AutismKB 2.0

Annotation Detail for DLX2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DLX2 ( TES-1,TES1 )
Gene Full Name: distal-less homeobox 2
Band: 2q31.1
Quick LinksEntrez ID:1746; OMIM: 126255; Uniprot ID:DLX2_HUMAN; ENSEMBL ID: ENSG00000115844; HGNC ID: 2915
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
227Phosphoserine.
232Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
31O-linkedHMM predict
40N-linkedHMM predict
42O-linkedHMM predict
43O-linkedHMM predict
44O-linkedHMM predict
44Phosphoserine(CK1)HMM predict
46Phosphoserine(CK1)HMM predict
60O-linkedHMM predict
64O-linkedHMM predict
66PhosphotyrosineHMM predict
67SulfotyrosineHMM predict
67Phosphotyrosine(Syk)HMM predict
84Phosphotyrosine(INSR)HMM predict
112Phosphotyrosine(INSR)HMM predict
117O-linkedHMM predict
124Phosphothreonine(PKC)HMM predict
124O-linkedHMM predict
127Phosphoserine(IKK)HMM predict
127Phosphoserine(CDC2)HMM predict
161Phosphoserine(CDK)HMM predict
225O-linkedHMM predict
227O-linkedHMM predict
232O-linkedHMM predict
232Phosphoserine(CDC2)HMM predict
257O-linkedHMM predict
260O-linkedHMM predict
265Phosphoserine(ATM)HMM predict
267Phosphoserine(IKK)HMM predict
267O-linkedHMM predict
267O-linkedHMM predict
268Phosphoserine(CDC2)HMM predict
303O-linkedHMM predict
303O-linkedHMM predict
305Phosphothreonine(CDC2)HMM predict
305Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004405
  • Location:chr2 172672412-172675723
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF HelaGSE12889 172676916 172677219 303 1344
CTCF G2GSE9613 172676830 172677470 640 1427
CTCF G2GSE9613 172681035 172681265 230 5427
CTCF G2GSE9613 172683020 172683301 281 7437
CTCF G2GSE9613 172686562 172686905 343 11010
Fos K562GSE19551 172675636 172676309 673 249
H3K27me3 colorectalcancer 172678211 172678949 738 2857
H3K27me3 colorectalcancer 172679482 172679835 353 3935
Rb shRbSenescenceGSE19898 172676187 172676441 254 591
USF1 HepG2E 172674776 172676968 2192 149
USF2 HepG2E 172674776 172676769 1993 49
hScc1 BcellGSE12603 172676769 172677222 453 1272
hScc1 BcellGSE12603 172679130 172679760 630 3722
hScc1 CdLSGSE12603 172675889 172677491 1602 967
hScc1 CdLSGSE12603 172686529 172686941 412 11012
hScc1 G2GSE9613 172676769 172677470 701 1396
hScc1 G2GSE9613 172681035 172681265 230 5427
hScc1 G2GSE9613 172686459 172686941 482 10977
p130 SenescentGSE19898 172675445 172676058 613 28
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 172667397 172667807 410 4811
CTCF G2GSE9613 172668274 172668822 548 3865
PHF8 HeLaGSE20725 172667449 172668824 1375 4276
TAF k562GSE8489 172670887 172671613 726 1163
TFAP2C MCF7GSE21234 172668247 172668925 678 3827
TFAP2C MCF7GSE21234 172670232 172670531 299 2031
TFAP2C MCF7GSE21234 172671545 172672269 724 506
hScc1 BcellGSE12603 172671962 172672347 385 258
hScc1 G2GSE9613 172667397 172668955 1558 4237
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 172673032 172673977 945 0
CTCF G2GSE9613 172674573 172676271 1698 0
H3K27me3 colorectalcancer 172674643 172675441 798 0
HIF1 HypoHepG2 172675171 172676128 957 0
HIF1 NormHepG2 172674538 172676534 1996 0
Rb GrowingGSE19898 172675034 172675220 186 0
hScc1 BcellGSE12603 172673416 172673689 273 0
hScc1 BcellGSE12603 172674303 172674643 340 0
hScc1 G2GSE9613 172674744 172676489 1745 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-452 hsa-mir-452 X 21098571
hsa-miR-452* hsa-mir-452 X 21098571
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved