AutismKB 2.0

Annotation Detail for PRICKLE2


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Basic Information Top
Gene Symbol:PRICKLE2 ( DKFZp686D143,DKFZp686H1748,DKFZp686M031 )
Gene Full Name: prickle homolog 2 (Drosophila)
Band: 3p14.1
Quick LinksEntrez ID:166336; OMIM: 608501; Uniprot ID:PRIC2_HUMAN; ENSEMBL ID: ENSG00000163637; HGNC ID: 20340
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
92Phosphoserine (By similarity).
543Phosphoserine (By similarity).
695Phosphoserine (By similarity).
731Phosphoserine (By similarity).
806Phosphoserine (By similarity).
841Cysteine methyl ester (Probable).
Location(AA) Modifications Resource
92Phosphoserine (By similarity).Swiss-Prot 53.0
543Phosphoserine (By similarity).Swiss-Prot 53.0
695Phosphoserine (By similarity).Swiss-Prot 53.0
731Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
23N-linkedHMM predict
25Phosphothreonine(CK2)HMM predict
26Phosphoserine(CK2)HMM predict
30Phosphoserine(IKK)HMM predict
66Phosphoserine(CDC2)HMM predict
234Phosphotyrosine(EGFR)HMM predict
243S-palmitoylHMM predict
244S-palmitoylHMM predict
285S-palmitoylHMM predict
311Phosphoserine(PKG)HMM predict
317N-linkedHMM predict
322Phosphoserine(ATM)HMM predict
382Phosphoserine(CDK)HMM predict
383Phosphoserine(ATM)HMM predict
403SulfotyrosineHMM predict
410N-linkedHMM predict
429Phosphoserine(CDC2)HMM predict
454Phosphoserine(PKA)HMM predict
454O-linkedHMM predict
483Phosphotyrosine(INSR)HMM predict
483Phosphotyrosine(Syk)HMM predict
484Phosphoserine(CK1)HMM predict
488Phosphoserine(ATM)HMM predict
490Phosphoserine(IKK)HMM predict
492Phosphoserine(CK1)HMM predict
534Phosphothreonine(MAPK)HMM predict
539Phosphothreonine(MAPK)HMM predict
551N-linkedHMM predict
607Phosphoserine(CK1)HMM predict
614Phosphotyrosine(SRC)HMM predict
614Phosphotyrosine(Syk)HMM predict
674Phosphothreonine(PKC)HMM predict
674Phosphothreonine(PKA)HMM predict
675Phosphoserine(PKA)HMM predict
723Phosphotyrosine(Syk)HMM predict
723SulfotyrosineHMM predict
731Phosphoserine(IKK)HMM predict
731Phosphoserine(PKA)HMM predict
776O-linkedHMM predict
780Phosphoserine(CK1)HMM predict
780Phosphoserine(CDC2)HMM predict
784Phosphoserine(CK1)HMM predict
784Phosphoserine(CK2)HMM predict
784Phosphoserine(ATM)HMM predict
789Phosphotyrosine(INSR)HMM predict
839LysineHMM predict
841S-farnesylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_198859
  • Location:chr3 64054590-64186170
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 64199361 64200545 1184 13783
CTCF G2GSE9613 64199759 64200120 361 13769
FOXA1 MCF7GSE15244 64203080 64203860 780 17300
FOXA1 MCF7GSE15244 64204787 64205476 689 18961
P300 T30-glioblastomaGSE21026 64199169 64200563 1394 13696
RARA MCF7GSE15244 64187935 64188262 327 1928
RARA MCF7GSE15244 64192094 64193210 1116 6482
RARA MCF7GSE15244 64203080 64203860 780 17300
RARA MCF7GSE15244 64204612 64206655 2043 19463
RARG MCF7GSE15244 64203305 64203860 555 17412
RARG MCF7GSE15244 64204612 64205628 1016 18950
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 64044302 64044481 179 10199
FOXA1 MCF7GSE15244 64049331 64049599 268 5126
Oct1 H2O2-HelaGSE14283 64042420 64042450 30 12156
Oct1 H2O2-HelaGSE14283 64054111 64054156 45 457
Oct1 HelaGSE14283 64042417 64042449 32 12158
Oct1 HelaGSE14283 64054075 64054157 82 475
Oct4 ESGSE20650 64044265 64044687 422 10115
RARA MCF7GSE15244 64037228 64037525 297 17214
RARA MCF7GSE15244 64046913 64048281 1368 6994
RARA MCF7GSE15244 64049146 64050081 935 4977
RARG MCF7GSE15244 64040601 64041316 715 13632
RARG MCF7GSE15244 64047092 64048210 1118 6940
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 64087908 64088090 182 0
CTCF G2GSE9613 64093931 64094152 221 0
FOXA1 MCF7GSE15244 64065037 64066136 1099 0
FOXA1 MCF7GSE15244 64068931 64069250 319 0
FOXA1 MCF7GSE15244 64082708 64083523 815 0
FOXA1 MCF7GSE15244 64091702 64092742 1040 0
FOXA1 MCF7GSE15244 64093702 64095385 1683 0
FOXA1 MCF7GSE15244 64110855 64112954 2099 0
FOXA1 MCF7GSE15244 64113548 64114012 464 0
FOXA1 MCF7GSE15244 64117591 64119855 2264 0
FOXA1 MCF7GSE15244 64122027 64122695 668 0
FOXA1 MCF7GSE15244 64123154 64123973 819 0
FOXA1 MCF7GSE15244 64147187 64148847 1660 0
FOXA1 MCF7GSE15244 64149383 64150727 1344 0
FOXA1 MCF7GSE15244 64168330 64169172 842 0
FOXA1 MCF7GSE15244 64170357 64171241 884 0
FOXA1 MCF7GSE15244 64174398 64175264 866 0
FOXA1 MCF7GSE15244 64180791 64182368 1577 0
FoxA1 MCF7MACSdata 64111234 64112113 879 0
Nanog ESGSE20650 64157227 64157687 460 0
Nanog ESGSE20650 64179456 64180034 578 0
Nanog hESGSE18292 64070409 64070718 309 0
Nanog hESGSE18292 64157123 64157638 515 0
Nanog hESGSE18292 64179381 64179963 582 0
Oct1 HelaGSE14283 64056279 64056336 57 0
Oct1 HelaGSE14283 64061384 64061411 27 0
Oct4 hESGSE21916 64055255 64055897 642 0
Oct4 hESGSE21916 64179452 64180011 559 0
P300 T30-glioblastomaGSE21026 64111344 64112175 831 0
RARA MCF7GSE15244 64055018 64055530 512 0
RARA MCF7GSE15244 64055950 64056935 985 0
RARA MCF7GSE15244 64060914 64061604 690 0
RARA MCF7GSE15244 64065001 64066457 1456 0
RARA MCF7GSE15244 64070534 64071258 724 0
RARA MCF7GSE15244 64082522 64083966 1444 0
RARA MCF7GSE15244 64091630 64092742 1112 0
RARA MCF7GSE15244 64095644 64097553 1909 0
RARA MCF7GSE15244 64101609 64102860 1251 0
RARA MCF7GSE15244 64110226 64114182 3956 0
RARA MCF7GSE15244 64116760 64119880 3120 0
RARA MCF7GSE15244 64122027 64124084 2057 0
RARA MCF7GSE15244 64125359 64126190 831 0
RARA MCF7GSE15244 64145501 64146460 959 0
RARA MCF7GSE15244 64147152 64148847 1695 0
RARA MCF7GSE15244 64149383 64150693 1310 0
RARA MCF7GSE15244 64151464 64152036 572 0
RARA MCF7GSE15244 64163922 64164307 385 0
RARA MCF7GSE15244 64168368 64169387 1019 0
RARA MCF7GSE15244 64170357 64171529 1172 0
RARA MCF7GSE15244 64179928 64181656 1728 0
RARA MCF7GSE15244 64184810 64186443 1633 0
RARG MCF7GSE15244 64065037 64066703 1666 0
RARG MCF7GSE15244 64068931 64069250 319 0
RARG MCF7GSE15244 64082522 64083768 1246 0
RARG MCF7GSE15244 64110226 64113209 2983 0
RARG MCF7GSE15244 64113514 64114080 566 0
RARG MCF7GSE15244 64117539 64119880 2341 0
RARG MCF7GSE15244 64147152 64148847 1695 0
RARG MCF7GSE15244 64149383 64150727 1344 0
RARG MCF7GSE15244 64168368 64169331 963 0
RARG MCF7GSE15244 64170357 64171529 1172 0
RARG MCF7GSE15244 64174183 64175264 1081 0
RARG MCF7GSE15244 64180791 64182627 1836 0
Sox2 hESGSE18292 64070372 64070782 410 0
TFAP2C MCF7GSE21234 64108947 64110519 1572 0
p130 shRbQuiescentGSE19898 64111185 64111893 708 0
p130 shRbQuiescentGSE19898 64147585 64148037 452 0
p130 shRbSenescentGSE19898 64111226 64111966 740 0
p63 keratinocytesGSE17611 64111909 64112842 933 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
18244 mRNA chr3 64028679 64063845 3101 mRNA PRICKLE2 chr3 64054590 64186171Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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