Annotation Detail for DDC
Basic Information Top
| Gene Symbol: | DDC ( AADC ) |
|---|---|
| Gene Full Name: | dopa decarboxylase (aromatic L-amino acid decarboxylase) |
| Band: | 7p12.2-p12.1 |
| Quick Links | Entrez ID:1644; OMIM: 107930; Uniprot ID:DDC_HUMAN; ENSEMBL ID: ENSG00000132437; HGNC ID: 2719 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 303 | N6-(pyridoxal phosphate)lysine. | |
| Location(AA) | Modifications | Resource |
|---|
| Location(AA) | Modification | Resource |
|---|---|---|
| 30 | Phosphotyrosine(EGFR) | HMM predict |
| 30 | Phosphotyrosine(Syk) | HMM predict |
| 108 | Phosphoserine(CDC2) | HMM predict |
| 220 | Phosphoserine(PKG) | HMM predict |
| 246 | O-linked | HMM predict |
| 320 | Phosphothreonine(PKA) | HMM predict |
| 332 | Phosphotyrosine(Jak) | HMM predict |
- RefSeq ID: NM_000790
- Location:chr7 50493629-50596244
- strand:-
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 50596871 | 50597370 | 499 | 876 |
| H3ac | HepG2 | E | 50599998 | 50600645 | 647 | 4077 |
| Oct1 | Hela | GSE14283 | 50607916 | 50607943 | 27 | 11685 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CBP | Jurkat | GSE17954 | 50542608 | 50544320 | 1712 | 0 |
| CBP | T30-glioblastoma | GSE21026 | 50569857 | 50570962 | 1105 | 0 |
| CTCF | CD4 | GSE12889 | 50503135 | 50503487 | 352 | 0 |
| CTCF | CD4 | SISSRdata | 50503135 | 50503487 | 352 | 0 |
| CTCF | G2 | GSE9613 | 50498274 | 50498463 | 189 | 0 |
| CTCF | G2 | GSE9613 | 50503081 | 50503627 | 546 | 0 |
| CTCF | G2 | GSE9613 | 50508685 | 50508971 | 286 | 0 |
| CTCF | G2 | GSE9613 | 50514730 | 50514899 | 169 | 0 |
| CTCF | G2 | GSE9613 | 50537320 | 50537615 | 295 | 0 |
| CTCF | G2 | GSE9613 | 50569817 | 50570278 | 461 | 0 |
| CTCF | G2 | GSE9613 | 50573965 | 50574351 | 386 | 0 |
| CTCF | G2 | GSE9613 | 50575808 | 50576367 | 559 | 0 |
| CTCF | G2 | GSE9613 | 50594204 | 50594590 | 386 | 0 |
| CTCF | G2 | GSE9613 | 50595843 | 50596061 | 218 | 0 |
| Fos | K562 | GSE19551 | 50532050 | 50532681 | 631 | 0 |
| Fos | K562 | GSE19551 | 50569847 | 50570485 | 638 | 0 |
| Gata1 | K562 | GSE18868 | 50532206 | 50532733 | 527 | 0 |
| Gata2 | K562 | GSE18868 | 50531785 | 50532859 | 1074 | 0 |
| Gata2 | K562 | GSE18868 | 50593444 | 50594048 | 604 | 0 |
| Myc | K562 | GSE19551 | 50503083 | 50503594 | 511 | 0 |
| NRSF | Jurkat | GSE13047 | 50587764 | 50588714 | 950 | 0 |
| NRSF | mAb | Jurkat | 50581934 | 50582257 | 323 | 0 |
| NRSF | mAb | Jurkat | 50586071 | 50586396 | 325 | 0 |
| NRSF | mAb | Jurkat | 50587039 | 50588624 | 1585 | 0 |
| NRSF | mAb | Jurkat | 50588991 | 50589257 | 266 | 0 |
| NRSF | mAb | Jurkat | 50589612 | 50590545 | 933 | 0 |
| NRSF | mAb | Jurkat | 50591057 | 50591335 | 278 | 0 |
| NRSF | mAb | Jurkat | 50591720 | 50594170 | 2450 | 0 |
| NRSF-mono | Jurkat | QuESTdata | 50587437 | 50588690 | 1253 | 0 |
| NRSF | pAb | Jurkat | 50587039 | 50588624 | 1585 | 0 |
| NRSF | pAb | Jurkat | 50588991 | 50589257 | 266 | 0 |
| NRSF-poly | Jurkat | QuESTdata | 50587901 | 50588648 | 747 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 50564570 | 50564606 | 36 | 0 |
| Oct1 | Hela | GSE14283 | 50564570 | 50564618 | 48 | 0 |
| P300 | T0-glioblastoma | GSE21026 | 50569803 | 50570574 | 771 | 0 |
| P300 | T30-glioblastoma | GSE21026 | 50569722 | 50570790 | 1068 | 0 |
| RARA | MCF7 | GSE15244 | 50566428 | 50567369 | 941 | 0 |
| Rb | Growing | GSE19898 | 50503320 | 50503624 | 304 | 0 |
| Rb | Quiescent | GSE19898 | 50503353 | 50503700 | 347 | 0 |
| Rb | Senescent | GSE19898 | 50503189 | 50503745 | 556 | 0 |
| Rb | shRbQuiescent | GSE19898 | 50503316 | 50503577 | 261 | 0 |
| Rb | shRbSenescence | GSE19898 | 50503319 | 50503589 | 270 | 0 |
| TFAP2C | MCF7 | GSE21234 | 50527734 | 50528759 | 1025 | 0 |
| hScc1 | Bcell | GSE12603 | 50503120 | 50503796 | 676 | 0 |
| hScc1 | Bcell | GSE12603 | 50568802 | 50569028 | 226 | 0 |
| hScc1 | CdLS | GSE12603 | 50503120 | 50503796 | 676 | 0 |
| hScc1 | G2 | GSE9613 | 50503045 | 50503585 | 540 | 0 |
| hScc1 | G2 | GSE9613 | 50537284 | 50537615 | 331 | 0 |
| p130 | Quiescent | GSE19898 | 50503315 | 50503534 | 219 | 0 |
| p130 | Quiescent | GSE19898 | 50569901 | 50570137 | 236 | 0 |
| p130 | shRbSenescent | GSE19898 | 50503222 | 50503538 | 316 | 0 |
Validated miRNA targets| Cluster ID | Plue Type | Plus Gene Name | Plus Chromosome | Plus Start | Plus End | Overlap Length | Minus Type | Minus Gene Name | Minus Chromosome | Minus Star | Minus End | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 23994 | mRNA | chr7 | 50373665 | 50385370 | 114 | mRNA | DDC | chr7 | 50300344 | 50402960 | Sense/Antisense (SA) pairs | |