AutismKB 2.0

Annotation Detail for DBH


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Basic Information Top
Gene Symbol:DBH ( DBM )
Gene Full Name: dopamine beta-hydroxylase (dopamine beta-monooxygenase)
Band: 9q34.2
Quick LinksEntrez ID:1621; OMIM: 609312; Uniprot ID:DOPO_HUMAN; ENSEMBL ID: ENSG00000123454; HGNC ID: 2689
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
64N-linked (GlcNAc...) (Potential).
184N-linked (GlcNAc...).
Location(AA) Modifications Resource
50N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
170N-linked (GlcNAc...).Swiss-Prot 53.0
330N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
552N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
44Phosphoserine(CK1)HMM predict
50N-linkedHMM predict
170N-linkedHMM predict
211Phosphoserine(ATM)HMM predict
313Phosphotyrosine(EGFR)HMM predict
426Phosphotyrosine(Jak)HMM predict
552N-linkedHMM predict
589Phosphoserine(IKK)HMM predict
589O-linkedHMM predict
589Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000787
  • Location:chr9 135491305-135514286
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 135511450 135511693 243 0
CTCF CD4SISSRdata 135511450 135511693 243 0
Rb shRbQuiescentGSE19898 135498310 135498564 254 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
27168 mRNA DBH chr9 133531038 133554020 118 mRNA LOC138948 chr9 133549261 133551989Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018