AutismKB 2.0

Annotation Detail for DDT


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Basic Information Top
Gene Symbol:DDT ( DDCT )
Gene Full Name: D-dopachrome tautomerase
Band: 22q11.23
Quick LinksEntrez ID:1652; OMIM: 602750; Uniprot ID:DOPD_HUMAN; ENSEMBL ID: ENSG00000099977; HGNC ID: 2732
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylproline (By similarity).
Location(AA) Modifications Resource
2N-acetylproline (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
39N-linkedHMM predict
74N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001355
  • Location:chr22 22643561-22652018
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 22638412 22639186 774 4763
ETS1 JurkatGSE17954 22638349 22639494 1145 4640
FOXA1 MCF7GSE15244 22638412 22639145 733 4783
FOXA1 MCF7GSE15244 22639690 22640457 767 3488
GABP k562GSE8489 22639801 22640457 656 3433
H3K4me3 colorectalcancer 22639455 22640457 1002 3606
H3ac HepG2E 22638412 22640457 2045 4127
HIF1 HypoHepG2 22638412 22639260 848 4726
RARA MCF7GSE15244 22638412 22639068 656 4822
RARA MCF7GSE15244 22639767 22640457 690 3450
RARG MCF7GSE15244 22638480 22639105 625 4769
RARG MCF7GSE15244 22641437 22642268 831 1709
TFAP2C MCF7GSE21234 22638909 22639206 297 4504
USF1 HepG2E 22638412 22640457 2045 4127
USF1 HepG2E 22642062 22642595 533 1233
USF2 HepG2E 22638412 22640457 2045 4127
hScc1 BcellGSE12603 22638922 22639719 797 4241
hScc1 CdLSGSE12603 22638412 22638693 281 5009
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 22646399 22647267 868 0
ETS1 JurkatGSE17954 22646255 22647190 935 0
FOXA1 MCF7GSE15244 22646059 22647267 1208 0
H3K27me3 colorectalcancer 22649692 22650562 870 0
H3K27me3 colorectalcancer 22651058 22651239 181 0
H3K4me2 HCT116GSE10453 22645221 22645913 692 0
H3K4me3 colorectalcancer 22645221 22646455 1234 0
H3ac HepG2E 22645221 22646092 871 0
H3ac HepG2E 22646347 22647267 920 0
H3ac HepG2E 22651058 22651882 824 0
HIF1 HypoHepG2 22646399 22646942 543 0
RARG MCF7GSE15244 22645221 22645710 489 0
RARG MCF7GSE15244 22646059 22647267 1208 0
USF1 HepG2E 22645221 22647267 2046 0
USF2 HepG2E 22646399 22647267 868 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-132 hsa-mir-132 17 20300990
hsa-miR-132* hsa-mir-132 17 20300990
hsa-miR-155 hsa-mir-155 21 20356498
hsa-miR-155* hsa-mir-155 21 20356498
hsa-miR-205 hsa-mir-205 1 18719201
hsa-miR-21 hsa-mir-21 17 18719201
hsa-miR-21* hsa-mir-21 17 18719201
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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