Annotation Detail for DECR1

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Basic Information Top

Gene Symbol:	DECR1 ( DECR,NADPH,SDR18C1 )
Gene Full Name:	2,4-dienoyl CoA reductase 1, mitochondrial
Band:	8q21.3
Quick Links	Entrez ID:1666; OMIM: 222745; Uniprot ID:DECR_HUMAN; ENSEMBL ID: ENSG00000104325; HGNC ID: 2753
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:2 results
Experimental PTM Sites from dbPTM:1 results
Predicted PTM Sites by profile HMM from dbPTM:4 results

Location(AA)	Modification
110	N6-acetyllysine (By similarity).
230	N6-acetyllysine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_001359
Location:chr8 91082755-91133402
strand:+

Upstream the gene:13 results
Downstream the gene:2 results
Inside the gene:17 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	91076991	91077254	263	5633
CTCF	CD4	GSE12889	91082190	91082904	714	209
CTCF	CD4	SISSRdata	91076991	91077254	263	5633
CTCF	CD4	SISSRdata	91082190	91082904	714	209
FOXA1	MCF7	GSE15244	91082105	91082715	610	346
RARA	MCF7	GSE15244	91082105	91082609	504	399
RARG	MCF7	GSE15244	91082180	91082571	391	380
hScc1	Bcell	GSE12603	91077095	91077396	301	5510
hScc1	Bcell	GSE12603	91082105	91083041	936	183
hScc1	CdLS	GSE12603	91077095	91077396	301	5510
hScc1	CdLS	GSE12603	91082105	91083254	1149	76
p130	Quiescent	GSE19898	91082537	91082903	366	36
p130	Senescent	GSE19898	91082633	91082863	230	8

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	MCF7	GSE19013	91134221	91134700	479	1058
Oct1	H2O2-Hela	GSE14283	91134764	91134791	27	1375

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	91082142	91083638	1496	0
ER	Fulvestrant-MCF7	GSE14664	91087908	91087946	38	0
ER	Fulvestrant-MCF7	GSE14664	91092932	91092973	41	0
ER	MCF7	GSE19013	91082725	91083596	871	0
FOXA1	MCF7	GSE15244	91082995	91083443	448	0
H3K4me3	colorectal	cancer	91083072	91084195	1123	0
H3ac	HepG2	E	91083041	91084480	1439	0
Oct1	H2O2-Hela	GSE14283	91086586	91086621	35	0
Oct1	H2O2-Hela	GSE14283	91100335	91100378	43	0
Oct1	Hela	GSE14283	91086585	91086631	46	0
Oct1	Hela	GSE14283	91101775	91101803	28	0
Oct1	Hela	GSE14283	91102153	91102186	33	0
PHF8	Hs68plusFBS	GSE20725	91082101	91083416	1315	0
TAF	k562	GSE8489	91083291	91083929	638	0
hScc1	G2	GSE9613	91082180	91083443	1263	0
p130	Quiescent	GSE19898	91083767	91083925	158	0
p130	shRbQuiescent	GSE19898	91082299	91083495	1196	0

Validated miRNA targets

miR Walk:12 results
Tarbase V5.0:0 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-155	hsa-mir-155	21	19783678
hsa-miR-155*	hsa-mir-155	21	19783678
hsa-miR-195	hsa-mir-195	17	20952681
hsa-miR-195*	hsa-mir-195	17	20952681
hsa-miR-199a-3p	hsa-mir-199a-1	19	19783678
hsa-miR-199a-3p	hsa-mir-199a-2	1	19783678
hsa-miR-199a-5p	hsa-mir-199a-1	19	19783678
hsa-miR-199a-5p	hsa-mir-199a-2	1	19783678
hsa-miR-199b-3p	hsa-mir-199b	9	19783678
hsa-miR-199b-5p	hsa-mir-199b	9	19783678
hsa-miR-25	hsa-mir-25	7	21071935
hsa-miR-25*	hsa-mir-25	7	21071935

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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