Phosphoserine(CAMK2)HMM predict
378Phosphothreonine(CDK)HMM predict
383Phosphoserine(MAPK)HMM predict
383Phosphoserine(CDC2)HMM predict
455Phosphotyrosine(Syk)HMM predict
456SulfotyrosineHMM predict
516Phosphoserine(IKK)HMM predict
520Phosphoserine(IKK)HMM predict
520Phosphoserine(CDC2)HMM predict
533Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_174913
  • Location:chr14 23838937-23844213
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 23838397 23839293 896 93
KLF4 hESGSE17917 23838765 23839006 241 52
Myc K562GSE19551 23838569 23839174 605 66
Oct1 H2O2-HelaGSE14283 23838812 23838840 28 112
P300 T0-glioblastomaGSE21026 23838418 23839128 710 165
p130 QuiescentGSE19898 23838699 23839066 367 55
p130 SenescentGSE19898 23838767 23839021 254 44
p130 shRbSenescentGSE19898 23838732 23839022 290 61
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 23839708 23839740 32 0
H3K4me3 colorectalcancer 23839715 23840149 434 0
H3ac HepG2E 23839136 23843028 3892 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018