Annotation Detail for DHFR
Basic Information Top
| Gene Symbol: | DHFR ( DHFRP1,DYR ) |
|---|---|
| Gene Full Name: | dihydrofolate reductase |
| Band: | 5q14.1 |
| Quick Links | Entrez ID:1719; OMIM: 126060; Uniprot ID:DYR_HUMAN; ENSEMBL ID: ENSG00000228716; HGNC ID: 2861 |
| Relate to Another Database: | SFARIGene; denovo-db |
| No data |
| No data |
| Location(AA) | Modification | Resource |
|---|---|---|
| 39 | Phosphothreonine(PKA) | HMM predict |
| 122 | Phosphotyrosine(Syk) | HMM predict |
| 183 | Phosphotyrosine(INSR) | HMM predict |
- RefSeq ID: NM_000791
- Location:chr5 79957800-79986555
- strand:-
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| PAX3-FKHR | Rh4 | GSE19063 | 79955001 | 79956319 | 1318 | 2141 |
| hScc1 | Bcell | GSE12603 | 79946702 | 79947062 | 360 | 10919 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| AR | prostate-cancer | GSE14092 | 79982057 | 79983700 | 1643 | 0 |
| CTCF | G2 | GSE9613 | 79985830 | 79986694 | 864 | 0 |
| E2F4 | G0 | GSE7516 | 79985513 | 79986214 | 701 | 0 |
| ERG | prostate-cancer | GSE14092 | 79982202 | 79984066 | 1864 | 0 |
| H3K4me3 | colorectal | cancer | 79984793 | 79985804 | 1011 | 0 |
| H3ac | HepG2 | E | 79984549 | 79985768 | 1219 | 0 |
| LIN9 | G0 | GSE7516 | 79984757 | 79986250 | 1493 | 0 |
| LIN9 | S | GSE7516 | 79984975 | 79986250 | 1275 | 0 |
| Myc | hES | GSE17917 | 79982461 | 79983154 | 693 | 0 |
| Myc | hES | GSE17917 | 79983337 | 79984040 | 703 | 0 |
| PHF8 | 293T | GSE20725 | 79985551 | 79986930 | 1379 | 0 |
| PHF8 | HeLa | GSE20725 | 79985442 | 79987173 | 1731 | 0 |
| Pol2 | GM12878 | GSE19551 | 79986070 | 79986988 | 918 | 0 |
| RARA | MCF7 | GSE15244 | 79982086 | 79983774 | 1688 | 0 |
| TAF | Hela | GSE8489 | 79984757 | 79986074 | 1317 | 0 |
| hScc1 | Bcell | GSE12603 | 79985830 | 79986657 | 827 | 0 |
| hScc1 | CdLS | GSE12603 | 79985830 | 79986694 | 864 | 0 |
| p130 | Quiescent | GSE19898 | 79985495 | 79986224 | 729 | 0 |
| p130 | Senescent | GSE19898 | 79985620 | 79986505 | 885 | 0 |
| p130 | shRbQuiescent | GSE19898 | 79985790 | 79986464 | 674 | 0 |
| p130 | shRbSenescent | GSE19898 | 79985655 | 79986363 | 708 | 0 |
| p130 | G0 | GSE7516 | 79985200 | 79986250 | 1050 | 0 |
| p130 | S | GSE7516 | 79984549 | 79986250 | 1701 | 0 |
Validated miRNA targets| Cluster ID | Plue Type | Plus Gene Name | Plus Chromosome | Plus Start | Plus End | Overlap Length | Minus Type | Minus Gene Name | Minus Chromosome | Minus Star | Minus End | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 21174 | mRNA | MSH3 | chr5 | 79986294 | 80208389 | 217 | mRNA | DHFR | chr5 | 79957803 | 79986572 | Sense/Antisense (SA) pairs |