AutismKB 2.0

Annotation Detail for DHX15


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Basic Information Top
Gene Symbol:DHX15 ( DBP1,DDX15,HRH2,PRP43,PRPF43,PrPp43p )
Gene Full Name: DEAH (Asp-Glu-Ala-His) box polypeptide 15
Band: 4p15.2
Quick LinksEntrez ID:1665; OMIM: 603403; Uniprot ID:DHX15_HUMAN; ENSEMBL ID: ENSG00000109606; HGNC ID: 2738
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
15Phosphoserine.
132N6-acetyllysine.
263DEAH box.
476Phosphothreonine.
488N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
82Phosphoserine(IKK)HMM predict
85Phosphoserine(CK1)HMM predict
91Phosphoserine(CK1)HMM predict
94Phosphoserine(CK1)HMM predict
100Phosphoserine(CK1)HMM predict
147Phosphothreonine(PKA)HMM predict
228Phosphoserine(CK1)HMM predict
266Phosphothreonine(PKA)HMM predict
284PhosphoserineHMM predict
331Phosphotyrosine(Syk)HMM predict
499Phosphotyrosine(EGFR)HMM predict
582N-linkedHMM predict
585N-linkedHMM predict
604Phosphothreonine(PKC)HMM predict
678Phosphothreonine(PKA)HMM predict
686Phosphotyrosine(INSR)HMM predict
783IsoleucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001358
  • Location:chr4 24138187-24195281
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FoxA1 MCF7MACSdata 24206445 24206720 275 11301
Myc hESGSE17917 24195083 24195535 452 28
Rb GrowingGSE19898 24195200 24195552 352 95
Rb QuiescentGSE19898 24195193 24195537 344 84
Rb SenescentGSE19898 24195044 24195640 596 61
Rb shRbSenescenceGSE19898 24195244 24195483 239 82
TFAP2C MCF7GSE21234 24205502 24205994 492 10467
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 24136070 24136106 36 2100
Oct1 HelaGSE14283 24132417 24132453 36 5753
Oct1 HelaGSE14283 24136070 24136106 36 2100
p63 keratinocytesGSE17611 24132007 24133007 1000 5681
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 24162300 24162533 233 0
CTCF CD4SISSRdata 24162300 24162533 233 0
CTCF G2GSE9613 24161777 24162098 321 0
CTCF G2GSE9613 24194365 24195465 1100 0
ETS1 JurkatGSE17954 24194717 24195825 1108 0
H3K4me3 colorectalcancer 24192843 24194510 1667 0
H3ac HepG2E 24192735 24193614 879 0
H3ac HepG2E 24193913 24194711 798 0
Oct1 H2O2-HelaGSE14283 24188756 24188788 32 0
Oct1 HelaGSE14283 24188751 24188790 39 0
P300 T30-glioblastomaGSE21026 24194023 24195674 1651 0
PHF8 293TGSE20725 24194781 24195690 909 0
PHF8 HeLaGSE20725 24194244 24195688 1444 0
PHF8 Hs68plusFBSGSE20725 24193859 24195899 2040 0
Rb QuiescentGSE19898 24194075 24194488 413 0
Rb SenescentGSE19898 24194031 24194858 827 0
hScc1 BcellGSE12603 24194301 24195465 1164 0
p130 QuiescentGSE19898 24194055 24194611 556 0
p130 QuiescentGSE19898 24194987 24195569 582 0
p130 SenescentGSE19898 24194093 24195019 926 0
p130 SenescentGSE19898 24195026 24195473 447 0
p130 shRbQuiescentGSE19898 24194031 24195740 1709 0
p130 shRbSenescentGSE19898 24194146 24194544 398 0
p130 shRbSenescentGSE19898 24194646 24195681 1035 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 15685193
hsa-miR-1 hsa-mir-1-1 20 15685193
hsa-miR-1 hsa-mir-1-2 18 15685193
hsa-miR-1 hsa-mir-1-1 20 15685193
hsa-miR-124 hsa-mir-124-1 8 15685193
hsa-miR-124 hsa-mir-124-2 8 15685193
hsa-miR-124 hsa-mir-124-3 20 15685193
hsa-miR-124 hsa-mir-124-1 8 15685193
hsa-miR-124 hsa-mir-124-2 8 15685193
hsa-miR-124 hsa-mir-124-3 20 15685193
hsa-miR-373 hsa-mir-373 19 15685193
hsa-miR-373 hsa-mir-373 19 15685193
hsa-miR-373* hsa-mir-373 19 15685193
hsa-miR-373* hsa-mir-373 19 15685193
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
205 Unknown MicroArray miR-1 DHX15 n_a 15685193
1151 Unknown pSILAC miR-1 DHX15 down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000109606 "cardiac and skeletal muscles, cardiogenesis" n_a n_a "epithelium, lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
ENSG00000109606 n_a n_a n_a "epithelium, lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018