AutismKB 2.0

Annotation Detail for DLG1


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Basic Information Top
Gene Symbol:DLG1 ( DKFZp761P0818,DKFZp781B0426,DLGH1,SAP-97,SAP97,dJ1061C18.1.1,hdlg )
Gene Full Name: discs, large homolog 1 (Drosophila)
Band: 3q29
Quick LinksEntrez ID:1739; OMIM: 601014; Uniprot ID:DLG1_HUMAN; ENSEMBL ID: ENSG00000075711; HGNC ID: 2900
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
115Phosphothreonine.
122Phosphoserine.
232Phosphoserine (By similarity).
301Phosphoserine (By similarity).
399Phosphotyrosine (By similarity).
575Phosphoserine.
619Phosphoserine.
683Phosphothreonine (By similarity).
684Phosphoserine.
687Phosphoserine.
760Phosphotyrosine.
Location(AA) Modifications Resource
232Phosphoserine (By similarity).Swiss-Prot 53.0
232Phosphoserine (CaM-KII
301Phosphoserine (By similarity).Swiss-Prot 53.0
683Phosphothreonine (By similarity).Swiss-Prot 53.0
684Phosphoserine.Swiss-Prot 53.0
684PhosphoserinePhospho.ELM 6.0
687Phosphoserine.Swiss-Prot 53.0
687PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
8Phosphothreonine(PKC)HMM predict
8Phosphothreonine(PKA)HMM predict
20Phosphoserine(CK1)HMM predict
23Phosphoserine(ATM)HMM predict
23Phosphoserine(CK2)HMM predict
23Phosphoserine(PKG)HMM predict
33Phosphoserine(CK1)HMM predict
90Phosphoserine(IKK)HMM predict
91O-linkedHMM predict
93O-linkedHMM predict
96O-linkedHMM predict
99O-linkedHMM predict
102Phosphoserine(CDC2)HMM predict
102Phosphoserine(MAPK)HMM predict
115Phosphothreonine(MAPK)HMM predict
122Phosphoserine(ATM)HMM predict
141N-linkedHMM predict
143Phosphoserine(CK2)HMM predict
143Phosphoserine(CK1)HMM predict
147N-linkedHMM predict
169O-linkedHMM predict
214N-linkedHMM predict
220SulfotyrosineHMM predict
222Phosphotyrosine(Syk)HMM predict
222SulfotyrosineHMM predict
324O-linkedHMM predict
349Phosphotyrosine(EGFR)HMM predict
393N-linkedHMM predict
414Phosphotyrosine(Syk)HMM predict
414Phosphotyrosine(INSR)HMM predict
420O-linkedHMM predict
421N-linkedHMM predict
424Phosphoserine(ATM)HMM predict
443Phosphoserine(MAPK)HMM predict
443Phosphoserine(CDC2)HMM predict
451O-linkedHMM predict
550Phosphotyrosine(EGFR)HMM predict
550Phosphotyrosine(SRC)HMM predict
566N-linkedHMM predict
571Phosphoserine(CK1)HMM predict
602Phosphoserine(ATM)HMM predict
617N-linkedHMM predict
630Phosphothreonine(PKA)HMM predict
657Phosphothreonine(PKC)HMM predict
685N-linkedHMM predict
687Phosphoserine(CAMK2)HMM predict
691Phosphoserine(CK1)HMM predict
712N-linkedHMM predict
713Phosphotyrosine(Abl)HMM predict
753Phosphotyrosine(Syk)HMM predict
881Phosphotyrosine(Syk)HMM predict
881Phosphotyrosine(Jak)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004087
  • Location:chr3 198255819-198509843
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 198509598 198510253 655 82
H3ac HepG2E 198510449 198511649 1200 1206
Jun K562GSE19551 198528519 198528808 289 18820
PHF8 293TGSE20725 198509116 198510671 1555 50
RARA MCF7GSE15244 198510675 198511104 429 1046
RARA MCF7GSE15244 198520814 198521599 785 11363
RARG MCF7GSE15244 198520989 198521599 610 11451
TFAP2C MCF7GSE21234 198528543 198529007 464 18932
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 198398232 198398570 338 0
CTCF CD4GSE12889 198468206 198468397 191 0
CTCF CD4SISSRdata 198398232 198398570 338 0
CTCF CD4SISSRdata 198468206 198468397 191 0
CTCF G2GSE9613 198336959 198337326 367 0
CTCF G2GSE9613 198398171 198398586 415 0
CTCF G2GSE9613 198435261 198435482 221 0
CTCF G2GSE9613 198468117 198469151 1034 0
CTCF G2GSE9613 198508756 198509826 1070 0
Fos K562GSE19551 198509162 198510277 1115 0
H3K4me2 HCT116GSE10453 198508190 198508653 463 0
H3K4me3 colorectalcancer 198507833 198508828 995 0
H3ac HepG2E 198508155 198508861 706 0
NFkBII GM12878GSE19485 198261267 198263417 2150 0
NFkBII GM12892GSE19485 198261550 198263350 1800 0
Nanog hESGSE18292 198415024 198415477 453 0
P300 T30-glioblastomaGSE21026 198314988 198315418 430 0
PHF8 HeLaGSE20725 198508755 198510836 2081 0
RARA MCF7GSE15244 198508155 198508566 411 0
hScc1 BcellGSE12603 198398298 198398586 288 0
hScc1 BcellGSE12603 198508529 198509852 1323 0
hScc1 CdLSGSE12603 198398137 198398586 449 0
hScc1 CdLSGSE12603 198435201 198435595 394 0
hScc1 CdLSGSE12603 198468151 198468694 543 0
hScc1 G2GSE9613 198398171 198398586 415 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
19252 mRNA chr3 198513432 198518924 159 mRNA DLG1 chr3 198259732 198513757Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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