AutismKB 2.0

Annotation Detail for DDX3X


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Basic Information Top
Gene Symbol:DDX3X ( DBX,DDX14,DDX3,HLP2 )
Gene Full Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
Band: Xp11.4
Quick LinksEntrez ID:1654; OMIM: 300160; Uniprot ID:DDX3X_HUMAN; ENSEMBL ID: ENSG00000215301; HGNC ID: 2745
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylserine.
69Phosphotyrosine.
74Phosphoserine.
76Phosphoserine.
78Phosphoserine.
104Phosphotyrosine.
118N6-acetyllysine.
125Phosphoserine.
208Q motif.
343Phosphotyrosine.
350DEAD box.
590Phosphoserine.
594Phosphoserine.
612Phosphoserine.
Location(AA) Modifications Resource
2N-acetylserine.Swiss-Prot 53.0
68PhosphotyrosinePhospho.ELM 6.0
69Phosphotyrosine.Swiss-Prot 53.0
73PhosphoserinePhospho.ELM 6.0
74Phosphoserine (By similarity).Swiss-Prot 53.0
103PhosphotyrosinePhospho.ELM 6.0
104Phosphotyrosine.Swiss-Prot 53.0
203Phosphothreonine (CDK1)Phospho.ELM 6.0
322Phosphothreonine (CDK1)Phospho.ELM 6.0
342PhosphotyrosinePhospho.ELM 6.0
343Phosphotyrosine.Swiss-Prot 53.0
Location(AA) Modification Resource
22N-linkedHMM predict
23Phosphoserine(CK1)HMM predict
26N-linkedHMM predict
28O-linkedHMM predict
28Phosphoserine(IKK)HMM predict
38Phosphotyrosine(INSR)HMM predict
82Phosphoserine(PKB)HMM predict
90Phosphoserine(CK1)HMM predict
93MethylarginineHMM predict
99MethylarginineHMM predict
104Phosphotyrosine(Syk)HMM predict
104Phosphotyrosine(INSR)HMM predict
131Phosphoserine(CK2)HMM predict
137Phosphoserine(IKK)HMM predict
163Phosphotyrosine(Syk)HMM predict
201Phosphothreonine(PKA)HMM predict
204Phosphothreonine(PKA)HMM predict
283Phosphotyrosine(EGFR)HMM predict
290Phosphoserine(PKC)HMM predict
290Phosphoserine(PKB)HMM predict
343Phosphotyrosine(Syk)HMM predict
414N-linkedHMM predict
436N-linkedHMM predict
466Phosphotyrosine(INSR)HMM predict
466Phosphotyrosine(Syk)HMM predict
551N-linkedHMM predict
590Phosphoserine(PKB)HMM predict
606Phosphoserine(PKB)HMM predict
606Phosphoserine(IKK)HMM predict
612Phosphoserine(IKK)HMM predict
614Phosphoserine(CK1)HMM predict
619Phosphoserine(CK1)HMM predict
623Phosphoserine(CK1)HMM predict
632MethylarginineHMM predict
639Phosphotyrosine(INSR)HMM predict
645SerineHMM predict
648Phosphotyrosine(INSR)HMM predict
648TyrosineHMM predict
648SulfotyrosineHMM predict
654Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001356
  • Location:chrX 41077594-41094465
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 41066300 41066511 211 11189
CTCF G2GSE9613 41066917 41067372 455 10450
TAF k562GSE8489 41075227 41075955 728 2004
TAF k562GSE8489 41076710 41076987 277 746
hScc1 BcellGSE12603 41066300 41066589 289 11150
hScc1 BcellGSE12603 41077289 41077824 535 38
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog ESGSE20650 41111691 41112134 443 17447
Nanog hESGSE18292 41111653 41111944 291 17333
PolII HeLaGSE12783 41093642 41097458 3816 1085
VDR GM10855-stimGSE22484 41093685 41097556 3871 1155
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 41077313 41079609 2296 0
H3K4me3 colorectalcancer 41079936 41080336 400 0
H3ac HepG2E 41077758 41080336 2578 0
PHF8 HeLaGSE20725 41076955 41079286 2331 0
PHF8 Hs68minusFBSGSE20725 41077974 41078996 1022 0
Pol2 GM12878GSE19551 41076798 41079810 3012 0
TAF k562GSE8489 41077677 41078589 912 0
TAF k562GSE8489 41079350 41080615 1265 0
USF1 HepG2E 41077677 41078393 716 0
USF2 HepG2E 41077712 41078393 681 0
hScc1 G2GSE9613 41076710 41079649 2939 0
p130 QuiescentGSE19898 41077423 41079245 1822 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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