AutismKB 2.0

Annotation Detail for DENND2C


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Basic Information Top
Gene Symbol:DENND2C ( DKFZp686G0351,DKFZp686N1631,DKFZp779P1149,FLJ37099,dJ1156J9.1 )
Gene Full Name: DENN/MADD domain containing 2C
Band: 1p13.2
Quick LinksEntrez ID:163259; OMIM: NA; Uniprot ID:DEN2C_HUMAN; ENSEMBL ID: ENSG00000175984; HGNC ID: 24748
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
102Phosphotyrosine(Syk)HMM predict
102Phosphotyrosine(Jak)HMM predict
102Phosphotyrosine(INSR)HMM predict
110N-linkedHMM predict
115N-linkedHMM predict
171Phosphoserine(CK1)HMM predict
195Phosphotyrosine(Syk)HMM predict
195Phosphotyrosine(SRC)HMM predict
196Phosphoserine(CK1)HMM predict
196Phosphoserine(SRC)HMM predict
240N-linkedHMM predict
241N-linkedHMM predict
251Phosphoserine(ATM)HMM predict
287Phosphothreonine(PKC)HMM predict
302SulfotyrosineHMM predict
310Phosphotyrosine(EGFR)HMM predict
310Phosphotyrosine(INSR)HMM predict
310Phosphotyrosine(Syk)HMM predict
310SulfotyrosineHMM predict
315SulfotyrosineHMM predict
322Phosphotyrosine(SRC)HMM predict
322Phosphotyrosine(Syk)HMM predict
402Phosphothreonine(PKC)HMM predict
447N-linkedHMM predict
449Phosphoserine(CK2)HMM predict
453Phosphotyrosine(Jak)HMM predict
477Phosphothreonine(CDK)HMM predict
524Phosphotyrosine(Syk)HMM predict
524Phosphotyrosine(Jak)HMM predict
527Phosphoserine(CAMK2)HMM predict
617Phosphoserine(IKK)HMM predict
641Phosphothreonine(PKC)HMM predict
675S-palmitoylHMM predict
679S-palmitoylHMM predict
777Phosphoserine(CK2)HMM predict
777PhosphoserineHMM predict
777Phosphoserine(CK2)HMM predict
807N-linkedHMM predict
809Phosphoserine(ATM)HMM predict
836N-linkedHMM predict
857Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_198459
  • Location:chr1 114926992-115014254
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 115015630 115015841 211 1481
CTCF CD4SISSRdata 115015630 115015841 211 1481
PHF8 Hs68plusFBSGSE20725 115013562 115015200 1638 127
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TAF k562GSE8489 114926468 114926758 290 380
p130 SenescentGSE19898 114926377 114926570 193 519
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 115013880 115014342 462 0
GABP k562GSE8489 114926468 114927612 1144 0
GABP k562GSE8489 115012126 115013359 1233 0
H3K4me3 colorectalcancer 115013064 115013765 701 0
H3ac HepG2E 114958657 114958829 172 0
Oct1 H2O2-HelaGSE14283 114933219 114933265 46 0
Oct1 HelaGSE14283 114933220 114933265 45 0
RARA MCF7GSE15244 114927438 114927612 174 0
RARA MCF7GSE15244 115013064 115013839 775 0
hScc1 BcellGSE12603 115013693 115014305 612 0
p63 keratinocytesGSE17611 114954757 114955486 729 0
p63 keratinocytesGSE17611 114962428 114963134 706 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
1330 EST chr1 114854903 114855784 242 mRNA FLJ37099 chr1 114837508 114924774Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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