AutismKB 2.0

Annotation Detail for DDB2


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Basic Information Top
Gene Symbol:DDB2 ( DDBB,FLJ34321,UV-DDB2 )
Gene Full Name: damage-specific DNA binding protein 2, 48kDa
Band: 11p11.2
Quick LinksEntrez ID:1643; OMIM: 600811; Uniprot ID:DDB2_HUMAN; ENSEMBL ID: ENSG00000134574; HGNC ID: 2718
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
24Phosphoserine.
26Phosphoserine.
274DWD box.
278N6-acetyllysine.
Location(AA) Modifications Resource
24Phosphoserine.Swiss-Prot 53.0
24PhosphoserinePhospho.ELM 6.0
26Phosphoserine.Swiss-Prot 53.0
26PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
24Phosphoserine(PKG)HMM predict
26Phosphoserine(CDC2)HMM predict
26Phosphoserine(IKK)HMM predict
115Phosphothreonine(PKA)HMM predict
122Phosphothreonine(CDK)HMM predict
246Phosphothreonine(PKA)HMM predict
305Phosphothreonine(PKC)HMM predict
392Phosphoserine(CK1)HMM predict
413TyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000107
  • Location:chr11 47193088-47217338
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 47182419 47182876 457 10441
FoxA1 MCF7MACSdata 47182396 47182614 218 10584
Oct1 HelaGSE14283 47179765 47179811 46 13301
RARA MCF7GSE15244 47182419 47182876 457 10441
RARG MCF7GSE15244 47191010 47191318 308 1925
TAF HelaGSE8489 47192333 47192595 262 625
TFAP2C MCF7GSE21234 47190823 47191585 762 1885
USF1 HepG2E 47192333 47192595 262 625
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 47212188 47212332 144 0
CTCF CD4SISSRdata 47212188 47212332 144 0
FOXA1 DLD1GSE12801 47212433 47213118 685 0
FOXA1 MCF7GSE15244 47192990 47193848 858 0
FOXA1 MCF7GSE15244 47194445 47195193 748 0
FOXA1 MCF7GSE15244 47212245 47213278 1033 0
H3K4me3 colorectalcancer 47193391 47194225 834 0
H3ac HepG2E 47193067 47195193 2126 0
H3ac HepG2E 47196115 47196987 872 0
LIN9 G0GSE7516 47192990 47193779 789 0
LIN9 SGSE7516 47192954 47193742 788 0
PolII HeLaGSE12783 47191983 47195327 3344 0
RARA MCF7GSE15244 47193255 47193881 626 0
RARA MCF7GSE15244 47194410 47195056 646 0
RARG MCF7GSE15244 47193255 47193917 662 0
RARG MCF7GSE15244 47194445 47195127 682 0
Rb QuiescentGSE19898 47193003 47193713 710 0
Rb SenescentGSE19898 47192915 47193603 688 0
Rb shRbSenescenceGSE19898 47192906 47193327 421 0
TAF HelaGSE8489 47192918 47194305 1387 0
USF1 HepG2E 47192918 47194225 1307 0
p130 QuiescentGSE19898 47193013 47193709 696 0
p130 SenescentGSE19898 47192923 47193622 699 0
p130 shRbQuiescentGSE19898 47192731 47193625 894 0
p130 shRbSenescentGSE19898 47192904 47193668 764 0
p130 G0GSE7516 47193102 47193848 746 0
p130 SGSE7516 47193067 47193707 640 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018