AutismKB 2.0

Annotation Detail for DCC


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Basic Information Top
Gene Symbol:DCC ( CRC18,CRCR1,IGDCC1 )
Gene Full Name: deleted in colorectal carcinoma
Band: 18q21.2
Quick LinksEntrez ID:1630; OMIM: 120470; Uniprot ID:DCC_HUMAN; ENSEMBL ID: ENSG00000187323; HGNC ID: 2701
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
94N-linked (GlcNAc...) (Potential).
299N-linked (GlcNAc...) (Potential).
318N-linked (GlcNAc...) (Potential).
478N-linked (GlcNAc...) (Potential).
628N-linked (GlcNAc...) (Potential).
702N-linked (GlcNAc...) (Potential).
868Phosphoserine.
1073Phosphoserine.
1074Phosphothreonine.
Location(AA) Modifications Resource
94N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
299N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
318N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
478N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
628N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
702N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
115Phosphotyrosine(INSR)HMM predict
144Phosphoserine(IKK)HMM predict
299N-linkedHMM predict
343Phosphotyrosine(INSR)HMM predict
425O-linkedHMM predict
426O-linkedHMM predict
478N-linkedHMM predict
514Phosphoserine(ATM)HMM predict
538O-linkedHMM predict
540Phosphoserine(CDK)HMM predict
540Phosphoserine(IKK)HMM predict
540Phosphoserine(CDC2)HMM predict
543Phosphoserine(IKK)HMM predict
553Phosphotyrosine(Abl)HMM predict
619O-linkedHMM predict
665Phosphothreonine(PKA)HMM predict
665Phosphothreonine(PKC)HMM predict
666Phosphothreonine(PKA)HMM predict
666Phosphothreonine(PKC)HMM predict
702N-linkedHMM predict
715Phosphothreonine(MAPK)HMM predict
723Phosphoserine(ATM)HMM predict
768Phosphotyrosine(Abl)HMM predict
780Phosphotyrosine(Syk)HMM predict
788Phosphoserine(CK1)HMM predict
816Phosphoserine(IKK)HMM predict
826SulfotyrosineHMM predict
863Phosphoserine(IKK)HMM predict
882Phosphothreonine(PKC)HMM predict
901O-linkedHMM predict
902O-linkedHMM predict
906O-linkedHMM predict
928Phosphoserine(CK1)HMM predict
932Phosphoserine(IKK)HMM predict
945O-linkedHMM predict
945Phosphothreonine(PKC)HMM predict
1027Phosphoserine(PKG)HMM predict
1062Phosphotyrosine(INSR)HMM predict
1091Phosphothreonine(CDC2)HMM predict
1091Phosphothreonine(CDK)HMM predict
1126Phosphoserine(PKA)HMM predict
1126Phosphoserine(PKG)HMM predict
1126Phosphoserine(PKB)HMM predict
1135Phosphothreonine(PKA)HMM predict
1144Phosphoserine(PKG)HMM predict
1144Phosphoserine(PKA)HMM predict
1192PhosphoserineHMM predict
1192Phosphoserine(ATM)HMM predict
1192Phosphoserine(IKK)HMM predict
1194Phosphoserine(CK1)HMM predict
1204Phosphoserine(IKK)HMM predict
1204Phosphoserine(CK1)HMM predict
1206Phosphoserine(IKK)HMM predict
1255O-linkedHMM predict
1272SulfotyrosineHMM predict
1278Phosphothreonine(PKC)HMM predict
1298Phosphoserine(ATM)HMM predict
1300Phosphoserine(PKG)HMM predict
1300Phosphoserine(IKK)HMM predict
1302O-linkedHMM predict
1302Phosphoserine(IKK)HMM predict
1316Phosphoserine(ATM)HMM predict
1321Phosphoserine(CK1)HMM predict
1322Phosphoserine(CK1)HMM predict
1323Phosphoserine(CK1)HMM predict
1328O-linkedHMM predict
1328O-linkedHMM predict
1339Phosphothreonine(PKA)HMM predict
1339Phosphothreonine(CDK)HMM predict
1364Phosphothreonine(CDK)HMM predict
1364Phosphothreonine(MAPK)HMM predict
1368Phosphoserine(ATM)HMM predict
1377Phosphothreonine(CDK)HMM predict
1406Phosphoserine(CK1)HMM predict
1406O-linkedHMM predict
1420Phosphotyrosine(Syk)HMM predict
1420Phosphotyrosine(Abl)HMM predict
1436MethionineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005215
  • Location:chr18 48120568-49311779
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF JurkatGSE12889 48120281 48120439 158 209
hScc1 BcellGSE12603 48120172 48120669 497 148
hScc1 CdLSGSE12603 48120030 48120694 664 207
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
AR prostate-cancerGSE14092 48572667 48573770 1103 0
CBP T0-glioblastomaGSE21026 48563529 48563933 404 0
CBP T0-glioblastomaGSE21026 48572635 48573406 771 0
CBP T0-glioblastomaGSE21026 48582696 48583056 360 0
CBP T0-glioblastomaGSE21026 48730954 48731508 554 0
CBP T30-glioblastomaGSE21026 48572743 48573371 628 0
CTCF JurkatGSE12889 48573100 48573249 149 0
ER E2-MCF7GSE14664 49018570 49018603 33 0
ERG prostate-cancerGSE14092 48572956 48573739 783 0
Fos K562GSE19551 48573024 48573328 304 0
H3K27me3 colorectalcancer 48120066 48122675 2609 0
IGF1R DFBGSE23792 48572663 48573406 743 0
Jun K562GSE19551 48573000 48573298 298 0
Myc K562GSE19551 48573089 48573324 235 0
NRSF JurkatGSE13047 48798992 48799679 687 0
NRSF JurkatGSE13047 49048882 49049249 367 0
NRSF JurkatSISSRdata 48573090 48573272 182 0
NRSF JurkatSISSRdata 48799080 48799435 355 0
NRSF mAbJurkat 48799713 48800005 292 0
NRSF mAbJurkat 48800674 48802262 1588 0
NRSF mAbJurkat 49048931 49050631 1700 0
NRSF mAbJurkat 49290404 49291793 1389 0
NRSF-mono JurkatQuESTdata 48798997 48799546 549 0
NRSF-mono JurkatQuESTdata 49048840 49049165 325 0
NRSF-mono JurkatQuESTdata 49290309 49290646 337 0
NRSF-poly JurkatQuESTdata 48799245 48799600 355 0
NRSF-poly JurkatQuESTdata 49048943 49049249 306 0
Nanog ESGSE20650 48573124 48573293 169 0
Nanog ESGSE20650 48588203 48588614 411 0
Nanog hESGSE18292 48562352 48562832 480 0
Nanog hESGSE18292 48607590 48607797 207 0
Nanog hESGSE18292 48684300 48684653 353 0
Nanog hESGSE18292 48972042 48972498 456 0
Nanog hESGSE18292 49252366 49252618 252 0
Oct1 H2O2-HelaGSE14283 48157144 48157173 29 0
Oct1 H2O2-HelaGSE14283 48159830 48159856 26 0
Oct1 H2O2-HelaGSE14283 48171769 48171801 32 0
Oct1 H2O2-HelaGSE14283 48173715 48173744 29 0
Oct1 H2O2-HelaGSE14283 48284751 48284779 28 0
Oct1 H2O2-HelaGSE14283 48321649 48321678 29 0
Oct1 H2O2-HelaGSE14283 48335946 48335991 45 0
Oct1 H2O2-HelaGSE14283 48423778 48423805 27 0
Oct1 H2O2-HelaGSE14283 48432382 48432422 40 0
Oct1 H2O2-HelaGSE14283 48486349 48486379 30 0
Oct1 H2O2-HelaGSE14283 48715214 48715251 37 0
Oct1 H2O2-HelaGSE14283 48767963 48767991 28 0
Oct1 H2O2-HelaGSE14283 48854197 48854235 38 0
Oct1 H2O2-HelaGSE14283 48869633 48869659 26 0
Oct1 H2O2-HelaGSE14283 48977393 48977432 39 0
Oct1 HelaGSE14283 48135753 48135859 106 0
Oct1 HelaGSE14283 48157137 48157173 36 0
Oct1 HelaGSE14283 48171770 48171801 31 0
Oct1 HelaGSE14283 48327891 48327936 45 0
Oct1 HelaGSE14283 48335946 48335991 45 0
Oct1 HelaGSE14283 48380480 48380510 30 0
Oct1 HelaGSE14283 48423766 48423806 40 0
Oct1 HelaGSE14283 48432391 48432421 30 0
Oct1 HelaGSE14283 48715214 48715251 37 0
Oct1 HelaGSE14283 48771340 48771371 31 0
Oct1 HelaGSE14283 48854197 48854235 38 0
Oct1 HelaGSE14283 48869633 48869659 26 0
Oct1 HelaGSE14283 48870548 48870582 34 0
Oct1 HelaGSE14283 48977397 48977432 35 0
Oct1 HelaGSE14283 49247978 49248012 34 0
Oct4 ESGSE20650 48573120 48573290 170 0
P300 T0-glioblastomaGSE21026 48572991 48573409 418 0
P300 T30-glioblastomaGSE21026 48572976 48573645 669 0
Pol3 K562GSE19551 48572986 48573377 391 0
STAT1 IFNSISSRdata 48573050 48573353 303 0
TAF HelaGSE8489 48804159 48804370 211 0
hScc1 BcellGSE12603 48123635 48123837 202 0
hScc1 CdLSGSE12603 48123349 48124108 759 0
hScc1 CdLSGSE12603 48684014 48684670 656 0
hScc1 CdLSGSE12603 49160206 49160947 741 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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